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Mannose-6-phosphate isomerase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
2-[4-(2,4-Dichloro-phenoxy)-butyrylamino]-indan-2-carboxylic acid amideIC5040000.0 [1]
2-[4-(2,4-Dichloro-phenoxy)-butyrylamino]-indan-2-carboxylic acid amideKi4000.0 [1]
2-[4-(3,4-Dichlorophenyl)sulfanylbutanoylamino]-N-hydroxy-1,3-dihydroindene-2-carboxamideIC506000.0 [1]
2-[4-(3,4-Dichlorophenyl)sulfanylbutanoylamino]-N-hydroxy-1,3-dihydroindene-2-carboxamideKi4000.0 [1], 26000.0 [2]
1,2-Benzisothiazol-3(2H)-one, 2-phenyl-IC506400.0 [1]
2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-oneIC503900.0 [1], 5200.0 [2]
Methyl 3-(3-oxo-1,2-benzothiazol-2-yl)benzoateIC504900.0 [1]
2-(3-Chlorophenyl)-1,2-benzothiazol-3-oneIC504800.0 [1]
Ethyl 4-(3-oxo-1,2-benzisothiazol-2(3H)-yl)benzoateIC507200.0 [1], 23000.0 [2]
6-Fluoro-2-(4-methoxyphenyl)-1,2-benzothiazol-3-oneIC501000.0 [1], 3100.0 [2]
2-(2,5-Dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-oneIC501000.0 [1], 1100.0 [2]
2-(m-Tolyl)-1,2-benzothiazol-3-oneIC506000.0 [1]
2-(2,5-Dimethylphenyl)-1,2-benzothiazol-3-oneIC506600.0 [1]
2-[4-(Dimethylamino)phenyl]-1,2-benzothiazol-3-oneIC501900.0 [1], 8400.0 [2]
(4,5,6-Trihydroxyoxan-3-yl) dihydrogen phosphateIC50100000.0 [1]
(2,3-Dihydroxy-4-oxobutyl) dihydrogen phosphateIC50100000.0 [1]
2-[[3-(3-Oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acidIC50710.0 [1]
2-(4-Chlorophenyl)-1,2-benzothiazol-3-oneIC501900.0 [1]
2-(4-Fluorophenyl)-1,2-benzothiazol-3-oneIC503400.0 [1]
3-(3-Oxo-1,2-benzothiazol-2-yl)benzoic acidIC503300.0 [1]
5-Fluoro-2-(4-methoxyphenyl)-1,2-benzothiazol-3-oneIC501000.0 [1]
6-Fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-oneIC502900.0 [1]
5-Fluoro-2-phenyl-1,2-benzothiazol-3-oneIC501300.0 [1]
2-(2-Morpholino-5-morpholinosulfonyl-phenyl)-1,2-benzothiazol-3-oneIC502600.0 [1]
2-(5-Morpholin-4-ylsulfonyl-2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-oneIC507500.0 [1]
2-[4-Methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-oneIC503100.0 [1]
2-(2,5-Dimethylphenyl)-5-fluoranyl-1,2-benzothiazol-3-oneIC501900.0 [1]
5-Fluoro-2-(4-fluorophenyl)-1,2-benzothiazol-3-oneIC503600.0 [1]
N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamideIC502800.0 [1]
6-Fluoro-2-phenyl-1,2-benzothiazol-3-oneIC501300.0 [1]
N,N-Diethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamideIC5050000.0 [1]
2-(4-Chlorophenyl)-5-fluoro-1,2-benzothiazol-3-oneIC501800.0 [1]
2-[3-(Trifluoromethyl)phenyl]-1,2-benzothiazol-3-oneIC503400.0 [1]
2-[4-(2,4-Dichloro-phenylamino)-butyrylamino]-indan-2-carboxylic acid amideIC5050000.0 [1]
2-[4-(2,4-Dichloro-phenylsulfanyl)-butyrylamino]-indan-2-carboxylic acid amideIC5014000.0 [1]
6-Fluoro-2-(4-fluorophenyl)-1,2-benzothiazol-3-oneIC503600.0 [1]
2-[4-(Trifluoromethyl)phenyl]-1,2-benzothiazol-3-oneIC5020000.0 [1]
2-(2,5-Dimethylphenyl)-1H-indazol-3-oneIC5010000.0 [1]
2-(2,3-Dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-oneIC509900.0 [1]
N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzamideIC5062000.0 [1]
3-(3-Oxo-1,2-benzothiazol-2-yl)-N-(phenylmethyl)benzamideIC502300.0 [1]
2-(3-Methoxyphenyl)-1,2-benzothiazol-3-oneIC503700.0 [1]
2-(4-Chloro-3-morpholin-4-ylsulfonylphenyl)-1,2-benzothiazol-3-oneIC508600.0 [1]
2-(2,5-Dimethylphenyl)isoindolin-1-oneIC5010000.0 [1]
2-[3-(Dimethylamino)phenyl]-1,2-benzothiazol-3-oneIC508500.0 [1]
2-(3-Iodophenyl)-1,2-benzothiazol-3-oneIC504300.0 [1]
2-(Naphthalen-2-yl)-1,2-benzothiazol-3(2H)-oneIC509400.0 [1]
2-(4-Tert-butylphenyl)-1,2-benzothiazol-3-oneIC505000.0 [1]
5-Fluoro-2-(2-fluorophenyl)-1,2-benzothiazol-3-oneIC504300.0 [1]
5-Fluoro-2-(3-fluorophenyl)-1,2-benzothiazol-3-oneIC508300.0 [1]
2-Phenyl-2,3-dihydro-1-benzothiophen-3-oneIC5010000.0 [1]
2-(3-Chloro-4-fluorophenyl)-2,3-dihydro-1,2-benzothiazol-3-oneIC5050000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Mannose-6-phosphate isomerase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/mannose-6-phosphate-isomerase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Mannose-6-phosphate isomerase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mannose-6-phosphate-isomerase-inhibitors-ic50-ki.
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