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Metabotropic glutamate receptor 7 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Glutamic acidKi1174897.55 [1], 5400000.0 [2]
2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-AlanineIC50990.0 [1]
2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-AlanineKi990.0 [1]
CID 6324634IC50300000.0 [1]
CID 6324634Ki300000.0 [1]
2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acidIC50300000.0 [1]
2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acidKi300000.0 [1]
2-Methyl-6-(phenylethynyl)pyridineKi100000.0 [1]
(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acidKi1000000.0 [1]
(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acidKi100000.0 [1]
EglumetadKi100000.0 [1]
(2S)-2-Amino-4-phosphonobutanoic acidKi175000.0 [1]
(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycineKi230000.0 [1]
(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acidKi300000.0 [1]
CPCCOEtKi100000.0 [1]
2-Methyl-6-(2-phenylethenyl)pyridineKi100000.0 [1]
6-Methyl-2-(phenylazo)-3-pyridinolKi100000.0 [1]
(S)-3,5-DihydroxyphenylglycineKi1000000.0 [1]
(RS)-PpgKi185000.0 [1]
13-(Dimethylamino)-5-(4-ethylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-oneIC5010000.0 [1]
CID 10058694Ki100000.0 [1]
N-Pyridin-2-yl-5-thia-3,11,12-triazatricyclo[8.3.0.02,6]trideca-1(10),2(6),3,12-tetraen-4-amineIC5010000.0 [1]
(1r,2s,4r,5r,6r)-2-Amino-4-(1h-1,2,4-Triazol-3-Ylsulfanyl)bicyclo[3.1.0]hexane-2,6-Dicarboxylic AcidIC5012500.0 [1]
1-Adamantyl-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanoneIC5030000.0 [1]
(5-Chloro-6-((6-methylpyridin-3-yl)amino)pyridin-3-yl)-((2R)-2-ethylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-Methyl-5-(phenylethynyl)pyrimidin-2-amineIC5010000.0 [1]
2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acidKi5000000.0 [1]
N-Pyrimidin-2-yl-5-thia-3,11,12-triazatricyclo[8.3.0.02,6]trideca-1(10),2(6),3,12-tetraen-4-amineIC5010000.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-phenylethyl)cyclopropane-1-carboxylic acidIC5015350.0 [1]
2-(m-Tolylethynyl)pyrimidineIC5010000.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-butylcyclopropane-1-carboxylic acidIC509420.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-methylcyclopropane-1-carboxylic acidIC5023070.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-propylcyclopropane-1-carboxylic acidIC5067820.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-nonylcyclopropane-1-carboxylic acidIC507820.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-hexylcyclopropane-1-carboxylic acidIC506250.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-pentylcyclopropane-1-carboxylic acidIC507610.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-methylpropyl)cyclopropane-1-carboxylic acidIC502600.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-ethylcyclopropane-1-carboxylic acidIC5019660.0 [1]
N-Pyridin-2-yl-5,6-dihydro-4H-pyrazolo[4,3-e][1,3]benzothiazol-2-amineIC5010000.0 [1]
3-Chloro-5-(7-chloro-1-propylbenzimidazol-2-yl)-N-(6-methylpyridin-3-yl)pyridin-2-amineIC5010000.0 [1]
Cyclobutyl(2-azaspiro[5.5]undecan-2-yl)methanoneIC5030000.0 [1]
(1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-dichlorophenyl)methoxy]-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acidIC5010500.0 [1]
(1S,2S,4S,5R,6S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acidIC5012500.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Metabotropic glutamate receptor 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-7-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Metabotropic glutamate receptor 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-7-inhibitors-ic50-ki.
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