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Lysyl oxidase homolog 2 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
3-AminopropanenitrileIC5083.0 [1]
(2-Methoxypyridin-4-yl)methanamineIC501180.0 [1], 1200.0 [2], 1400.0 [3], 35000.0 [4]
(2-Chloropyridin-4-yl)methanamineIC50126.0 [1], 190.0 [2], 1450.0 [3]
(2-Phenoxypyridin-4-yl)methanamine hydrochlorideIC50310.0 [1], 860.0 [2], 6700.0 [3]
[3-[4-(Aminomethyl)pyridin-2-yl]oxyphenyl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanoneIC50120.0 [1], 370.0 [2], 7900.0 [3]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(2-methoxyethyl)benzamide;hydrochlorideIC50160.0 [1], 290.0 [2], 2900.0 [3]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(1-benzothiophen-2-ylmethyl)benzamide;hydrochlorideIC5079.0 [1], 110.0 [2], 1700.0 [3]
4-[4-(Aminomethyl)pyridin-2-yl]oxy-N-phenylbenzamide;hydrochlorideIC50270.0 [1], 750.0 [2], 39000.0 [3]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-phenylbenzamide;hydrochlorideIC5056.0 [1], 130.0 [2], 1300.0 [3]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(4-fluorophenyl)benzamide;hydrochlorideIC5050.0 [1], 130.0 [2], 1600.0 [3]
4-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(2-methoxyethyl)benzamide;hydrochlorideIC50500.0 [1], 1500.0 [2], 30000.0 [3]
[2-(3-Phenoxyphenoxy)-6-(trifluoromethyl)pyridin-4-yl]methanamineIC5067.0 [1], 270.0 [2], 23000.0 [3]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylbenzamide;hydrochlorideIC5042.0 [1], 62.0 [2], 2900.0 [3]
(3R)-3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylpiperidine-1-carboxamideIC50570.0 [1], 620.0 [2], 40000.0 [3]
(3S)-3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylpiperidine-1-carboxamideIC50130.0 [1], 160.0 [2], 2000.0 [3]
[3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-[(3R)-3-hydroxypyrrolidin-1-yl]methanone;hydrochlorideIC50110.0 [1], 150.0 [2], 910.0 [3]
[3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-[(3R)-3-aminopyrrolidin-1-yl]methanone;dihydrochlorideIC5058.0 [1], 100.0 [2], 690.0 [3]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-(2-sulfamoylethyl)benzamide;hydrochlorideIC5035.0 [1], 62.0 [2], 310.0 [3]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-[(2R)-2,3-dihydroxypropyl]benzamide;hydrochlorideIC5077.0 [1], 88.0 [2], 550.0 [3]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-[2-(tetrazol-1-yl)ethyl]benzamide;hydrochlorideIC5043.0 [1], 80.0 [2], 280.0 [3]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-(1-benzothiophen-2-ylmethyl)benzamide;hydrochlorideIC5034.0 [1], 100.0 [2], 9900.0 [3]
4-[[3-[4-(Aminomethyl)pyridin-2-yl]oxybenzoyl]amino]benzoic acid;hydrochlorideIC5081.0 [1], 300.0 [2], 1400.0 [3]
[3-[4-(Aminomethyl)pyridin-2-yl]oxyphenyl]-[(3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanone;hydrochlorideIC5074.0 [1], 110.0 [2], 710.0 [3]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-[(4-carbamimidoylphenyl)methyl]benzamide;dihydrochlorideIC50180.0 [1], 650.0 [2], 5200.0 [3]
[2-(Cyclohexyloxy)pyridin-4-yl]methanamineIC50850.0 [1], 1800.0 [2], 29000.0 [3]
(2-(Trifluoromethyl)pyridin-4-yl)methanamine hydrochlorideIC501000.0 [1], 1400.0 [2], 7900.0 [3]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-benzylbenzamideIC5062.0 [1], 110.0 [2], 1400.0 [3]
3-[4-(Aminomethyl)pyridin-2-yl]oxy-N-(4-methoxyphenyl)benzamideIC5053.0 [1], 160.0 [2], 1800.0 [3]
3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-methoxybenzamideIC5096.0 [1], 140.0 [2], 840.0 [3]
[3-[4-(Aminomethyl)pyridin-2-yl]oxyphenyl]-[(3S,4S)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanoneIC5082.0 [1], 120.0 [2], 1150.0 [3]
PAT-1251 HydrochlorideIC5078.0 [1], 100.0 [2]
DisulfiramIC50150.0 [1]
PhenethylamineIC5060100.0 [1]
BenzylamineIC5064700.0 [1]
ThiramIC50170.0 [1]
PyrithioneIC5018000.0 [1]
(1S,2R)-2-Phenylcyclopropan-1-amine;(1R,2S)-2-phenylcyclopropan-1-amineIC50100000.0 [1]
4-PyridinemethanamineIC501220.0 [1]
4-FluorobenzylamineIC5026000.0 [1]
4-NitrobenzylamineIC50719.0 [1]
4-(Aminomethyl)benzenecarboximidamideIC501110.0 [1]
4,6-Dimethyl-2-phenyl-2H-pyrazolo[3,4-b]pyridin-3-olIC5025000.0 [1]
4-AminobenzylamineIC5047000.0 [1]
Methyl 4-(aminomethyl)benzoateIC503620.0 [1]
4-(Aminomethyl)benzonitrileIC50670.0 [1]
4-(2-Aminoethyl)pyridineIC508210.0 [1]
6-Methyl-3-[(2E)-2-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylidene]hydrazinyl]-4H-1,2,4-triazin-5-oneIC5034000.0 [1]
3,4-Dimethyl-1-phenyl-1H-pyrazol-5(4H)-oneIC502100.0 [1]
2-Mercapto-3-phenylpyrido[2,3-d]pyrimidin-4(3H)-oneIC5075000.0 [1]
Methyl 3-(aminomethyl)benzoateIC503540.0 [1]
4-(Methylaminomethyl)benzonitrileIC5035000.0 [1]
Quinolin-4-ylmethanamineIC506040.0 [1]
(4Z)-4-(1-Ethylquinolin-2(1H)-ylidene)-2-phenyl-5-(phenylamino)-2,4-dihydro-3H-pyrazol-3-oneIC501000.0 [1]
[2-Pyridin-3-yl-5-(trifluoromethyl)pyridin-4-yl]methanamineIC5031000.0 [1]
[2-(1H-Imidazol-1-yl)pyridin-4-yl]methanamineIC50203.0 [1]
(2-Phenoxypyridin-4-yl)methylamineIC50309.0 [1]
[4-(1,3-Thiazol-2-yl)phenyl]methylamineIC50902.0 [1]
Diethyl 5-[(5-amino-3-oxo-2-phenyl-1H-pyrazol-4-yl)diazenyl]-3-methylthiophene-2,4-dicarboxylateIC50100000.0 [1]
4-MethylaminobenzylamineIC50100000.0 [1]
(2-Fluoropyridin-4-yl)methanamineIC50385.0 [1]
3-Tert-Butyl-1-phenyl-2-pyrazolin-5-oneIC50100000.0 [1]
3-(Aminomethyl)benzimidamideIC504970.0 [1]
2-Phenyl-6-(2-thienyl)-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-oneIC507800.0 [1]
6-(2,5-Dimethyl-3-furyl)-2-phenyl-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-oneIC503800.0 [1]
(3-Fluoropyridin-4-yl)methanamineIC50431.0 [1]
(2-(Trifluoromethyl)pyridin-4-yl)methanamineIC50999.0 [1]
6-(2-Methoxyphenyl)-2-phenyl-1H-pyrazolo[3,4-b]pyridine-3,4(2H,7H)-dioneIC5045000.0 [1]
(2-Pyridin-3-ylpyridin-4-yl)methanamineIC50321.0 [1]
Items per page: 1 - 10 of 68
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lysyl oxidase homolog 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/lysyl-oxidase-homolog-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Lysyl oxidase homolog 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysyl-oxidase-homolog-2-inhibitors-ic50-ki.
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