Metabotropic glutamate receptor 8 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 6324634	IC50	300000.0 [1]
	CID 6324634	Ki	300000.0 [1]
	Glutamic acid	IC50	5.7 [1]
	Glutamic acid	Ki	9500.0 [1]
	2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-Alanine	IC50	170.0 [1]
	2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-Alanine	Ki	170.0 [1]
	2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acid	IC50	300000.0 [1]
	2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acid	Ki	300000.0 [1]
	2-Methyl-6-(phenylethynyl)pyridine	Ki	100000.0 [1]
	(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acid	Ki	45000.0 [1]
	2-Amino-4-phosphonobutyric acid	IC50	5.1 [1]
	(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid	Ki	1700.0 [1]
	Eglumetad	Ki	12000.0 [1]
	(S)-4-((1-Carboxyethyl)amino)benzoic acid	IC50	1000000.0 [1]
	(2S)-2-Amino-4-phosphonobutanoic acid	Ki	61.0 [1]
	(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine	Ki	3400.0 [1]
	(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid	Ki	100000.0 [1]
	CPCCOEt	Ki	100000.0 [1]
	2-Methyl-6-(2-phenylethenyl)pyridine	Ki	100000.0 [1]
	6-Methyl-2-(phenylazo)-3-pyridinol	Ki	100000.0 [1]
	Benzonitrile, 3-fluoro-5-(2-(2-(fluoromethyl)-4-thiazolyl)ethynyl)-	Ki	10000.0 [1]
	(S)-3,5-Dihydroxyphenylglycine	Ki	1000000.0 [1]
	(RS)-Ppg	Ki	210.0 [1]
	4-Fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)thiazol-2-yl)-N-methylbenzamide	IC50	10000.0 [1]
	CID 10058694	Ki	7300.0 [1]
	Dfmti	IC50	10000.0 [1]
	(1r,2s,4r,5r,6r)-2-Amino-4-(1h-1,2,4-Triazol-3-Ylsulfanyl)bicyclo[3.1.0]hexane-2,6-Dicarboxylic Acid	IC50	12500.0 [1]
	1-Adamantyl-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanone	IC50	30000.0 [1]
	N-Methyl-5-(phenylethynyl)pyrimidin-2-amine	IC50	10000.0 [1]
	3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonitrile	Ki	10000.0 [1]
	1-Benzyl-APDC	IC50	300000.0 [1]
	(2R,4R)-4-Amino-1-naphthalen-1-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-phenylethyl)cyclopropane-1-carboxylic acid	IC50	990.0 [1]
	N-[4-Chloro-3-[dideuterio(fluoro)methoxy]phenyl]pyridine-2-carboxamide	IC50	30000.0 [1]
	2-(m-Tolylethynyl)pyrimidine	IC50	10000.0 [1]
	(2R,4R)-4-Amino-1-(3-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(2R,4R)-4-Amino-1-naphthalen-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(2R,4R)-4-Amino-1-[(2,6-dichlorophenyl)methyl]pyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(2R,4R)-4-Amino-1-methylpyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(2R,4R)-4-Amino-1-ethylpyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine-2,4-dicarboxylic acid	IC50	300000.0 [1]
	(2R,3R,6S)-2-Amino-3-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid	Ki	15000.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-butylcyclopropane-1-carboxylic acid	IC50	490.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-methylcyclopropane-1-carboxylic acid	IC50	1230.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-propylcyclopropane-1-carboxylic acid	IC50	2250.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-nonylcyclopropane-1-carboxylic acid	IC50	5180.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-hexylcyclopropane-1-carboxylic acid	IC50	750.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-pentylcyclopropane-1-carboxylic acid	IC50	340.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-methylpropyl)cyclopropane-1-carboxylic acid	IC50	380.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-ethylcyclopropane-1-carboxylic acid	IC50	2520.0 [1]
	Cyclobutyl(2-azaspiro[5.5]undecan-2-yl)methanone	IC50	30000.0 [1]
	(1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-dichlorophenyl)methoxy]-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid	IC50	1900.0 [1]
	(1S,2S,4S,5R,6S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid	IC50	12500.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 55 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Metabotropic glutamate receptor 8 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Dec. 2024, https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-8-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 22). Quest Database™ Metabotropic glutamate receptor 8 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-8-inhibitors-ic50-ki.
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