Metabotropic glutamate receptor 7 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Glutamic acid	Ki	1174897.55 [1], 5400000.0 [2]
	2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-Alanine	IC50	990.0 [1]
	2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-Alanine	Ki	990.0 [1]
	CID 6324634	IC50	300000.0 [1]
	CID 6324634	Ki	300000.0 [1]
	2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acid	IC50	300000.0 [1]
	2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acid	Ki	300000.0 [1]
	2-Methyl-6-(phenylethynyl)pyridine	Ki	100000.0 [1]
	(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acid	Ki	1000000.0 [1]
	(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid	Ki	100000.0 [1]
	Eglumetad	Ki	100000.0 [1]
	(2S)-2-Amino-4-phosphonobutanoic acid	Ki	175000.0 [1]
	(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine	Ki	230000.0 [1]
	(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid	Ki	300000.0 [1]
	CPCCOEt	Ki	100000.0 [1]
	2-Methyl-6-(2-phenylethenyl)pyridine	Ki	100000.0 [1]
	6-Methyl-2-(phenylazo)-3-pyridinol	Ki	100000.0 [1]
	(S)-3,5-Dihydroxyphenylglycine	Ki	1000000.0 [1]
	(RS)-Ppg	Ki	185000.0 [1]
	13-(Dimethylamino)-5-(4-ethylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one	IC50	10000.0 [1]
	CID 10058694	Ki	100000.0 [1]
	N-Pyridin-2-yl-5-thia-3,11,12-triazatricyclo[8.3.0.02,6]trideca-1(10),2(6),3,12-tetraen-4-amine	IC50	10000.0 [1]
	(1r,2s,4r,5r,6r)-2-Amino-4-(1h-1,2,4-Triazol-3-Ylsulfanyl)bicyclo[3.1.0]hexane-2,6-Dicarboxylic Acid	IC50	12500.0 [1]
	1-Adamantyl-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanone	IC50	30000.0 [1]
	(5-Chloro-6-((6-methylpyridin-3-yl)amino)pyridin-3-yl)-((2R)-2-ethylpiperidin-1-yl)methanone	IC50	10000.0 [1]
	N-Methyl-5-(phenylethynyl)pyrimidin-2-amine	IC50	10000.0 [1]
	2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid	Ki	5000000.0 [1]
	N-Pyrimidin-2-yl-5-thia-3,11,12-triazatricyclo[8.3.0.02,6]trideca-1(10),2(6),3,12-tetraen-4-amine	IC50	10000.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-phenylethyl)cyclopropane-1-carboxylic acid	IC50	15350.0 [1]
	2-(m-Tolylethynyl)pyrimidine	IC50	10000.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-butylcyclopropane-1-carboxylic acid	IC50	9420.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-methylcyclopropane-1-carboxylic acid	IC50	23070.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-propylcyclopropane-1-carboxylic acid	IC50	67820.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-nonylcyclopropane-1-carboxylic acid	IC50	7820.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-hexylcyclopropane-1-carboxylic acid	IC50	6250.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-pentylcyclopropane-1-carboxylic acid	IC50	7610.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-methylpropyl)cyclopropane-1-carboxylic acid	IC50	2600.0 [1]
	(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-ethylcyclopropane-1-carboxylic acid	IC50	19660.0 [1]
	N-Pyridin-2-yl-5,6-dihydro-4H-pyrazolo[4,3-e][1,3]benzothiazol-2-amine	IC50	10000.0 [1]
	3-Chloro-5-(7-chloro-1-propylbenzimidazol-2-yl)-N-(6-methylpyridin-3-yl)pyridin-2-amine	IC50	10000.0 [1]
	Cyclobutyl(2-azaspiro[5.5]undecan-2-yl)methanone	IC50	30000.0 [1]
	(1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-dichlorophenyl)methoxy]-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid	IC50	10500.0 [1]
	(1S,2S,4S,5R,6S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid	IC50	12500.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 43 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Metabotropic glutamate receptor 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 19 Feb. 2025, https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-7-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 19). Quest Database™ Metabotropic glutamate receptor 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-7-inhibitors-ic50-ki.
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