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Matrix metalloproteinase 17 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
4-{[1-Methyl-2,4-Dioxo-6-(3-Phenylprop-1-Yn-1-Yl)-1,4-Dihydroquinazolin-3(2h)-Yl]methyl}benzoic AcidIC5030000.0 [1]
Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-CarboxylateIC5030000.0 [1], 100000.0 [2]
IlomastatIC503.4 [1]
(2S)-2-[[8-(Methoxycarbonylamino)dibenzofuran-3-yl]sulfonylamino]-3-methylbutanoic acidIC5025.0 [1]
N-Hydroxy-N-[1-[1-(2-methylpropyl)piperidin-4-ylidene]-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylpropan-2-yl]formamideIC504000.0 [1]
N-Hydroxy-N-[1-(4-hydroxyiminocyclohexylidene)-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylpropan-2-yl]formamideIC503000.0 [1]
N-Hydroxy-N-[1-(4-methylidenecyclohexyl)-2-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylethyl]formamideIC502000.0 [1]
N-Hydroxy-N-[1-[1-(2-methylpropyl)piperidin-4-yl]-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylpropan-2-yl]formamideIC50350.0 [1]
(2R)-N-[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamideIC505.7 [1]
(2R)-N-[(2S)-1-[[(2S)-1-Amino-6-[(4-fluorobenzoyl)amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamideIC5024.7 [1]
[[(3R)-3-[[(2S)-1-[[(2S)-1-Amino-6-[(4-fluorobenzoyl)amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-5-methylhexanoyl]amino] 4-fluorobenzoateIC503260.0 [1]
N-Hydroxy-N-[1-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonyl-3-(oxan-4-ylidene)propan-2-yl]formamideIC503000.0 [1]
N-Hydroxy-N-[2-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonyl-1-(4-oxocyclohexyl)ethyl]formamideIC50600.0 [1]
[4-[2-[Formyl(hydroxy)amino]-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylpropylidene]piperidin-1-yl] 2,2-dimethylpropanoateIC50550.0 [1]
N-Hydroxy-N-[1-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonyl-3-(thian-4-ylidene)propan-2-yl]formamideIC504000.0 [1]
N-[1-(1,4-Dioxaspiro[4.5]decan-8-yl)-2-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylethyl]-N-hydroxyformamideIC50220.0 [1]
N-Hydroxy-N-[1-(4-hydroxyiminocyclohexyl)-2-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylethyl]formamideIC50500.0 [1]
N-Hydroxy-N-[1-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonyl-3-(4-oxocyclohexyl)propan-2-yl]formamideIC50350.0 [1]
N-[1-(1,4-Dioxaspiro[4.5]decan-8-yl)-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylpropan-2-yl]-N-hydroxyformamideIC501100.0 [1]
N-Hydroxy-N-[1-(4-hydroxyiminocyclohexyl)-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylpropan-2-yl]formamideIC50330.0 [1]
N-Hydroxy-N-[1-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonyl-3-(4-oxocyclohexylidene)propan-2-yl]formamideIC502500.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Matrix metalloproteinase 17 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/matrix-metalloproteinase-17-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Matrix metalloproteinase 17 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/matrix-metalloproteinase-17-inhibitors-ic50-ki.
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