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Mitogen-activated protein kinase 7 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
StaurosporineIC50121.6 [1], 6368.0 [2]
3-[[3-[(Dimethylamino)methyl]anilino]-phenylmethylidene]-N,N-dimethyl-2-oxo-1H-indole-6-carboxamideIC5059.0 [1]
Xmd8-92IC50240.0 [1]
MEK inhibitorIC50810.0 [1]
Erk5-IN-1IC50190.0 [1]
4-[(5,11-Dimethyl-6-oxopyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]benzenesulfonamideIC50310.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC5010000.0 [1]
(4S,6Z,9S,10R,12E)-9,10,18-Trihydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dioneIC50100000.0 [1]
2-[4-(4-Hydroxypiperidin-1-yl)-2-methoxyanilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50240.0 [1]
11-Ethyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50200.0 [1]
2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-11-propan-2-ylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50230.0 [1]
11-Cyclopentyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50200.0 [1]
9-Fluoro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC501320.0 [1]
8-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC501240.0 [1]
2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5,8,11-trimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC503100.0 [1]
2-[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50200.0 [1]
9-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC5011380.0 [1]
2-[2-Methoxy-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50130.0 [1]
4-[(5,11-Dimethyl-6-oxopyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamideIC50320.0 [1]
2-(2-Methoxy-4-morpholin-4-ylanilino)-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50260.0 [1]
5,11-Dimethyl-2-[2-methyl-4-(4-methylpiperazin-1-yl)anilino]pyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50280.0 [1]
2-[2-Methoxy-4-(1-methylpiperidin-4-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50260.0 [1]
2-(2-Methoxy-4-piperazin-1-ylanilino)-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-oneIC50230.0 [1]
N-[2-(Dimethylamino)ethyl]-4-[(5,11-dimethyl-6-oxopyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]-3-methoxybenzamideIC50240.0 [1]
5-(2,3-Difluorophenyl)-N-[[1-(2-methoxyethyl)piperidin-4-yl]methyl]-1H-indazole-3-carboxamideIC50220.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Mitogen-activated protein kinase 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Dec2024https://www.aatbio.com/data-sets/mitogen-activated-protein-kinase-7-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 20). Quest Database™ Mitogen-activated protein kinase 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mitogen-activated-protein-kinase-7-inhibitors-ic50-ki.
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