Metabotropic glutamate receptor 6 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	(2S,3S)-3-(Carboxymethyl)azetidine-2-carboxylic acid	IC50	300000.0 [1]
	Glutamic acid	Ki	38000.0 [1]
	Miconazole	IC50	6500.0 [1]
	Quisqualic acid	Ki	1000000.0 [1]
	2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline	IC50	74000.0 [1]
	7-Nitro-2,3-Dioxo-2,3-Dihydroquinoxaline-6-Carbonitrile	IC50	23000.0 [1]
	2-Methyl-6-(phenylethynyl)pyridine	Ki	10000.0 [1]
	(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acid	Ki	60000.0 [1]
	(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid	Ki	400.0 [1]
	Eglumetad	Ki	3000.0 [1]
	(2S)-2-Amino-4-phosphonobutanoic acid	Ki	900.0 [1]
	(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine	Ki	5800.0 [1]
	(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid	Ki	110000.0 [1]
	2S,4R-4-Methylglutamate	IC50	4000.0 [1]
	2-Methyl-6-(2-phenylethenyl)pyridine	Ki	100000.0 [1]
	6-Methyl-2-(phenylazo)-3-pyridinol	Ki	100000.0 [1]
	L-2-Aminoadipic acid	Ki	140000.0 [1]
	Benzonitrile, 3-fluoro-5-(2-(2-(fluoromethyl)-4-thiazolyl)ethynyl)-	Ki	10000.0 [1]
	(RS)-Ppg	Ki	4700.0 [1]
	2-Amino-2-(4-phosphonophenyl)propanoic acid	Ki	480000.0 [1]
	CID 10058694	Ki	2400.0 [1]
	Ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate	IC50	750.0 [1]
	(RS)-Apica	Ki	1000000.0 [1]
	2-Amino-4-methyl-5-phenyl-3-thiophenecarbonitrile	IC50	71000.0 [1]
	3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonitrile	Ki	10000.0 [1]
	2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid	Ki	58000.0 [1]
	(2R,4R)-1,4-Diamino-pyrrolidine-2,4-dicarboxylic acid	Ki	1000000.0 [1]
	(1S*,2S*,4S*,5R*,6R*)-2-Amino-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic Acid	IC50	3040.0 [1]
	3,4-Dimethoxy-N-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]benzamide	IC50	10000.0 [1]
	CID 131954513	IC50	10000.0 [1]
	1-Benzyl-APDC	Ki	20000.0 [1]
	Ethyl 2-amino-4,5-diphenylthiophene-3-carboxylate	IC50	4500.0 [1]
	2-Amino-bicyclo[3.2.0]heptane-2,7-dicarboxylic acid	Ki	1000000.0 [1]
	Ethyl 2-amino-5-(4-methoxyphenyl)-4-methylthiophene-3-carboxylate	IC50	8600.0 [1]
	N-[4-Chloro-3-[dideuterio(fluoro)methoxy]phenyl]pyridine-2-carboxamide	IC50	30000.0 [1]
	(2S)-2-Amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-4-yl)-2-methylpropanoic acid	Ki	1000000.0 [1]
	(2S,5S)-2-Aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid	Ki	5300.0 [1]
	2-Isothiocyanato-4-methyl-5-phenylthiophene-3-carboxylate	IC50	3500.0 [1]
	Ethyl 2-chloro-4-methyl-5-phenylthiophene-3-carboxylate	IC50	10000.0 [1]
	Ethyl 2-amino-5-(4-fluorophenyl)-4-methylthiophene-3-carboxylate	IC50	12000.0 [1]
	Ethyl 2-amino-5-(2-chlorophenyl)-4-methylthiophene-3-carboxylate	IC50	5700.0 [1]
	Propyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate	IC50	2400.0 [1]
	Tert-Butyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate	IC50	3600.0 [1]
	(2-Amino-4-methyl-5-phenylthiophen-3-yl)(phenyl)methanone	IC50	10600.0 [1]
	Ethyl 2-(cyanodiazenyl)-4-methyl-5-phenylthiophene-3-carboxylate	IC50	21000.0 [1]
	Ethyl 2-(dimethylaminodiazenyl)-4-methyl-5-phenylthiophene-3-carboxylate	IC50	38000.0 [1]
	Ethyl 4-methyl-2-(morpholinodiazenyl)-5-phenylthiophene-3-carboxylate	IC50	54000.0 [1]
	(1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-dichlorophenyl)methoxy]-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid	IC50	3300.0 [1]
	(1S*,2S*,5R*,6S*)-2-Amino-4-methylenebicyclo[3.1.0]hexane-2,6-dicarboxylic acid	IC50	267.0 [1]
	(1S,2S,4S,5R,6S)-2-Amino-4-azidobicyclo[3.1.0]hexane-2,6-dicarboxylic acid	IC50	1890.0 [1]
	Methyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate	IC50	4100.0 [1]
	CID 9794208	IC50	1380.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 52 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Metabotropic glutamate receptor 6 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-6-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 22). Quest Database™ Metabotropic glutamate receptor 6 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-6-inhibitors-ic50-ki.
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