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Macrophage migration inhibitory factor Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl esterIC5025000.0 [1]
6-[alpha-Morpholino-4-(trifluoromethyl)benzyl]-1,3-benzodioxole-5-olIC50360.0 [1], 570.0 [2], 2400.0 [3], 6120.0 [4]
6-[alpha-Morpholino-4-(trifluoromethyl)benzyl]-1,3-benzodioxole-5-olKi52.0 [1], 570.0 [2]
3',4',7-TrihydroxyisoflavoneIC5038.0 [1]
3',4',7-TrihydroxyisoflavoneKi38.0 [1], 15000.0 [2]
3-Acetyl-7-hydroxy-2H-chromen-2-oneIC5045200.0 [1], 103200.0 [2]
3-Acetyl-7-hydroxy-2H-chromen-2-oneKi4300.0 [1]
Benzyl isothiocyanateIC50530.0 [1], 540.0 [2], 790.0 [3]
6-[2-(2-Morpholinoethoxy)ethoxy]-2-[1-(4-hydroxyphenyl)-1H-1,2,3-triazole-4-yl]quinolineKi160.0 [1], 161.0 [2], 410.0 [3]
(S)-Methyl 2-(4-hydroxybenzylideneamino)-3-(1H-indol-3-yl)propanoateIC501600.0 [1], 1650.0 [2]
Methyl (5R)-3-(4-hydroxyphenyl)-4,5-dihydro-1,2-oxazole-5-carboxylateKi24000.0 [1], 27300.0 [2], 30100.0 [3]
4-{4-[6-(2-Methoxyethoxy)quinolin-2-Yl]-1h-1,2,3-Triazol-1-Yl}phenolKi200.0 [1], 550.0 [2], 650.0 [3]
4-Hydroxybenzaldehyde O-(Cyclohexylcarbonyl)oximeIC501300.0 [1], 1570.0 [2]
2-[2-[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]ethyl]isoindole-1,3-dioneIC50500.0 [1], 800.0 [2], 1500.0 [3]
1-[2-[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]ethyl]pyrrolidine-2,5-dioneIC5015000.0 [1], 20000.0 [2], 50000.0 [3]
2-Fluoro-4-[5-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]methyl]-4,5-dihydro-1,2-oxazol-3-yl]phenolIC5015000.0 [1], 48000.0 [2], 60000.0 [3]
2,2,2-Trifluoro-N-[2-[3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]ethyl]acetamideIC5015000.0 [1], 49000.0 [2], 100000.0 [3]
N-[2-[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]ethyl]-2,2-dimethylpropanamideIC5015000.0 [1], 22000.0 [2], 28000.0 [3]
4-Fluoro-N-[2-[3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]ethyl]benzamideIC5010000.0 [1], 15000.0 [2], 20000.0 [3]
N-[2-[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]ethyl]-3-methylbutanamideIC5020000.0 [1], 22000.0 [2], 29000.0 [3]
3-Fluorobenzyl isothiocyanateIC501500.0 [1], 11000.0 [2], 54000.0 [3]
3-[3-[3-(3-Fluoro-4-methoxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazol-5-yl]propanoic acidIC5012000.0 [1], 60000.0 [2], 100000.0 [3]
5-Amino-3-dodecyl-1H-chromeno[3,4-c]pyridine-2,4(3H,10bH)-dioneIC5013500.0 [1], 13800.0 [2], 18000.0 [3]
4-Fluorobenzyl isothiocyanateIC50540.0 [1], 9600.0 [2], 31000.0 [3]
SulforaphaneIC502200.0 [1], 11000.0 [2]
HexachloropheneIC506000.0 [1]
HexachloropheneKi5550.0 [1]
Phenethyl isothiocyanateIC501600.0 [1], 16000.0 [2]
Allyl isothiocyanateIC50250.0 [1], 1100.0 [2]
EbselenIC502400.0 [1]
EbselenKi570.0 [1]
EpoxyazadiradioneIC506000.0 [1], 6400.0 [2]
Ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylateKi7400.0 [1]
7-Hydroxy-3-phenyl-2H-chromen-2-oneKi470.0 [1]
3-Benzyl-5-methyl-3H-benzooxazol-2-oneIC50500.0 [1]
Butyl 1,3-benzoxazol-2-ylsulfanylformateIC5080.0 [1], 150.0 [2]
4-Methoxybenzyl isothiocyanateIC50700.0 [1], 3900.0 [2]
3-({[(4-Biphenylylcarbonyl)amino]carbonothioyl}amino)benzoic acidKi348.0 [1], 4270.0 [2]
4-(2-Isothiocyanatoethyl)phenolIC501200.0 [1], 3600.0 [2]
3-({2-[1-(3-Fluoro-4-Hydroxyphenyl)-1h-1,2,3-Triazol-4-Yl]quinolin-5-Yl}oxy)benzoic AcidKi14.0 [1], 57.0 [2]
1-(2-Chlorophenyl)-3-pyridin-2-ylthioureaIC501010.0 [1], 1040.0 [2]
2-(4-Chlorophenyl)-6-fluoro-1,2-benzothiazol-3-oneIC504200.0 [1]
6-Phenylpyridazin-3-yl thiophene-2-carboxylateIC5050.0 [1]
3,4-Dihydroxyphenethyl isothiocyanateIC504000.0 [1], 29000.0 [2]
4-(Isothiocyanatomethyl)benzene-1-sulfonamideIC50500.0 [1], 750.0 [2]
2-Fluoro-4-[4-[6-[2-(2-morpholin-4-ylethoxy)ethoxy]quinolin-2-yl]triazol-1-yl]phenolKi74.0 [1]
2-[2-[1-(3-Fluoro-4-hydroxyphenyl)triazol-4-yl]quinolin-6-yl]oxyacetic acidKi48.0 [1]
4-[2-[1-(3-Fluoro-4-hydroxyphenyl)triazol-4-yl]quinolin-6-yl]oxybutanoic acidKi39.0 [1]
2-[2-[1-(4-Hydroxyphenyl)triazol-4-yl]quinolin-6-yl]oxyacetic acidKi200.0 [1]
3-{[(1-Benzofuran-2-ylcarbonyl)carbamothioyl]amino}-4-methoxybenzoic acidKi5141.0 [1], 26790.0 [2]
4-[4-[6-(2-Hydroxyethoxy)quinolin-2-yl]triazol-1-yl]phenolKi530.0 [1]
4-[4-[6-[2-(2-Aminoethoxy)ethoxy]quinolin-2-yl]triazol-1-yl]phenol;2,2,2-trifluoroacetic acidKi360.0 [1]
4-[4-[6-[2-(2-Aminoethoxy)ethoxy]quinolin-2-yl]triazol-1-yl]-2-fluorophenol;2,2,2-trifluoroacetic acidKi144.0 [1]
Neopentyl 2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetateIC50750.0 [1], 1070.0 [2]
7-Hydroxy-3-pyrazolo[1,5-a]pyridin-2-yl-chromen-2-oneKi500.0 [1]
2-[4-(1,3-Benzothiazol-2-yl)-2-bromo-6-methoxyphenoxy]acetic acidKi4521.0 [1], 10900.0 [2]
2-(4-Chlorophenyl)-6-hydroxy-1,2-benzothiazol-3-oneIC501000.0 [1]
2-(4-Chlorophenyl)-6-hydroxy-1,2-benzothiazol-3-oneKi10000.0 [1]
7-Hydroxy-3-(2-methyl-thiazol-4-yl)-chromen-2-oneKi2100.0 [1]
2-(4-Chlorophenyl)-6-methoxy-1,2-benzothiazol-3-oneIC501900.0 [1]
2-(4-Chlorophenyl)-6-methoxy-1,2-benzothiazol-3-oneKi5370.0 [1]
Ethyl 2-cyano-3-(2,4-dihydroxyphenyl)acrylateIC5062100.0 [1], 110200.0 [2]
1-Phenyl-3-(1,3,4-thiadiazol-2-yl)thioureaIC50300.0 [1], 420.0 [2]
1-(2-Methoxybenzoyl)-1H-1,2,3-benzotriazoleIC506900.0 [1], 12200.0 [2]
4-[4-(Quinolin-2-Yl)-1h-1,2,3-Triazol-1-Yl]phenolKi230.0 [1]
4-Imidazo[1,2-a]pyridin-3-ylbenzene-1,2-diolIC50110.0 [1]
4-Imidazo[1,2-a]pyridin-3-ylbenzene-1,2-diolKi45200.0 [1]
N-(2-Bromobenzoyloxy)-4-chlorobenzamideIC502800.0 [1], 4200.0 [2]
2-Fluoro-4-[5-(5-methyl-1,2,4-oxadiazol-3-yl)-4,5-dihydro-1,2-oxazol-3-yl]phenolIC5060000.0 [1], 100000.0 [2]
2-[[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl]isoindole-1,3-dioneIC5029000.0 [1], 36000.0 [2]
2-Fluoro-4-[5-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-4,5-dihydro-1,2-oxazol-3-yl]phenolIC5060000.0 [1], 100000.0 [2]
2-[3-[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]propyl]isoindole-1,3-dioneIC502000.0 [1], 7000.0 [2]
N-Cyclohexyl-3-[3-[3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazol-5-yl]propanamideIC5025000.0 [1], 100000.0 [2]
Methyl 3-[3-[3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazol-5-yl]propanoateIC5050000.0 [1], 100000.0 [2]
3-[3-[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazol-5-yl]benzene-1,2-diolIC5019000.0 [1], 100000.0 [2]
Methyl (5S)-3-(4-hydroxyphenyl)-4,5-dihydro-1,2-oxazole-5-carboxylateIC507000.0 [1], 11300.0 [2]
[(E)-(3-Fluoro-4-hydroxyphenyl)methylideneamino] pyridine-3-carboxylateIC50410.0 [1]
[(E)-(3-Fluoro-4-hydroxyphenyl)methylideneamino] pyridine-3-carboxylateKi3300.0 [1]
1-Chloro-4-(2-isothiocyanatoethyl)benzeneIC501100.0 [1], 1600.0 [2]
N-[(2-Chlorophenyl)carbamothioyl]-4-nitrothiophene-2-carboxamideIC507080.0 [1]
N-[(2-Chlorophenyl)carbamothioyl]-4-nitrothiophene-2-carboxamideKi2470.0 [1]
(1-Isothiocyanatoethyl)benzeneIC501000.0 [1], 2800.0 [2]
5-(Isothiocyanatomethyl)-1,3-benzodioxoleIC502900.0 [1], 5000.0 [2]
3-[[3-(3-Fluoro-4-methoxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl]-5-(trifluoromethyl)-1,2,4-oxadiazoleIC5055000.0 [1], 100000.0 [2]
5-(2,3-Dimethoxyphenyl)-3-[3-(3-fluoro-4-methoxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazoleIC5020000.0 [1], 32000.0 [2]
3-[3-(3-Fluoro-4-methoxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-5-(trifluoromethyl)-1,2,4-oxadiazoleIC5095000.0 [1], 100000.0 [2]
N-Cyclohexyl-3-[3-[3-(3-fluoro-4-methoxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazol-5-yl]propanamideIC509500.0 [1], 30000.0 [2]
4-(1-Isothiocyanatopropan-2-yl)phenolIC504800.0 [1], 28000.0 [2]
Methyl 2-(4-methyl-5-(2-thienyl)-1,2,4-triazol-3-ylthio)acetateIC5018600.0 [1], 28400.0 [2]
1-(2-Isothiocyanatoethyl)-4-(trifluoromethyl)benzeneIC507100.0 [1], 40000.0 [2]
3-(2-Isothiocyanatoethyl)phenolIC507800.0 [1], 62000.0 [2]
4-[4-[6-(2-Aminoethoxy)quinolin-2-yl]triazol-1-yl]phenolKi260.0 [1]
SodiumIC50810.0 [1]
DL-ThyroxineIC5015800.0 [1]
Ellagic acidKi1950.0 [1]
Phenyl isothiocyanateIC5011000.0 [1]
AcetimidoquinoneIC5040000.0 [1]
s-HexylglutathioneIC503300000.0 [1]
6-Phenylhexyl isothiocyanateIC504200.0 [1]
1-HexanethiolIC5017400000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Macrophage migration inhibitory factor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/macrophage-migration-inhibitory-factor-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Macrophage migration inhibitory factor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/macrophage-migration-inhibitory-factor-inhibitors-ic50-ki.
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