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Meprin A subunit beta Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
N-Isobutyl-N-[4-methoxyphenylsulfonyl]glycyl hydroxamic acidIC5017100.0 [1]
N-Isobutyl-N-[4-methoxyphenylsulfonyl]glycyl hydroxamic acidKi7400.0 [1]
ActinoninKi2000.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]methyl]benzoic acidIC5057.0 [1], 60.0 [2]
NF449 octasodium saltKi22.0 [1]
N-Hydroxy-N~2~-[(4-Methoxyphenyl)sulfonyl]glycinamideIC509020.0 [1]
2-[Benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxyacetamideIC5040470.0 [1]
2-(Biphenyl-4-ylsulfonamido)-N-hydroxyacetamideIC503850.0 [1]
2-[Phenethyl[(4-methoxyphenyl)sulfonyl]amino]acetohydroximic acidIC5042900.0 [1]
2-[(4-Methoxybenzyl)[(4-methoxyphenyl)sulfonyl]amino]acetohydroximic acidIC5034950.0 [1]
2-[[2-(Hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]acetic acidIC505980.0 [1]
2-[(3-Methylbutyl)[(4-methoxyphenyl)sulfonyl]amino]acetohydroximic acidIC5038800.0 [1]
N-Hydroxy-2-(4-phenoxy-benzenesulfonylamino)-acetamideIC5018800.0 [1]
2-[(4-Fluorophenyl)sulfonylamino]-N-hydroxyacetamideIC5014320.0 [1]
3-[[[3-(Hydroxyamino)-3-oxopropyl]-[(4-methoxyphenyl)methyl]amino]methyl]benzoic acidIC50643.0 [1]
3-[[(4-Cyanophenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50320.0 [1]
3-[[Benzyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC501285.0 [1]
3-[[[(2R)-1-(Hydroxyamino)-1-oxo-3-phenylpropan-2-yl]amino]methyl]benzoic acidIC502910.0 [1]
4-[[(4-Carboxyphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50524.0 [1]
3-[[[(2R)-1-(Hydroxyamino)-1-oxopropan-2-yl]amino]methyl]benzoic acidIC504255.0 [1]
2-[Bis[(4-chloro-2-fluoro-3-hydroxyphenyl)methyl]amino]-N-hydroxyacetamideIC5024.0 [1]
2-[Bis[(4-chloro-2-fluoro-3-methoxyphenyl)methyl]amino]-N-hydroxyacetamideIC5012800.0 [1]
3-[[(3-Fluoro-4-methoxyphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50375.0 [1]
3-[[(3-Carboxyphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC5049.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]-[(3-methoxyphenyl)methyl]amino]methyl]benzoic acidIC50559.0 [1]
3-[[(4-Carboxyphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50207.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50377.0 [1]
3-[[[(2R)-4-Carboxy-1-(hydroxyamino)-1-oxobutan-2-yl]amino]methyl]benzoic acidIC50768.0 [1]
3-[[(4-Fluorophenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50177.0 [1]
3-[[(4-Chlorophenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC5076.0 [1]
3-[[[(2R)-3-Carboxy-1-(hydroxyamino)-1-oxopropan-2-yl]amino]methyl]benzoic acidIC50548.0 [1]
3-[[[(2R)-1-(Hydroxyamino)-3-methyl-1-oxobutan-2-yl]amino]methyl]benzoic acidIC5011850.0 [1]
3-[[[(1R)-2-(Hydroxyamino)-2-oxo-1-phenylethyl]amino]methyl]benzoic acidIC5011650.0 [1]
3-[[1,3-Benzodioxol-5-ylmethyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50285.0 [1]
3-[[[(1S)-2-(Hydroxyamino)-2-oxo-1-phenylethyl]amino]methyl]benzoic acidIC5012150.0 [1]
3-[[[(2S)-4-Carboxy-1-(hydroxyamino)-1-oxobutan-2-yl]amino]methyl]benzoic acidIC50654.0 [1]
2-[Bis[(3-cyanophenyl)methyl]amino]-N-hydroxyacetamideIC5012000.0 [1]
3-[[(3-Carbamoylphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzamideIC5013100.0 [1]
3-[[[4-(Hydroxyamino)-4-oxobutyl]-[(4-methoxyphenyl)methyl]amino]methyl]benzoic acidIC50742.0 [1]
2-[Bis[(4-fluoro-3-hydroxyphenyl)methyl]amino]-N-hydroxyacetamideIC501060.0 [1]
2-[Bis[(3,5-difluoro-4-hydroxyphenyl)methyl]amino]-N-hydroxyacetamideIC50272.0 [1]
2-[Bis[(2-fluoro-3-hydroxyphenyl)methyl]amino]-N-hydroxyacetamideIC502905.0 [1]
2-[Bis[(2,4-difluoro-3-hydroxyphenyl)methyl]amino]-N-hydroxyacetamideIC5023.0 [1]
3-[[[(2S)-1-(Hydroxyamino)-1-oxopropan-2-yl]amino]methyl]benzoic acidIC504200.0 [1]
3-[[[(2S)-1-(Hydroxyamino)-1-oxo-3-phenylpropan-2-yl]amino]methyl]benzoic acidIC5015500.0 [1]
Ethyl 3-[[(3-ethoxycarbonylphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoateIC5094850.0 [1]
3-[[[(2S)-1-(Hydroxyamino)-3-methyl-1-oxobutan-2-yl]amino]methyl]benzoic acidIC5015800.0 [1]
2-[Bis(1,3-benzodioxol-5-ylmethyl)amino]-N-hydroxyacetamideIC506539.0 [1]
2-[Bis[(2,6-difluoro-3-hydroxyphenyl)methyl]amino]-N-hydroxyacetamideIC505515.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]-[(4-methoxyphenyl)methyl]amino]methyl]benzoic acidIC5077.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]-[(4-phenylphenyl)methyl]amino]methyl]benzoic acidIC501280.0 [1]
3-[[[(2S)-3-Carboxy-1-(hydroxyamino)-1-oxopropan-2-yl]amino]methyl]benzoic acidIC501325.0 [1]
2-[Bis[[3-(difluoromethoxy)phenyl]methyl]amino]-N-hydroxyacetamideIC5056950.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]-[(4-methylphenyl)methyl]amino]methyl]benzoic acidIC50386.0 [1]
2-[Bis[(2,4-difluoro-3-methoxyphenyl)methyl]amino]-N-hydroxyacetamideIC5018200.0 [1]
3-[[(2,6-Difluoro-4-methoxyphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50347.0 [1]
2-[(4-Chlorophenyl)sulfonylamino]-N-hydroxyacetamideIC5017170.0 [1]
3-[[(3-Fluoro-4-methoxyphenyl)sulfonyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50650.0 [1]
2-[(3,5-Dichloro-4-hydroxyphenyl)sulfonylamino]-N-hydroxyacetamideIC50430.0 [1]
N-Hydroxy-2-[[4-(4-methoxyphenyl)phenyl]sulfonylamino]acetamideIC504420.0 [1]
2-[Ethyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxyacetamideIC5031200.0 [1]
2-[(5-Fluoro-2-methylphenyl)sulfonylamino]-N-hydroxyacetamideIC5017970.0 [1]
N-Hydroxy-2-[(3-methoxyphenyl)sulfonylamino]acetamideIC5018850.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]-(4-phenylphenyl)sulfonylamino]methyl]benzoic acidIC501080.0 [1]
4-[[3-(Hydroxyamino)-3-oxopropyl]sulfamoyl]benzoic acidIC50340.0 [1]
2-[[4-(4-Chlorophenyl)phenyl]sulfonylamino]-N-hydroxyacetamideIC505650.0 [1]
3-[[(4-Carboxyphenyl)sulfonyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50320.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl-methylamino]acetamideIC5032530.0 [1]
2-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonylamino]-N-hydroxyacetamideIC5010260.0 [1]
3-[[2-(Hydroxyamino)-2-oxoethyl]sulfamoyl]benzoic acidIC50310.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]-[4-(trifluoromethoxy)phenyl]sulfonylamino]methyl]benzoic acidIC50700.0 [1]
2-[(3-Fluoro-4-methoxyphenyl)sulfonylamino]-N-hydroxyacetamideIC506190.0 [1]
2-[(2,4-Dimethylphenyl)sulfonylamino]-N-hydroxyacetamideIC5014770.0 [1]
4-[[[2-(Hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]methyl]benzoic acidIC50980.0 [1]
2-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonylamino)-N-hydroxyacetamideIC507420.0 [1]
Tetrasodium;3-[[4-carboxy-5-hydroxy-6-methyl-3-(phosphonatooxymethyl)pyridin-2-yl]diazenyl]-7-nitronaphthalene-1,5-disulfonateKi8.0 [1]
2-[4-[[2-(Hydroxyamino)-2-oxoethyl]sulfamoyl]phenyl]acetic acidIC505030.0 [1]
2-[[4-(4-Fluorophenyl)phenyl]sulfonylamino]-N-hydroxyacetamideIC507310.0 [1]
3-[(3,5-Dichloro-4-hydroxyphenyl)sulfonylamino]-N-hydroxypropanamideIC50400.0 [1]
2-[2-Bicyclo[2.2.1]heptanylmethyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxyacetamideIC5043870.0 [1]
3-[[(3-Carboxyphenyl)sulfonyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC5060.0 [1]
3-[[1,3-Benzodioxol-5-ylsulfonyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC50270.0 [1]
N-Hydroxy-2-[(2-methoxy-4-methylphenyl)sulfonylamino]acetamideIC5025700.0 [1]
3-[[(4-Fluorophenyl)sulfonyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acidIC501060.0 [1]
3-[[3-(Hydroxyamino)-3-oxopropyl]sulfamoyl]benzoic acidIC50220.0 [1]
3-[[2-(Hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]propanoic acidIC502550.0 [1]
4-[[2-(Hydroxyamino)-2-oxoethyl]sulfamoyl]benzoic acidIC50410.0 [1]
3-[[[2-(Hydroxyamino)-2-oxoethyl]-[(3-propoxyphenyl)methyl]amino]methyl]benzoic acidIC502250.0 [1]
2-[1,3-Benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxyacetamideIC501930.0 [1]
2-[(3,4-Dimethoxyphenyl)sulfonylamino]-N-hydroxyacetamideIC5026900.0 [1]
2-[Butyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxyacetamideIC5037500.0 [1]
Items per page: 1 - 10 of 91
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References

This online tool may be cited as follows

MLA

"Quest Database™ Meprin A subunit beta Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/meprin-a-subunit-beta-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Meprin A subunit beta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/meprin-a-subunit-beta-inhibitors-ic50-ki.
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