logo
AAT Bioquest

 
search
logo
AAT Bioquest
Image Gallery
Contact us
Company
Telephone:1-408-733-1055
Fax:1-408-733-1304
Hours:Monday to Friday
8:30 - 17:30 PST (GMT-8)
Location:5775 W Las Positas Blvd.
Pleasanton, CA, 94588
USA

Email us
Sales:sales@aatbio.com
Technical Support:support@aatbio.com
Website:websupport@aatbio.com
General Inquiries:info@aatbio.com
Order info
United States of America
Telephone:1-408-733-1055
Fax:1-408-733-1304
Email:sales@aatbio.com
Purchase Order:sales@aatbio.com

International
Click here to see all available distributors
 
search
calculatorCalculator

MLL1-ASH2L/RbBP5/WDR5/DPY30 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
N-Benzhydryl-1-[[(2S)-5-(diaminomethylideneamino)-2-[[2-ethyl-2-(2-methylpropanoylamino)butanoyl]amino]pentanoyl]amino]cyclopentane-1-carboxamideIC50578.0 [1]
MM-589 (Tfa)IC5012.7 [1]
N-[(3R,6S,9S,12R)-9-[3-[(N,N'-Dimethylcarbamimidoyl)amino]propyl]-6-ethyl-12-methyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC501259.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-1,12-dimethyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC50190.0 [1]
N-[(3R,6S,9S,12R)-6-Ethyl-12-methyl-9-[3-[(N'-methylcarbamimidoyl)amino]propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclooctadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC50216.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-12-methyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclotetradec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC5012.6 [1]
N-[(3S,6S,9S,12R)-6-Ethyl-12-methyl-9-[3-[(N'-methylcarbamimidoyl)amino]propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclotetradec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC50477.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclopentadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC5010000.0 [1]
N-[(3R,6S,9S,12R)-6-Ethyl-12-methyl-9-[3-[(N'-methylcarbamimidoyl)amino]propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC50452.0 [1]
N-[(3R,6S,9S,12R)-6-Ethyl-12-methyl-9-[3-[(N'-methylcarbamimidoyl)amino]propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacycloicos-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC50744.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-12-methyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclopentadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC5084.8 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-3-(4-fluorophenyl)-1,12-dimethyl-2,5,8,11-tetraoxo-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC50138.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclotridec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC5010000.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC5010000.0 [1]
N-[(3R,6S,9S,12R)-3-(4-Chlorophenyl)-9-[3-(diaminomethylideneamino)propyl]-6-ethyl-1,12-dimethyl-2,5,8,11-tetraoxo-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC50124.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-12-methyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacycloheptadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC501527.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-12-methyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acidIC50373.0 [1]
N-[(3S,6R,9R,12S)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-12-methyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclohexadec-12-yl]-2-methylpropanamideIC5010000.0 [1]
N-[(3R,6S,9S,12R)-9-[3-(Diaminomethylideneamino)propyl]-6-ethyl-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclotetradec-12-yl]-2-methylpropanamideIC501800.0 [1]
Items per page: 1 - 10 of 19
⟨⟩

References

This online tool may be cited as follows

MLA

"Quest Database™ MLL1-ASH2L/RbBP5/WDR5/DPY30 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/mll1-ash2l-rbbp5-wdr5-dpy30-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ MLL1-ASH2L/RbBP5/WDR5/DPY30 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mll1-ash2l-rbbp5-wdr5-dpy30-inhibitors-ic50-ki.
BibTeXEndNoteRefMan