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Matrix metalloproteinase 15 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
IlomastatIC506.0 [1]
CID 6914621Ki3997.0 [1]
(8S,11R,12S)-12-N-Hydroxy-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi2000.0 [1]
N-[4-[2-(Hydroxyamino)-2-oxoethyl]oxan-4-yl]-4-[(2-methylquinolin-4-yl)methoxy]benzamideKi7088.0 [1]
(3R,4R)-N-Hydroxy-4-[[4-[[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]methyl]benzoyl]amino]oxane-3-carboxamideKi7088.0 [1]
MarimastatIC5010000.0 [1]
(3R,4R)-N-Hydroxy-4-[[4-[[2-(trifluoromethyl)benzimidazol-1-yl]methyl]benzoyl]amino]oxane-3-carboxamideKi10000.0 [1]
N,6-Dihydroxy-2-(4-nitrophenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC50126.0 [1]
(2R)-N-Hydroxy-2-methyl-2-methylsulfonyl-4-(4-phenylphenyl)butanamideKi10000.0 [1]
CID 10160968Ki7088.0 [1]
(6S,7R,10S)-6-N-Hydroxy-10-N-[2-(methylamino)-2-oxoethyl]-7-(2-methylpropyl)-8-oxo-2-oxa-9-azabicyclo[10.2.2]hexadeca-1(14),12,15-triene-6,10-dicarboxamideKi20.0 [1]
6-(Benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC504.0 [1]
(3S,4S)-N-Hydroxy-4-[[4-[(2-methylquinolin-4-yl)methoxy]benzoyl]amino]-1-prop-2-ynylpyrrolidine-3-carboxamideKi7100.0 [1]
4-[[5-[2-[(4-Fluorophenyl)methylcarbamoyl]-6-methylpyridin-4-yl]tetrazol-2-yl]methyl]cyclohexane-1-carboxylic acidKi25000.0 [1]
6-(Benzyloxy)-N-hydroxy-2-tosyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5044.0 [1]
6-(Benzyloxy)-N-hydroxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5017.0 [1]
N,6-Dihydroxy-2-tosyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5019.0 [1]
2-(Benzenesulfonyl)-N,6-dihydroxy-3,4-dihydro-1H-isoquinoline-1-carboxamideIC50218.0 [1]
N,6-Dihydroxy-7-methoxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC506.0 [1]
N,6-Dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5029.0 [1]
2-(2,5-Dichlorophenylsulfonyl)-N,6-dihydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC501789.0 [1]
(6S,7S)-N-Hydroxy-5-methyl-6-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbonyl]-5-azaspiro[2.5]octane-7-carboxamideIC505000.0 [1]
(8S,11R,12S)-12-N-Hydroxy-11-(2-methylpropyl)-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi71.0 [1]
(8S,11R,12S)-12-N-Hydroxy-2,10-dioxo-8-N-(2-oxo-2-piperazin-1-ylethyl)-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi2000.0 [1]
Tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[[4-[(2-methylbenzimidazol-1-yl)methyl]benzoyl]amino]pyrrolidine-1-carboxylateKi7088.0 [1]
Tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[[4-[(2-methylsulfanylbenzimidazol-1-yl)methyl]benzoyl]amino]pyrrolidine-1-carboxylateKi7088.0 [1]
Tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[[4-[(2-propan-2-ylbenzimidazol-1-yl)methyl]benzoyl]amino]pyrrolidine-1-carboxylateKi7088.0 [1]
N-[(2R,6S)-4-[2-(Hydroxyamino)-2-oxoethyl]-2,6-dimethylpiperidin-4-yl]-4-[(2-methylquinolin-4-yl)methoxy]benzamideKi1700.0 [1]
(8S,11R,12S)-8-N-(2-Amino-2-oxoethyl)-12-N-hydroxy-2,10-dioxo-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi2000.0 [1]
3-(4-(2-Phenylethynyl)benzoyl)pentanoic acidIC5013940.0 [1]
(8S,11R,12S)-11-[[4-[3,5-Bis(trifluoromethyl)phenyl]phenyl]methyl]-12-N-hydroxy-2,10-dioxo-8-N-(2-oxo-2-piperazin-1-ylethyl)-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi2000.0 [1]
(3R,4R)-N-Hydroxy-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)-tetrahydro-2H-pyran-3-carboxamideIC507000.0 [1]
2-(4-Aminophenyl)sulfonyl-N,6-dihydroxy-3,4-dihydro-1H-isoquinoline-1-carboxamideIC50385.0 [1]
2-(2,5-Dichlorophenyl)sulfonyl-N-hydroxy-6-phenylmethoxy-3,4-dihydro-1H-isoquinoline-1-carboxamideIC507303.0 [1]
N,6-Dihydroxy-2-(4-methoxyphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-1-carboxamideIC50621.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Matrix metalloproteinase 15 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/matrix-metalloproteinase-15-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ Matrix metalloproteinase 15 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/matrix-metalloproteinase-15-inhibitors-ic50-ki.
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