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Lysophosphatidic acid receptor Edg-7 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-2-ylmethoxy)phenyl]propyl] dihydrogen phosphateIC50175.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-2-ylmethoxy)phenyl]propyl] dihydrogen phosphateKi175.0 [1]
CID 10367662IC50301.0 [1]
CID 10367662Ki148.0 [1]
Dodecyl dihydrogen phosphateIC50384.0 [1]
Dodecyl dihydrogen phosphateKi121.0 [1]
Tetradecylphosphonic acidIC503100.0 [1]
Tetradecylphosphonic acidKi1120.0 [1]
Dioctanoylglycerol pyrophosphateIC50454.0 [1]
Dioctanoylglycerol pyrophosphateKi202.0 [1]
Decyl dihydrogen phosphateIC50384.0 [1]
Decyl dihydrogen phosphateKi121.0 [1]
Decylphosphonic acidIC501200.0 [1]
Decylphosphonic acidKi680.0 [1]
Dodecylphosphonic acidIC50654.0 [1]
Dodecylphosphonic acidKi303.0 [1]
2-(1,3-Dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic acidIC502992.0 [1]
2-(1,3-Dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic acidKi1084.0 [1]
Tetradecyl dihydrogen phosphateIC50422.0 [1]
Tetradecyl dihydrogen phosphateKi211.0 [1]
Dodecyl-thiophosphateIC5028.0 [1]
Dodecyl-thiophosphateKi14.0 [1]
3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acidIC501230.0 [1]
3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acidKi310.0 [1]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-2-ylmethoxy)phenyl]propyl] dihydrogen phosphateIC50940.0 [1]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-2-ylmethoxy)phenyl]propyl] dihydrogen phosphateKi940.0 [1]
Phosphoric acid mono-((E)-tetradec-9-enyl) esterIC5096.0 [1]
Phosphoric acid mono-((E)-tetradec-9-enyl) esterKi58.0 [1]
Thiophosphoric acid (E)-dodec-9-enyl esterIC5027.0 [1]
Thiophosphoric acid (E)-dodec-9-enyl esterKi14.0 [1]
Phosphoric acid mono-((E)-dodec-9-enyl) esterIC5032.0 [1]
Phosphoric acid mono-((E)-dodec-9-enyl) esterKi27.0 [1]
Dihydroxy-sulfanylidene-[(E)-tetradec-9-enoxy]-lambda5-phosphaneIC5028.0 [1]
Dihydroxy-sulfanylidene-[(E)-tetradec-9-enoxy]-lambda5-phosphaneKi14.0 [1]
Thiophosphoric acid decyl esterIC50122.0 [1]
Thiophosphoric acid decyl esterKi49.0 [1]
Phosphoric acid mono-((E)-dec-4-enyl) esterIC50830.0 [1]
Phosphoric acid mono-((E)-dec-4-enyl) esterKi370.0 [1]
Thiophosphoric acid dec-9-enyl esterIC50340.0 [1]
Thiophosphoric acid dec-9-enyl esterKi128.0 [1]
Phosphoric acid mono-((E)-tetradec-11-enyl) esterIC50103.0 [1]
Phosphoric acid mono-((E)-tetradec-11-enyl) esterKi40.0 [1]
Thiophosphoric acid tetradecyl esterIC50162.0 [1]
Thiophosphoric acid tetradecyl esterKi76.0 [1]
(1,1-Difluoro-pentadecyl)-phosphonic acidIC501513.0 [1]
(1,1-Difluoro-pentadecyl)-phosphonic acidKi575.0 [1]
Phosphoric acid monodec-9-enyl esterIC50770.0 [1]
Phosphoric acid monodec-9-enyl esterKi504.0 [1]
2-Hexadecanoylamino-3-(4-phosphonooxy-phenyl)-propionic acidIC505570.0 [1]
2-Hexadecanoylamino-3-(4-phosphonooxy-phenyl)-propionic acidKi2325.0 [1]
2-(3-(4-Nitrophenoxy)phenyl)-1,3-dioxoisoindoline-5-carboxylic acidIC50752.0 [1]
2-(3-(4-Nitrophenoxy)phenyl)-1,3-dioxoisoindoline-5-carboxylic acidKi230.0 [1]
[(2S)-2-(Octadecanoylamino)-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateIC501186.0 [1]
[(2S)-2-(Octadecanoylamino)-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateKi588.0 [1]
1-[4-[4-[1-Methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC502290.0 [1]
[(1R)-1-Phenylethyl] N-[3-methyl-5-[4-[4-[1-(methylsulfonylcarbamoyl)cyclopropyl]phenyl]phenyl]triazol-4-yl]carbamateIC502310.0 [1]
2-[4-[4-[1-Methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]acetic acidIC5021940.0 [1]
1-[4-[3-Fluoro-4-[1-methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC5027350.0 [1]
1-[4-[4-[1-Methyl-5-[[(1S)-1-[3-(trifluoromethyl)phenyl]ethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC506300.0 [1], 6310.0 [2]
1-[4-[4-[1-Methyl-5-[[(1R)-1-[3-(trifluoromethyl)phenyl]ethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC50132.0 [1]
[(1R)-1-[3-(Trifluoromethyl)phenyl]ethyl] N-[3-methyl-5-[4-[4-[1-(methylsulfonylcarbamoyl)cyclopropyl]phenyl]phenyl]triazol-4-yl]carbamateIC5065.0 [1], 65.7 [2]
2-[4-[4-[1-Methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-4-yl]phenyl]cyclohexyl]acetic acidIC5018600.0 [1], 18640.0 [2]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateIC506450.0 [1], 10000.0 [2]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-3-ylmethoxy)phenyl]propyl] dihydrogen phosphateKi1688.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateIC5010000.0 [1]
(4'-(4-((R)-1-(2-Chlorophenyl)ethoxycarbonylamino)-3-methylisoxazol-5-yl)biphenyl-4-yl)acetic acidIC501600.0 [1]
4-(3-Benzamidophenylamino)-4-oxobut-2-enoic acidKi316.6 [1]
LPA2 antagonist 1IC5050000.0 [1]
AM095 free acidIC508000.0 [1]
CID 66775043IC5010000.0 [1]
[1-Bromo-(3S)-hydrox-4-(palmitoyloxy)butyl]phosphateKi170.0 [1]
2-((3-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoic acidIC506600.0 [1]
2-[4-[[(3,5-Dimethoxybenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]benzoic acidIC5040.0 [1]
E,E-3-[4'-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarbamoyl]-acrylic acidKi7020.0 [1]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-prop-2-ynoxyphenyl)propyl] dihydrogen phosphateIC5010000.0 [1]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-prop-2-enoxyphenyl)propyl] dihydrogen phosphateIC5010000.0 [1]
[(2S)-3-[4-[(3-Methoxyphenyl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC50642.0 [1]
(2-Hydroxy-2-sulfanylidene-1,2lambda5-oxaphospholan-5-yl)methyl hexadecanoateIC502340.0 [1]
(2-Hydroxy-2-sulfanylidene-1,2lambda5-oxaphospholan-5-yl)methyl octadecanoateKi636.0 [1]
(2r)-3-(Phosphonooxy)propane-1,2-Diyl DiheptanoateIC50143.0 [1]
[2-(Octanoylamino)-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateIC5010000.0 [1]
[3-(4-Phenylmethoxyphenyl)-2-(tetradecanoylamino)propyl] dihydrogen phosphateIC5010000.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propyl] dihydrogen phosphateIC5010000.0 [1]
[2-[[(9Z,12Z)-Octadeca-9,12-dienoyl]amino]-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateIC5010000.0 [1]
[(2R)-3-(4-Methoxyphenyl)-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC5010000.0 [1]
[(2S)-3-(4-Ethoxyphenyl)-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC506930.0 [1]
[(2S)-3-[4-(3-Methylbutoxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC505920.0 [1]
[(2R)-3-[4-(3-Methylbutoxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC50351.0 [1]
[(2R)-3-(4-Hex-5-ynoxyphenyl)-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC503280.0 [1]
[(2R)-3-(4-Ethoxyphenyl)-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC506410.0 [1]
[(2R)-3-[4-(Cyclohexylmethoxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC504030.0 [1]
[(2R)-3-[4-[(3-Methoxyphenyl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC5035.6 [1]
[4-[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-phosphonooxypropyl]phenyl] 3,4,5-trimethoxybenzoateIC50427.0 [1]
[(2R)-3-[4-(2,3-Dihydro-1H-inden-2-yloxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC502310.0 [1]
[4-[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-phosphonooxypropyl]phenyl] 4-pentylbenzoateIC5010000.0 [1]
4-Amino-benzoic acid 4-[(S)-2-((Z)-octadec-9-enoylamino)-3-phosphonooxy-propyl]-phenyl esterIC5010000.0 [1]
[2-(Hexadecanoylamino)-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateIC506840.0 [1]
[2-(Hexadecanoylamino)-3-[4-[(3-methoxyphenyl)methoxy]phenyl]propyl] dihydrogen phosphateIC507220.0 [1]
[(2S)-3-[4-(1H-Indol-2-yloxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC509260.0 [1]
[(2R)-3-[4-(1H-Indol-2-yloxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC502630.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Lysophosphatidic acid receptor Edg-7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/lysophosphatidic-acid-receptor-edg-7-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Lysophosphatidic acid receptor Edg-7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysophosphatidic-acid-receptor-edg-7-inhibitors-ic50-ki.
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