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Monoamine oxidase A Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
ClorgilineIC504.46 [1]
ClorgilineKi0.3 [1], 12.0 [2]
IproniazidIC506560.0 [1]
SelegilineIC5067250.0 [1]
SelegilineKi3600.0 [1], 9060.0 [2], 16890.0 [3], 67250.0 [4]
MoclobemideIC50361380.0 [1]
MoclobemideKi5.0 [1], 14.0 [2], 102.0 [3], 110.0 [4]
RasagilineIC501420.0 [1]
RasagilineKi9700.0 [1]
ToloxatoneIC503920.0 [1]
ToloxatoneKi1500.0 [1]
PargylineIC503520.0 [1]
(1S,2R)-2-Phenylcyclopropan-1-amine;(1R,2S)-2-phenylcyclopropan-1-amineIC502100.0 [1]
ParnateIC506000.0 [1]
ParnateKi102000.0 [1]
IsatinIC5040000.0 [1], 56234.13 [2]
IsatinKi15000.0 [1]
SafinamideIC5050000.0 [1]
SafinamideKi365000.0 [1]
4-(1-Benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-2-yl)methyl-prop-2-ynylamino]butanenitrileIC503800.0 [1]
IadademstatIC5048380.0 [1]
LinezolidIC5046000.0 [1]
LinezolidKi7900.0 [1], 20000.0 [2], 53000.0 [3], 55000.0 [4]
ApigeninIC50640.0 [1], 1550.0 [2], 1700.0 [3]
AcacetinIC50121.0 [1], 190.0 [2]
AcacetinKi59.2 [1]
Benzyl N-[1-[4-(2-aminocyclopropyl)anilino]-1-oxo-3-phenylpropan-2-yl]carbamateIC50320.0 [1], 1200.0 [2]
Benzyl N-[1-[4-(2-aminocyclopropyl)anilino]-1-oxo-3-phenylpropan-2-yl]carbamateKi1200.0 [1], 4000.0 [2]
1-[3-(2,4-Dichloro-phenoxy)-propyl]-1,2,3,6-tetrahydro-pyridineIC502600.0 [1]
1-[3-(2,4-Dichloro-phenoxy)-propyl]-1,2,3,6-tetrahydro-pyridineKi900.0 [1], 2200.0 [2], 7400.0 [3]
HarmineKi5.0 [1], 16.9 [2], 17.0 [3]
PurpurinIC502500.0 [1]
PurpurinKi422.0 [1]
LadostigilIC5085000.0 [1], 100000.0 [2]
LadostigilKi227000.0 [1]
Tranylcypromine hydrochlorideIC504500.0 [1], 10600.0 [2], 20000.0 [3]
1-PhenethylpiperidineIC50757300.0 [1]
1-PhenethylpiperidineKi121400.0 [1], 3681000.0 [2]
AplysinopsinIC5035.0 [1], 10017.0 [2]
4-Imidazolidinone, 5-((6-bromo-1H-indol-3-yl)methylene)-2-imino-1,3-dimethyl-IC505.6 [1], 447.0 [2]
5-BenzyloxyphthalimideIC504170.0 [1]
5-BenzyloxyphthalimideKi1100.0 [1]
6-[(4-Chlorophenyl)methoxy]-1,3-benzoxathiol-2-oneIC50189.0 [1]
6-[(4-Chlorophenyl)methoxy]-1,3-benzoxathiol-2-oneKi360.0 [1], 560.0 [2]
6-(3-Phenylpropoxy)-3H-2-benzofuran-1-oneIC5096.0 [1]
6-(3-Phenylpropoxy)-3H-2-benzofuran-1-oneKi25.0 [1], 62.0 [2]
4-Methyl-1-(2-phenylethyl)-3,6-dihydro-2H-pyridineIC50623400.0 [1]
4-Methyl-1-(2-phenylethyl)-3,6-dihydro-2H-pyridineKi407900.0 [1], 2587000.0 [2]
7-[[4-(Trifluoromethyl)phenyl]methoxy]chromen-4-oneIC501970.0 [1], 18940.0 [2]
4-N-[(1S,2R)-2-[4-[3-(Trifluoromethyl)phenyl]phenyl]cyclopropyl]cyclohexane-1,4-diamineIC5010700.0 [1], 14640.0 [2], 50000.0 [3]
QuercetinIC502440.0 [1], 2800.0 [2]
1,4-BenzoquinoneIC504820.0 [1]
1,4-BenzoquinoneKi9620.0 [1]
DonepezilIC50850000.0 [1], 1000000.0 [2]
ChelerythrineIC50550.0 [1]
ChelerythrineKi220.0 [1]
DeprenylIC5067250.0 [1]
TranylcypromineIC504720.0 [1], 11500.0 [2]
PhenelzineIC50238.0 [1]
PhenelzineKi163.0 [1]
N-Propargyl-1(S)-aminoindanIC5017700.0 [1]
N-Propargyl-1(S)-aminoindanKi112000.0 [1]
DecursinIC501760.0 [1]
Alternariol monomethyl etherIC501710.0 [1]
TedizolidIC508700.0 [1]
TedizolidKi2000.0 [1]
MofegilineIC501780.0 [1]
MofegilineKi1100.0 [1]
2-(Phenylazo)pyridineIC5018000.0 [1]
2-(Phenylazo)pyridineKi5100.0 [1]
N-[(5-Phenylmethoxy-1H-indol-2-yl)methyl]prop-2-yn-1-amineIC50287.3 [1], 790.0 [2]
CID 53378764IC504.2 [1], 58.2 [2]
(E)-N'-(1-(5-Chloro-2-hydroxyphenyl)ethylidene)-3-(morpholinosulfonyl)benzohydrazideIC50300000.0 [1]
HispidolIC50260.0 [1]
HispidolKi100.0 [1]
1,4-Naphthalenedione, 2,3,6-trimethyl-Ki3000.0 [1], 6000.0 [2]
4-(2-Pyridylazo)-N,N-dimethylanilineIC507900.0 [1]
4-(2-Pyridylazo)-N,N-dimethylanilineKi2300.0 [1]
N-[(2S)-4-[3-(2-Aminocyclopropyl)phenoxy]-1-(benzylamino)-1-oxobutan-2-yl]benzamideIC50230000.0 [1]
N-[(2S)-4-[3-(2-Aminocyclopropyl)phenoxy]-1-(benzylamino)-1-oxobutan-2-yl]benzamideKi230000.0 [1]
N-Phenylpyridine-2-methylamineIC5020000.0 [1]
N-Phenylpyridine-2-methylamineKi5700.0 [1]
3,4-Dimethyl-7-(3,4-difluorobenzyloxy)coumarinIC50123.0 [1], 100000.0 [2]
N-[(2S)-4-[4-[(1S,2R)-2-Aminocyclopropyl]phenoxy]-1-(benzylamino)-1-oxobutan-2-yl]benzamideIC50290000.0 [1]
N-[(2S)-4-[4-[(1S,2R)-2-Aminocyclopropyl]phenoxy]-1-(benzylamino)-1-oxobutan-2-yl]benzamideKi250000.0 [1]
N-(4-Chlorophenyl)-4-oxochromene-3-carboxamideIC5010000.0 [1], 100000.0 [2]
N,N-Dimethyl-4-(pyridin-2-ylmethylideneamino)anilineIC50360.0 [1]
N,N-Dimethyl-4-(pyridin-2-ylmethylideneamino)anilineKi100.0 [1]
Pyridine, 2-(N-phenylformimidoyl)-IC50129000.0 [1]
Pyridine, 2-(N-phenylformimidoyl)-Ki37000.0 [1]
4-Hydroxybenzoic (2-hydroxybenzylidene)hydrazideIC5088500.0 [1]
N-(3,4-Dihydroxyphenyl)-4-oxochromene-2-carboxamideIC50190.0 [1], 190.55 [2]
N-[(E)-(2-Methylcyclohexylidene)amino]-4-phenyl-1,3-thiazol-2-amineIC5041230.0 [1], 41236.0 [2]
4-(4-Methoxyphenyl)-N-[(E)-(2-methylcyclohexylidene)amino]-1,3-thiazol-2-amineIC502760.0 [1], 2762.0 [2]
4-(4-Chlorophenyl)-N-[(E)-(2-methylcyclohexylidene)amino]-1,3-thiazol-2-amineIC5035220.0 [1]
7-Methoxy-3-(3-trifluoromethyl-phenyl)-indeno[1,2-c]pyridazin-5-oneIC5038.0 [1], 1000.0 [2]
8-Methoxy-3-[3-(trifluoromethyl)phenyl]indeno[1,2-c]pyridazin-5-oneIC500.1 [1], 1000.0 [2]
7-Acetonyloxy-3-acetylamino-8-methoxycoumarinIC505310.0 [1], 6430.0 [2]
N-[(2S)-1-[(3-Chlorophenyl)methylamino]-1-oxo-6-[[(1R,2S)-2-phenylcyclopropyl]amino]hexan-2-yl]-4-phenylbenzamideIC50100000.0 [1]
6-((4-Chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-oneIC50238.0 [1], 340.0 [2]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Monoamine oxidase A Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/monoamine-oxidase-a-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Monoamine oxidase A Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/monoamine-oxidase-a-inhibitors-ic50-ki.
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