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Lysosomal alpha-mannosidase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
SwainsonineIC5010.0 [1], 50.0 [2], 20000.0 [3]
(2R,3R,4S)-2-({[(1R)-2-Hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diolIC5050000.0 [1]
(2R,3R,4S)-2-({[(1R)-2-Hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diolKi23300.0 [1]
[(2R)-2-[[(2R,3R,4S)-3,4-Dihydroxypyrrolidin-2-yl]methylamino]-2-phenylethyl] 4-bromobenzoateIC5075000.0 [1], 200000.0 [2]
(3r,4r,5r)-3,4-Dihydroxy-5-({[(1r)-2-Hydroxy-1-Phenylethyl]amino}methyl)pyrrolidin-2-OneIC5050000.0 [1], 75000.0 [2], 350000.0 [3]
(3r,4r,5r)-3,4-Dihydroxy-5-({[(1r)-2-Hydroxy-1-Phenylethyl]amino}methyl)-1-Methylpyrrolidin-2-OneKi550.0 [1], 670.0 [2], 3200.0 [3]
[(2R)-2-[[(2R,3R,4R)-3,4-Dihydroxy-1-methyl-5-oxopyrrolidin-2-yl]methylamino]-2-phenylethyl] 4-bromobenzoateIC50750.0 [1], 7500.0 [2], 75000.0 [3]
[(2R)-2-[[(2R,3R,4R)-3,4-Dihydroxy-5-oxopyrrolidin-2-yl]methylamino]-2-phenylethyl] 4-bromobenzoateIC5075000.0 [1], 150000.0 [2], 750000.0 [3]
MiglitolIC50379000.0 [1]
(3S,5R)-4-(2-Hydroxyethyl)piperidine-3,4,5-triolIC501826000.0 [1]
(3S,5R)-1-Butyl-4-(2-hydroxyethyl)piperidine-3,4,5-triolIC50252000.0 [1]
(3R,5S)-1-Hexyl-4-(2-hydroxyethyl)piperidine-3,4,5-triolIC50183000.0 [1]
(3R,5S)-4-(2-Hydroxyethyl)-1-octylpiperidine-3,4,5-triolIC50143000.0 [1]
(3S,5R)-1-Decyl-4-(2-hydroxyethyl)piperidine-3,4,5-triolIC50112000.0 [1]
(3S,5R)-1,4-Bis(2-hydroxyethyl)piperidine-3,4,5-triolIC50873000.0 [1]
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3S,4R,5R)-IC5064000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Lysosomal alpha-mannosidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/lysosomal-alpha-mannosidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Lysosomal alpha-mannosidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysosomal-alpha-mannosidase-inhibitors-ic50-ki.
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