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Malate dehydrogenase cytoplasmic Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
2',6'-Dichloro-4-((2-chlorophenyl)thio)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-oneIC5010000.0 [1], 100000.0 [2]
Methyl 3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoateIC501070.0 [1]
Methyl 3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoateKi740.0 [1]
FluconazoleIC50400000.0 [1]
GlyburideIC50400000.0 [1]
NizoralIC50150000.0 [1]
MiconazoleIC5025000.0 [1]
ClotrimazoleIC5035000.0 [1]
NicardipineIC5050000.0 [1]
Mefenamic acidIC50225000.0 [1]
EconazoleIC5025000.0 [1]
DelavirdineIC5085000.0 [1]
Benzyl benzoateIC50125000.0 [1]
OxaprozinIC50175000.0 [1]
SulconazoleIC5020000.0 [1]
CID 16124726IC501100.0 [1]
2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)acetamideIC5010000.0 [1]
2-[4-[2-[5-Hydroxy-2-[(4-methoxyphenyl)methylcarbamoyl]-4-oxochromen-7-yl]oxyethyl]-2-methoxyanilino]-2-oxoacetic acidIC506780.0 [1]
Methyl 3-[[2-(4-propylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-morpholin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-4-morpholin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(4-cyclopropylpiperazin-1-yl)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-[4-(oxetan-3-yl)piperazin-1-yl]phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
5-[3-(4-Acetylpiperazin-1-yl)-2,6-dichlorophenyl]-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-piperazin-1-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(oxan-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-phenylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(2-chlorophenyl)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-3-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyrimidin-5-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chloro-5-hydroxyphenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(5-Amino-2-chlorophenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-[2-Chloro-5-(methylamino)phenyl]sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetic acidIC5010000.0 [1]
2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N-methylacetamideIC5010000.0 [1]
2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N,N-dimethylacetamideIC5010000.0 [1]
2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N-(2-hydroxyethyl)acetamideIC5010000.0 [1]
Methyl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
Ethyl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
Propan-2-yl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
[(1S)-1-Phenylethyl] 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
2-(2-Chloro-5-hydroxyphenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
2-[4-(2,6-Dichloro-3-propan-2-yloxyphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanyl-4-hydroxybenzonitrileIC5010000.0 [1]
2-[4-(2,6-Dichloro-3-propan-2-yloxyphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanyl-4-methoxybenzonitrileIC5010000.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
Ethyl 2-[4-chloro-3-[4-(2,6-dichloro-3-phenylphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-[2,6-dichloro-3-(oxan-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
Methyl 3-[[2-(4-cyclohexylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
1-[4-[[4-(Trifluoromethyl)phenyl]methyl]piperazin-1-yl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanoneIC504740.0 [1]
Methyl 3-[4-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]butanoylamino]benzoateIC501180.0 [1]
Methyl 4-hydroxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC501140.0 [1]
Methyl 3-[[2-[4-(1-adamantyl)phenoxy]-2-methylpropanoyl]amino]benzoateIC501310.0 [1]
N-[4-(Trifluoromethyl)phenyl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamideIC503440.0 [1]
Methyl 3-[[2-(4-cyclopentylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
Methyl 4-(2-morpholin-4-ylethoxy)-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC5040000.0 [1]
N-[4-(4-Methylpiperazin-1-yl)phenyl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamideIC503000.0 [1]
N-(3-Hydroxy-1-adamantyl)-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamideIC5025960.0 [1]
Methyl 4-prop-2-ynoxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC502430.0 [1]
Methyl 3-[[2-methyl-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoyl]amino]benzoateIC501400.0 [1]
Methyl 3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC506650.0 [1]
Methyl 4-methoxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC502270.0 [1]
1-(4-Prop-2-ynylpiperazin-1-yl)-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanoneIC5040000.0 [1]
Methyl 4-hydroxy-3-[4-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]butanoylamino]benzoateIC505160.0 [1]
Methyl 3-[[2-(4-pentylphenoxy)acetyl]amino]benzoateIC506790.0 [1]
Methyl 3-[[2-[4-(1-adamantyl)phenoxy]acetyl]amino]-4-(2-pyrrolidin-1-ylethoxy)benzoateIC5040000.0 [1]
Methyl 4-hydroxy-3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoateIC501540.0 [1]
Methyl 3-[[2-(4-butylphenoxy)acetyl]amino]benzoateIC509580.0 [1]
Methyl 4-hydroxy-3-[[2-methyl-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoyl]amino]benzoateIC503000.0 [1]
Methyl 4-(2-methoxyethoxy)-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC5018350.0 [1]
Prop-2-ynyl 4-hydroxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoateIC50920.0 [1]
Methyl 3-[[2-[4-(1-adamantyl)phenoxy]acetyl]amino]-4-(3-morpholin-4-ylpropoxy)benzoateIC5040000.0 [1]
Methyl 3-[2-(4-methylphenoxy)acetamido]benzoateIC5040000.0 [1]
Methyl 3-[[2-(4-ethylphenoxy)acetyl]amino]benzoateIC5040000.0 [1]
Methyl 3-[[2-[4-(trifluoromethyl)phenoxy]acetyl]amino]benzoateIC5040000.0 [1]
Methyl 3-{[(4-nitrophenoxy)acetyl]amino}benzoateIC5040000.0 [1]
[(1R)-1-Phenylethyl] 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC5010000.0 [1]
Items per page: 1 - 10 of 80
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References

This online tool may be cited as follows

MLA

"Quest Database™ Malate dehydrogenase cytoplasmic Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/malate-dehydrogenase-cytoplasmic-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Malate dehydrogenase cytoplasmic Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/malate-dehydrogenase-cytoplasmic-inhibitors-ic50-ki.
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