MAP/microtubule affinity-regulating kinase 4 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	7-[(1S)-1-(4-Fluorophenyl)ethyl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one	IC50	10000.0 [1]
	7-[(2R)-Butan-2-yl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one	IC50	5910.0 [1]
	7-Cyclohexyl-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one	IC50	5990.0 [1]
	5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamide	IC50	10000.0 [1]
	6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one	IC50	10000.0 [1]
	2-Anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one	IC50	21.0 [1]
	2-Anilino-7-[(1R)-2,2-difluoro-1-phenylethyl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one	IC50	10000.0 [1]
	2-Anilino-5,5-dimethyl-7-phenylpyrrolo[2,3-d]pyrimidin-6-one	IC50	10000.0 [1]
	2-Anilino-7-cyclohexyl-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one	IC50	8600.0 [1]
	7-Cyclohexyl-5,5-dimethyl-N-phenyl-6H-pyrrolo[2,3-d]pyrimidin-2-amine	IC50	10000.0 [1]
	7-[(1S)-1-(3-Hydroxyphenyl)ethyl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one	IC50	270.0 [1]
	7-[(1S)-4-Amino-2,3-dihydro-1H-inden-1-yl]-2-anilino-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one	IC50	450.0 [1]
	2-Anilino-5,5-dimethyl-7-[(2S)-3-methylbutan-2-yl]pyrrolo[2,3-d]pyrimidin-6-one	IC50	10000.0 [1]
	2-Anilino-5,5-dimethyl-6-(1-methylpyrazol-4-yl)pyrrolo[3,4-d]pyrimidin-7-one	IC50	10000.0 [1]
	7-Cyclohexyl-5,5-dimethyl-2-(3-piperazin-1-ylanilino)pyrrolo[2,3-d]pyrimidin-6-one	IC50	920.0 [1]
	5,5-Dimethyl-7-(2-phenylpropan-2-yl)-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one	IC50	3760.0 [1]
	2-Anilino-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one	IC50	10000.0 [1]
	7-[(1S)-2,3-Dihydro-1H-inden-1-yl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one	IC50	520.0 [1]
	N-[(1S)-1-(2-Anilino-5,5-dimethyl-6-oxopyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydro-1H-inden-4-yl]methanesulfonamide	IC50	180.0 [1]
	2-(Furan-2-yl)-3-(4-methoxyanilino)chromen-4-one	IC50	5560.0 [1]
	6,8-Dichloro-2-(furan-2-yl)-3-(4-nitroanilino)chromen-4-one	IC50	2120.0 [1]
	6,8-Dichloro-2-(furan-2-yl)-3-(4-iodoanilino)chromen-4-one	IC50	1980.0 [1]
	5,5-Dimethyl-7-[(1S)-1-phenylethyl]-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one	IC50	2750.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 23 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ MAP/microtubule affinity-regulating kinase 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/map-microtubule-affinity-regulating-kinase-4-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ MAP/microtubule affinity-regulating kinase 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/map-microtubule-affinity-regulating-kinase-4-inhibitors-ic50-ki.
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