Mannose-6-phosphate isomerase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-[4-(2,4-Dichloro-phenoxy)-butyrylamino]-indan-2-carboxylic acid amide	IC50	40000.0 [1]
	2-[4-(2,4-Dichloro-phenoxy)-butyrylamino]-indan-2-carboxylic acid amide	Ki	4000.0 [1]
	2-[4-(3,4-Dichlorophenyl)sulfanylbutanoylamino]-N-hydroxy-1,3-dihydroindene-2-carboxamide	IC50	6000.0 [1]
	2-[4-(3,4-Dichlorophenyl)sulfanylbutanoylamino]-N-hydroxy-1,3-dihydroindene-2-carboxamide	Ki	4000.0 [1], 26000.0 [2]
	1,2-Benzisothiazol-3(2H)-one, 2-phenyl-	IC50	6400.0 [1]
	2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-one	IC50	3900.0 [1], 5200.0 [2]
	Methyl 3-(3-oxo-1,2-benzothiazol-2-yl)benzoate	IC50	4900.0 [1]
	2-(3-Chlorophenyl)-1,2-benzothiazol-3-one	IC50	4800.0 [1]
	Ethyl 4-(3-oxo-1,2-benzisothiazol-2(3H)-yl)benzoate	IC50	7200.0 [1], 23000.0 [2]
	6-Fluoro-2-(4-methoxyphenyl)-1,2-benzothiazol-3-one	IC50	1000.0 [1], 3100.0 [2]
	2-(2,5-Dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-one	IC50	1000.0 [1], 1100.0 [2]
	2-(m-Tolyl)-1,2-benzothiazol-3-one	IC50	6000.0 [1]
	2-(2,5-Dimethylphenyl)-1,2-benzothiazol-3-one	IC50	6600.0 [1]
	2-[4-(Dimethylamino)phenyl]-1,2-benzothiazol-3-one	IC50	1900.0 [1], 8400.0 [2]
	(4,5,6-Trihydroxyoxan-3-yl) dihydrogen phosphate	IC50	100000.0 [1]
	(2,3-Dihydroxy-4-oxobutyl) dihydrogen phosphate	IC50	100000.0 [1]
	2-[[3-(3-Oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acid	IC50	710.0 [1]
	2-(4-Chlorophenyl)-1,2-benzothiazol-3-one	IC50	1900.0 [1]
	2-(4-Fluorophenyl)-1,2-benzothiazol-3-one	IC50	3400.0 [1]
	3-(3-Oxo-1,2-benzothiazol-2-yl)benzoic acid	IC50	3300.0 [1]
	5-Fluoro-2-(4-methoxyphenyl)-1,2-benzothiazol-3-one	IC50	1000.0 [1]
	6-Fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one	IC50	2900.0 [1]
	5-Fluoro-2-phenyl-1,2-benzothiazol-3-one	IC50	1300.0 [1]
	2-(2-Morpholino-5-morpholinosulfonyl-phenyl)-1,2-benzothiazol-3-one	IC50	2600.0 [1]
	2-(5-Morpholin-4-ylsulfonyl-2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-one	IC50	7500.0 [1]
	2-[4-Methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one	IC50	3100.0 [1]
	2-(2,5-Dimethylphenyl)-5-fluoranyl-1,2-benzothiazol-3-one	IC50	1900.0 [1]
	5-Fluoro-2-(4-fluorophenyl)-1,2-benzothiazol-3-one	IC50	3600.0 [1]
	N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide	IC50	2800.0 [1]
	6-Fluoro-2-phenyl-1,2-benzothiazol-3-one	IC50	1300.0 [1]
	N,N-Diethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide	IC50	50000.0 [1]
	2-(4-Chlorophenyl)-5-fluoro-1,2-benzothiazol-3-one	IC50	1800.0 [1]
	2-[3-(Trifluoromethyl)phenyl]-1,2-benzothiazol-3-one	IC50	3400.0 [1]
	2-[4-(2,4-Dichloro-phenylamino)-butyrylamino]-indan-2-carboxylic acid amide	IC50	50000.0 [1]
	2-[4-(2,4-Dichloro-phenylsulfanyl)-butyrylamino]-indan-2-carboxylic acid amide	IC50	14000.0 [1]
	6-Fluoro-2-(4-fluorophenyl)-1,2-benzothiazol-3-one	IC50	3600.0 [1]
	2-[4-(Trifluoromethyl)phenyl]-1,2-benzothiazol-3-one	IC50	20000.0 [1]
	2-(2,5-Dimethylphenyl)-1H-indazol-3-one	IC50	10000.0 [1]
	2-(2,3-Dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-one	IC50	9900.0 [1]
	N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzamide	IC50	62000.0 [1]
	3-(3-Oxo-1,2-benzothiazol-2-yl)-N-(phenylmethyl)benzamide	IC50	2300.0 [1]
	2-(3-Methoxyphenyl)-1,2-benzothiazol-3-one	IC50	3700.0 [1]
	2-(4-Chloro-3-morpholin-4-ylsulfonylphenyl)-1,2-benzothiazol-3-one	IC50	8600.0 [1]
	2-(2,5-Dimethylphenyl)isoindolin-1-one	IC50	10000.0 [1]
	2-[3-(Dimethylamino)phenyl]-1,2-benzothiazol-3-one	IC50	8500.0 [1]
	2-(3-Iodophenyl)-1,2-benzothiazol-3-one	IC50	4300.0 [1]
	2-(Naphthalen-2-yl)-1,2-benzothiazol-3(2H)-one	IC50	9400.0 [1]
	2-(4-Tert-butylphenyl)-1,2-benzothiazol-3-one	IC50	5000.0 [1]
	5-Fluoro-2-(2-fluorophenyl)-1,2-benzothiazol-3-one	IC50	4300.0 [1]
	5-Fluoro-2-(3-fluorophenyl)-1,2-benzothiazol-3-one	IC50	8300.0 [1]
	2-Phenyl-2,3-dihydro-1-benzothiophen-3-one	IC50	10000.0 [1]
	2-(3-Chloro-4-fluorophenyl)-2,3-dihydro-1,2-benzothiazol-3-one	IC50	50000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 52 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Mannose-6-phosphate isomerase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/mannose-6-phosphate-isomerase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 21). Quest Database™ Mannose-6-phosphate isomerase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mannose-6-phosphate-isomerase-inhibitors-ic50-ki.
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