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Membrane metallo-endopeptidase-like 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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(3R)-4-[4-(3-Chlorophenyl)phenyl]-3-[(2-oxo-3H-1,3,4-oxadiazole-5-carbonyl)amino]butanoic acidIC500.5 [1]
(3R)-4-[4-(3-Chlorophenyl)phenyl]-3-[(2-ethyl-1,3-oxazole-5-carbonyl)amino]butanoic acidIC502.7 [1]
4-[[(2R)-1-Carboxy-3-[4-(2-methoxyphenyl)phenyl]propan-2-yl]amino]-4-oxobutanoic acidIC504.0 [1]
(R)-4-(Biphenyl-4-yl)-3-(3-carboxypropanamido)butanoic acidIC5038.0 [1]
(R)-4-(1-Carboxy-3-(5'-fluoro-2'-methoxybiphenyl-4-yl)propan-2-ylamino)-4-oxobutanoic acidIC502.3 [1]
4-[[(2R)-1-Carboxy-3-[4-(5-chloro-2-methoxyphenyl)phenyl]propan-2-yl]amino]-4-oxobutanoic acidIC500.7 [1]
(R)-4-(1-Carboxy-3-(3'-chlorobiphenyl-4-yl)propan-2-ylamino)-4-oxobutanoic acidIC500.2 [1], 1.1 [2]
4-[[(2R)-1-Carboxy-3-[4-(3-fluorophenyl)phenyl]propan-2-yl]amino]-4-oxobutanoic acidIC507.0 [1]
(3R)-3-[(2-Oxo-1H-pyrimidine-5-carbonyl)amino]-4-(4-phenylphenyl)butanoic acidIC503.0 [1]
(R)-3-(3-Carboxymethyl-ureido)-4-(3'-chloro-biphenyl-4-yl)-butyric acidIC500.8 [1]
(R)-3-(4-Butoxy-4-oxobutanamido)-4-(3'-chlorobiphenyl-4-yl)butanoic acidIC5015.0 [1], 18.0 [2]
(3R)-4-[4-(3-Chlorophenyl)phenyl]-3-[(5-ethoxy-5-oxopentanoyl)amino]butanoic acidIC5015.0 [1]
4-[[(2R)-1-Carboxy-3-[4-(3-chlorophenyl)phenyl]propan-2-yl]amino]-2,2,3,3-tetrafluoro-4-oxobutanoic acidIC500.5 [1]
(R)-3-(Biphenyl-4-ylmethyl)-4-(2-carboxyethylamino)-4-oxobutanoic acidIC5075.0 [1]
6-[[(2R)-1-Carboxy-3-(4-phenylphenyl)propan-2-yl]carbamoyl]pyrimidine-4-carboxylic acidIC5067.0 [1]
(3R)-4-[4-(5-Fluoro-2-methoxyphenyl)phenyl]-3-[(3-oxo-1,2-oxazole-5-carbonyl)amino]butanoic acidIC500.7 [1]
(3R)-4-[4-(3-Chlorophenyl)phenyl]-3-(2H-tetrazole-5-carbonylamino)butanoic acidIC501.2 [1]
(R)-4-Biphenyl-4-yl-3-[(1H-tetrazole-5-carbonyl)-amino]-butyric acidIC5056.0 [1]
5-[[(2R,4S)-4-Carboxy-1-(4-phenylphenyl)pentan-2-yl]carbamoyl]-1H-imidazole-2-carboxylic acidIC507.3 [1]
6-[[(2R,4S)-4-Carboxy-1-(4-phenylphenyl)pentan-2-yl]carbamoyl]pyrimidine-4-carboxylic acidIC501.0 [1]
(2S,4R)-2-Methyl-4-[4-(2-methyl-1,3-benzothiazol-6-yl)butanoylamino]-5-(4-phenylphenyl)pentanoic acidIC50250.0 [1]
3-[[(2S,4R)-4-Carboxy-1-(4-phenylphenyl)pentan-2-yl]carbamoyl]benzoic acidIC50283.0 [1]
(2R,4S)-4-[(3-Carboxy-3-methylbutanoyl)amino]-2-methyl-5-(4-phenylphenyl)pentanoic acidIC50267.0 [1]
(S)-2-[(S)-2-(3'-Chloro-biphenyl-4-yl)-1-(1H-tetrazol-5-ylcarbamoyl)-ethylamino]-propionic acidIC500.09 [1]
(S)-2-[(S)-2-(2',5'-Dichloro-biphenyl-4-yl)-1-(1H-tetrazol-5-ylcarbamoyl)-ethylamino]-propionic acidIC500.3 [1]
(2S)-2-[[(2S)-3-[4-(3-Chlorophenyl)phenyl]-1-[(1-methyltetrazol-5-yl)amino]-1-oxopropan-2-yl]amino]propanoic acidIC5091.0 [1]
(2S)-2-[[(2S)-3-[4-(3-Chlorophenyl)phenyl]-1-oxo-1-(2H-tetrazol-5-ylamino)propan-2-yl]amino]butanoic acidIC500.2 [1]
(2R,4S)-4-(3-Carboxy-propionylamino)-5-(3'-chloro-biphenyl-4-yl)-2-methyl-pentanoic acidIC500.3 [1]
(2S)-2-[[(2S)-3-[4-(3-Chlorophenyl)phenyl]-1-oxo-1-[(3-oxo-1,2-oxazol-5-yl)amino]propan-2-yl]amino]propanoic acidIC502.4 [1]
(3R)-3-[[(Z)-4-Amino-2-hydroxy-4-oxobut-2-enoyl]amino]-4-[4-(3-chlorophenyl)phenyl]butanoic acidIC500.07 [1]
4-[[(2R)-1-Carboxy-3-[4-(2,5-dichlorophenyl)phenyl]propan-2-yl]amino]-4-oxobutanoic acidIC500.2 [1]
(3R)-4-[4-(5-Chloro-2-fluorophenyl)phenyl]-3-[(2-ethyl-1,3-oxazole-5-carbonyl)amino]butanoic acidIC500.4 [1]
6-((1S,3R)-1-Biphenyl-4-ylmethyl-3-carboxy-butylcarbamoyl)-4-oxo-4H-pyran-2-carboxylic acidIC50350.0 [1]
(2S,4S)-5-[4-(3-Chlorophenyl)phenyl]-2-methyl-4-[(3-oxo-1,2-oxazole-5-carbonyl)amino]pentanoic acidIC500.3 [1]
1-((1S,3R)-1-Biphenyl-4-ylmethyl-3-carboxy-butylcarbamoyl)-1H-pyrazole-3-carboxylic acidIC50142.0 [1]
(2R,4S)-5-Biphenyl-4-yl-2-methyl-4-[(1H-tetrazole-5-carbonyl)-amino]-pentanoic acidIC5014.0 [1]
(2R,4S)-4-(Carboxymethylcarbamoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acidIC5093.0 [1]
(2R,4S)-5-[4-(3-Chlorophenyl)phenyl]-2-methyl-4-[(3-oxo-1,2-oxazole-5-carbonyl)amino]pentanoic acidIC500.03 [1]
(2S)-1-[[(2S,4R)-4-Carboxy-1-(4-phenylphenyl)pentan-2-yl]carbamoyl]pyrrolidine-2-carboxylic acidIC50450.0 [1]
(3R)-4-[4-(3-Chlorophenyl)phenyl]-3-[(3-oxo-1,2-oxazole-5-carbonyl)amino]butanoic acidIC500.07 [1]
4-[4-(3-Chlorophenyl)phenyl]-3-[[4-(2,3-dihydro-1H-inden-5-yloxy)-4-oxobutanoyl]amino]butanoic acidIC5015.0 [1]
(2S)-2-[[(2S)-1-Oxo-3-(4-phenylphenyl)-1-(2H-tetrazol-5-ylamino)propan-2-yl]amino]propanoic acidIC5011.0 [1]
(2S)-2-[[(2S)-3-[4-(3-Chlorophenyl)phenyl]-1-oxo-1-(2H-tetrazol-5-ylamino)propan-2-yl]amino]-4-phenylbutanoic acidIC500.2 [1]
Benzyl 1-[2-[[(2R)-4-ethoxy-4-oxo-1-(4-phenylphenyl)butan-2-yl]amino]-2-oxoethyl]pyrrolidine-2-carboxylateIC5018.0 [1]
Items per page: 1 - 10 of 44
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References

This online tool may be cited as follows

MLA

"Quest Database™ Membrane metallo-endopeptidase-like 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/membrane-metallo-endopeptidase-like-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Membrane metallo-endopeptidase-like 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/membrane-metallo-endopeptidase-like-1-inhibitors-ic50-ki.
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