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Lysyl oxidase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
3-AminopropanenitrileIC50550.0 [1], 100000.0 [2]
DisulfiramIC50320.0 [1]
ThiramIC501040.0 [1]
PyrithioneIC5033000.0 [1]
4-Pyridinemethanamine, 3,5-diethoxy-IC501000000.0 [1]
4,6-Dimethyl-2-phenyl-2H-pyrazolo[3,4-b]pyridin-3-olIC5035000.0 [1]
6-Methyl-3-[(2E)-2-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylidene]hydrazinyl]-4H-1,2,4-triazin-5-oneIC501600.0 [1]
3,4-Dimethyl-1-phenyl-1H-pyrazol-5(4H)-oneIC502600.0 [1]
2-(4,6-Difluoroindan-1-ylidene)-acetamide, (E)-IC5030000.0 [1]
2-Mercapto-3-phenylpyrido[2,3-d]pyrimidin-4(3H)-oneIC50100000.0 [1]
(2-Methoxypyridin-4-yl)methanamineIC5016000.0 [1]
(2-Chloropyridin-4-yl)methanamineIC505910.0 [1]
(2-Phenoxypyridin-4-yl)methanamine hydrochlorideIC508700.0 [1]
[3-[4-(Aminomethyl)pyridin-2-yl]oxyphenyl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanoneIC502800.0 [1]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(2-methoxyethyl)benzamide;hydrochlorideIC507300.0 [1]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(1-benzothiophen-2-ylmethyl)benzamide;hydrochlorideIC502900.0 [1]
4-[4-(Aminomethyl)pyridin-2-yl]oxy-N-phenylbenzamide;hydrochlorideIC505500.0 [1]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-phenylbenzamide;hydrochlorideIC503100.0 [1]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(4-fluorophenyl)benzamide;hydrochlorideIC501800.0 [1]
4-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(2-methoxyethyl)benzamide;hydrochlorideIC508400.0 [1]
[2-(3-Phenoxyphenoxy)-6-(trifluoromethyl)pyridin-4-yl]methanamineIC5093000.0 [1]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylbenzamide;hydrochlorideIC5011000.0 [1]
(3R)-3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylpiperidine-1-carboxamideIC50100000.0 [1]
(3S)-3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylpiperidine-1-carboxamideIC5018000.0 [1]
[3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-[(3R)-3-hydroxypyrrolidin-1-yl]methanone;hydrochlorideIC5030000.0 [1]
PAT-1251 HydrochlorideIC5035000.0 [1]
[3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-[(3R)-3-aminopyrrolidin-1-yl]methanone;dihydrochlorideIC5021000.0 [1]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-(2-sulfamoylethyl)benzamide;hydrochlorideIC5023000.0 [1]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-[(2R)-2,3-dihydroxypropyl]benzamide;hydrochlorideIC5022000.0 [1]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-[2-(tetrazol-1-yl)ethyl]benzamide;hydrochlorideIC5016000.0 [1]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-(1-benzothiophen-2-ylmethyl)benzamide;hydrochlorideIC5011000.0 [1]
4-[[3-[4-(Aminomethyl)pyridin-2-yl]oxybenzoyl]amino]benzoic acid;hydrochlorideIC5016000.0 [1]
(4Z)-4-(1-Ethylquinolin-2(1H)-ylidene)-2-phenyl-5-(phenylamino)-2,4-dihydro-3H-pyrazol-3-oneIC509200.0 [1]
[3-[4-(Aminomethyl)pyridin-2-yl]oxyphenyl]-[(3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanone;hydrochlorideIC5045000.0 [1]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-[(4-carbamimidoylphenyl)methyl]benzamide;dihydrochlorideIC503500.0 [1]
[2-(Cyclohexyloxy)pyridin-4-yl]methanamineIC5034000.0 [1]
Diethyl 5-[(5-amino-3-oxo-2-phenyl-1H-pyrazol-4-yl)diazenyl]-3-methylthiophene-2,4-dicarboxylateIC505000.0 [1]
3-Tert-Butyl-1-phenyl-2-pyrazolin-5-oneIC5075000.0 [1]
2-Phenyl-6-(2-thienyl)-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-oneIC50100000.0 [1]
6-(2,5-Dimethyl-3-furyl)-2-phenyl-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-oneIC5050000.0 [1]
4-[4-(Aminomethyl)-5-(4-hydroxybutoxy)pyridin-3-yl]oxybutan-1-ol;dihydrochlorideIC50100000.0 [1]
2-[4-(Aminomethyl)-5-(2-hydroxyethoxy)pyridin-3-yl]oxyethanol;trihydrate;dihydrochlorideIC50100000.0 [1]
(3-Ethoxy-5-phenylmethoxypyridin-4-yl)methanamine;dihydrochlorideIC501000000.0 [1]
6-(2-Methoxyphenyl)-2-phenyl-1H-pyrazolo[3,4-b]pyridine-3,4(2H,7H)-dioneIC5091000.0 [1]
(2-(Trifluoromethyl)pyridin-4-yl)methanamine hydrochlorideIC5054000.0 [1]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-benzylbenzamideIC503100.0 [1]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(4-methoxyphenyl)benzamideIC502400.0 [1]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-methoxybenzamideIC5083000.0 [1]
[3-[4-(Aminomethyl)pyridin-2-yl]oxyphenyl]-[(3S,4S)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanoneIC5052000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Lysyl oxidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/lysyl-oxidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ Lysyl oxidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysyl-oxidase-inhibitors-ic50-ki.
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