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Malate dehydrogenase, mitochondrial Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
CID 16124726IC506300.0 [1]
CID 16124726Ki1900.0 [1]
2',6'-Dichloro-4-((2-chlorophenyl)thio)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-oneIC5010000.0 [1], 100000.0 [2]
Methyl 3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoateIC501060.0 [1]
Methyl 3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoateKi950.0 [1]
Prop-2-ynyl 3-[[2-[4-(1-adamantyl)-2-[3-(trifluoromethyl)diazirin-3-yl]phenoxy]acetyl]amino]-4-hydroxybenzoateIC505500.0 [1]
Prop-2-ynyl 3-[[2-[4-(1-adamantyl)-2-[3-(trifluoromethyl)diazirin-3-yl]phenoxy]acetyl]amino]-4-hydroxybenzoateKi4300.0 [1]
LevothyroxineIC5043600.0 [1]
7-Chloro-4-hydroxyquinoline-3-carboxylic acidIC503630780.55 [1]
4-Oxo-1H-quinoline-3,7-dicarboxylic acidIC501071519.31 [1]
3-Quinolinecarboxylic acid, 4-hydroxy-7-(methylsulfonyl)-IC50660693.45 [1]
3-Quinolinecarboxylic acid, 7-(dimethylamino)-1,4-dihydro-4-oxo-IC50478630.09 [1]
4-Hydroxy-7-benzyloxyquinoline-3-carboxylic acidIC5032359.37 [1]
7-Fluoro-4-hydroxyquinoline-3-carboxylic acidIC5010471285.48 [1]
4-Oxo-7-sulfo-1H-quinoline-3-carboxylic acidIC502137962.09 [1]
4-Oxo-7-sulfamoyl-1H-quinoline-3-carboxylic acidIC50954992.59 [1]
7-Acetyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acidIC50912010.84 [1]
4-Hydroxy-7-nitroquinoline-3-carboxylic acidIC501905460.72 [1]
Paullone Analog 46IC502400.0 [1]
4,7-Dihydroxy-3-quinolinecarboxylic acidIC50489778.82 [1]
2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)acetamideIC5010000.0 [1]
2-[4-[2-[5-Hydroxy-2-[(4-methoxyphenyl)methylcarbamoyl]-4-oxochromen-7-yl]oxyethyl]-2-methoxyanilino]-2-oxoacetic acidIC508480.0 [1]
7-[(3,4-Dichlorophenyl)methoxy]-4-oxo-1H-quinoline-3-carboxylic acidIC504786.3 [1]
3-Quinolinecarboxylic acid, 7-(aminocarbonyl)-1,4-dihydro-4-oxo-IC50741310.24 [1]
Methyl 3-[[2-(4-propylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
Prop-2-ynyl 4-hydroxy-3-[(2-phenoxyacetyl)amino]benzoateIC5020000.0 [1]
2-[4-(1-Adamantyl)phenoxy]-N-[3-(4-prop-2-ynoxybenzoyl)phenyl]acetamideIC5020000.0 [1]
(E)-3-[4-(1-Adamantyl)phenoxy]-N-[3-(4-prop-2-ynoxybenzoyl)phenyl]prop-2-enamideIC5020000.0 [1]
[4-[3-(Trifluoromethyl)diazirin-3-yl]phenyl]methyl 3-[4-[2-(2-hydroxy-5-prop-2-ynoxycarbonylanilino)-2-oxoethoxy]phenyl]adamantane-1-carboxylateIC5010200.0 [1]
[4-[3-(Trifluoromethyl)diazirin-3-yl]phenyl]methyl 3-(4-prop-2-ynoxyphenyl)adamantane-1-carboxylateIC5020000.0 [1]
Prop-2-ynyl 4-hydroxy-3-[[2-[2-[3-(trifluoromethyl)diazirin-3-yl]phenoxy]acetyl]amino]benzoateIC5020000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-morpholin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-4-morpholin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(4-cyclopropylpiperazin-1-yl)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-[4-(oxetan-3-yl)piperazin-1-yl]phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
5-[3-(4-Acetylpiperazin-1-yl)-2,6-dichlorophenyl]-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-piperazin-1-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(oxan-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-phenylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(2-chlorophenyl)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-3-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyrimidin-5-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chloro-5-hydroxyphenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(5-Amino-2-chlorophenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-[2-Chloro-5-(methylamino)phenyl]sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetic acidIC5010000.0 [1]
2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N-methylacetamideIC5010000.0 [1]
2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N,N-dimethylacetamideIC5010000.0 [1]
2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N-(2-hydroxyethyl)acetamideIC5010000.0 [1]
Methyl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
Ethyl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
Propan-2-yl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
[(1S)-1-Phenylethyl] 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
2-(2-Chloro-5-hydroxyphenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-[4-(2,6-Dichloro-3-propan-2-yloxyphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanyl-4-hydroxybenzonitrileIC5010000.0 [1]
2-[4-(2,6-Dichloro-3-propan-2-yloxyphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanyl-4-methoxybenzonitrileIC5010000.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
Ethyl 2-[4-chloro-3-[4-(2,6-dichloro-3-phenylphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-[2,6-dichloro-3-(oxan-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
Methyl 3-[[2-(4-cyclohexylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
1-[4-[[4-(Trifluoromethyl)phenyl]methyl]piperazin-1-yl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanoneIC505400.0 [1]
Methyl 3-[4-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]butanoylamino]benzoateIC501110.0 [1]
Methyl 4-hydroxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC501890.0 [1]
Methyl 3-[[2-[4-(1-adamantyl)phenoxy]-2-methylpropanoyl]amino]benzoateIC501360.0 [1]
N-[4-(Trifluoromethyl)phenyl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamideIC501530.0 [1]
Methyl 3-[[2-(4-cyclopentylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
Methyl 4-(2-morpholin-4-ylethoxy)-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC5040000.0 [1]
N-[4-(4-Methylpiperazin-1-yl)phenyl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamideIC502900.0 [1]
N-(3-Hydroxy-1-adamantyl)-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamideIC5026900.0 [1]
Methyl 4-prop-2-ynoxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC501690.0 [1]
Methyl 3-[[2-methyl-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoyl]amino]benzoateIC501320.0 [1]
Methyl 3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC508920.0 [1]
Methyl 4-methoxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC5027470.0 [1]
1-(4-Prop-2-ynylpiperazin-1-yl)-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanoneIC5040000.0 [1]
Methyl 4-hydroxy-3-[4-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]butanoylamino]benzoateIC501110.0 [1]
Methyl 3-[[2-(4-pentylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
Methyl 3-[[2-[4-(1-adamantyl)phenoxy]acetyl]amino]-4-(2-pyrrolidin-1-ylethoxy)benzoateIC5040000.0 [1]
Methyl 4-hydroxy-3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoateIC504600.0 [1]
Methyl 3-[[2-(4-butylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
Methyl 4-hydroxy-3-[[2-methyl-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoyl]amino]benzoateIC5010980.0 [1]
Methyl 4-(2-methoxyethoxy)-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC5029020.0 [1]
Prop-2-ynyl 4-hydroxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC505880.0 [1]
Methyl 3-[[2-[4-(1-adamantyl)phenoxy]acetyl]amino]-4-(3-morpholin-4-ylpropoxy)benzoateIC5040000.0 [1]
Methyl 3-[2-(4-methylphenoxy)acetamido]benzoateIC5040000.0 [1]
Methyl 3-[[2-(4-ethylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
Methyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylateIC5013500.0 [1]
5-Benzyl-9-chloro-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC502700.0 [1]
5-Benzyl-9-tert-butyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC501600.0 [1]
5-Benzyl-9-(trifluoromethyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC504200.0 [1]
5-Benzyl-9-methyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC506200.0 [1]
9-Bromo-5-[(4-methylphenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC501600.0 [1]
9-Bromo-5-[(4-methoxyphenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC501800.0 [1]
9-Bromo-5-[(3,4-dichlorophenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC501100.0 [1]
5-[(4-Methylphenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC5010500.0 [1]
5-[(3,4-Dichlorophenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC507900.0 [1]
9-Tert-butyl-5-[(3,4-dichlorophenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-oneIC50770.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Malate dehydrogenase, mitochondrial Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/malate-dehydrogenase-mitochondrial-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Malate dehydrogenase, mitochondrial Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/malate-dehydrogenase-mitochondrial-inhibitors-ic50-ki.
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