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Mixed lineage kinase 7 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
VemurafenibIC5023.0 [1], 31.4 [2]
4-(3-Pyridin-2-YL-1H-pyrazol-4-YL)quinolineIC501400.0 [1]
LY-2090314IC5020000.0 [1]
LY-3009120IC5039.0 [1]
3-Imidazo[1,2-a]pyridin-3-yl-4-[10-(morpholine-4-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]pyrrole-2,5-dioneIC5013400.0 [1]
3-(4-Imidazo[1,2-a]pyridin-3-yl-2,5-dioxopyrrol-3-yl)-N,N-dimethyl-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraene-10-carboxamideIC5020000.0 [1]
7-Chloro-3-oxo-8-(1,3-thiazol-5-ylmethylamino)-11,16-dioxa-2,4,19,21-tetrazatricyclo[15.3.1.05,10]henicosa-1(20),5,7,9,17(21),18-hexaene-18-carbonitrileKi8573.0 [1]
1-({4-[(3,4-Dichlorophenyl)methoxy]phenyl}methyl)azetidine-3-carboxylic acidIC5010000.0 [1]
3-[6-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzimidazol-1-yl]propan-1-olIC50708.0 [1]
4-[3-[6-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazol-1-yl]propyl]morpholineIC508480.0 [1]
3-Imidazo[1,2-a]pyridin-3-yl-4-[10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]pyrrole-2,5-dioneIC5020000.0 [1]
3-[6-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazol-1-yl]propan-1-olIC502810.0 [1]
Ripk1-IN-7IC50457.0 [1]
N,N-Diethyl-3-[6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazol-1-yl]propan-1-amineIC5020000.0 [1]
6-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1-(3-pyrrolidin-1-ylpropyl)benzimidazoleIC504880.0 [1]
5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamideIC5010000.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC5010000.0 [1]
6-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzimidazoleIC5020000.0 [1]
6-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-(3-pyrrolidin-1-ylpropyl)benzimidazoleIC5020000.0 [1]
5-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-[3-(oxan-2-yloxy)propyl]benzimidazoleIC5020000.0 [1]
1-Methyl-6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzimidazoleIC501310.0 [1]
1-[3-(Oxan-2-yloxy)propyl]-5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzimidazoleIC5020000.0 [1]
6-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-(3-piperidin-1-ylpropyl)benzimidazoleIC5020000.0 [1]
1-Methyl-6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazoleIC502340.0 [1]
Propan-2-yl 3-(4-imidazo[1,2-a]pyridin-3-yl-2,5-dioxopyrrol-3-yl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraene-10-carboxylateIC5020000.0 [1]
5-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-indoleIC5020000.0 [1]
6-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1H-benzimidazoleIC5015940.0 [1]
3-Bromo-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC505.0 [1]
3-Chloro-N-[2,4-difluoro-3-[2-(1-methylpyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC5030000.0 [1]
4-Chloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC5016.8 [1]
3-Chloro-N-[2,4-difluoro-3-[2-(1H-pyrrolo[2,3-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC5022.6 [1]
3-Chloro-N-[2,4-difluoro-3-[2-(3-propan-2-yloxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC5042.7 [1]
2,3-Dichloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC509.6 [1]
3-Chloro-N-[2,4-difluoro-3-[2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC505.1 [1]
3-Chloro-N-[2,4-difluoro-3-[2-(1H-indazol-5-yl)ethynyl]phenyl]benzenesulfonamideIC50994.1 [1]
N-[2,4-Difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC5019.2 [1]
N-[2,4-Difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-methoxybenzenesulfonamideIC507.5 [1]
3-Chloro-N-[3-[2-(3-cyclopentyloxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2,4-difluorophenyl]benzenesulfonamideIC50143.7 [1]
3-Chloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC504.2 [1]
2-Chloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC505.1 [1]
N-[2,4-Difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-methylbenzenesulfonamideIC5012.1 [1]
3-Cyano-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamideIC503.3 [1]
N,N-Dimethyl-3-[6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazol-1-yl]propan-1-amineIC5020000.0 [1]
N,N-Dimethyl-3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzimidazol-1-yl]propan-1-amineIC5015880.0 [1]
Indolocarbazole deriv. 14mIC509970.0 [1]
1-Methyl-5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)indoleIC5016610.0 [1]
1-Methyl-5-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]indoleIC5020000.0 [1]
1-Methyl-5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzimidazoleIC5020000.0 [1]
Items per page: 1 - 10 of 48
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References

This online tool may be cited as follows

MLA

"Quest Database™ Mixed lineage kinase 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/mixed-lineage-kinase-7-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Mixed lineage kinase 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mixed-lineage-kinase-7-inhibitors-ic50-ki.
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