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Lysophosphatidic acid receptor Edg-4 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
Tetradecylphosphonic acidIC505500.0 [1]
Tetradecylphosphonic acidKi3550.0 [1]
3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-acrylic acidIC5022.0 [1]
3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-acrylic acidKi20.8 [1]
3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acidIC509.0 [1]
3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acidKi7.2 [1]
(4'-(4-((R)-1-(2-Chlorophenyl)ethoxycarbonylamino)-3-methylisoxazol-5-yl)biphenyl-4-yl)acetic acidIC501700.0 [1]
LPA2 antagonist 1IC5017.0 [1]
AM095 free acidIC508000.0 [1]
TC Lpa5 4IC5010000.0 [1]
[3-(4-Nonyl-benzylamino)-propyl]-phosphonic acidIC5040.0 [1]
CID 66775043IC508600.0 [1]
3-(3-Bromo-5-methoxy-4-(octyloxy)benzylamino)propylphosphonic acidIC5080.0 [1]
[3-(4-Octyl-benzylamino)-propyl]-phosphonic acidIC5026.0 [1]
[1-Bromo-(3S)-hydrox-4-(palmitoyloxy)butyl]phosphateKi170.0 [1]
N-[3-(4-Carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
2-[4-[[(3,5-Dimethoxybenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]benzoic acidIC5050000.0 [1]
[3-(3-Chloro-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC5055.0 [1]
[3-(3-Ethoxy-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC50420.0 [1]
[3-(3-Methyl-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC5032.0 [1]
[3-(3,5-Dichloro-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC506.6 [1]
[3-(4-Octyloxy-benzylamino)-propyl]-phosphonic acidIC50530.0 [1]
[3-(4-Nonanoyl-benzylamino)-propyl]-phosphonic acidIC50250.0 [1]
[3-(4-Nonyloxy-benzylamino)-propyl]-phosphonic acidIC5074.0 [1]
[3-(3-Methoxy-5-methyl-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC5089.0 [1]
[3-(3-Chloro-5-methoxy-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC5057.0 [1]
[3-(3-Bromo-5-methoxy-4-undecyloxy-benzylamino)-propyl]-phosphonic acidIC5042.0 [1]
[3-(3-Fluoro-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC5059.0 [1]
4-[(3-Phosphono-propylamino)-methyl]-benzoic acid heptyl esterIC50700.0 [1]
{3-[4-(1-Hydroxy-nonyl)-benzylamino]-propyl}-phosphonic acidIC502100.0 [1]
[3-(3-Methoxy-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC50450.0 [1]
3-[[4-(4-Hexylphenyl)phenyl]methylamino]propylphosphonic acidIC50120.0 [1]
[3-(3-Bromo-4-heptyloxy-5-methoxy-benzylamino)-propyl]-phosphonic acidIC5033.0 [1]
[3-(3,5-Dibromo-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC5023.0 [1]
[3-(3-Hydroxy-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC501200.0 [1]
[3-(3,5-Dimethyl-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC5015.0 [1]
[3-(3-Bromo-4-octyloxy-benzylamino)-propyl]-phosphonic acidIC5036.0 [1]
[3-(3-Bromo-4-decyloxy-5-methoxy-benzylamino)-propyl]-phosphonic acidIC5018.0 [1]
E,E-3-[4'-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarbamoyl]-acrylic acidKi21.1 [1]
N-[3,5-Bis(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
N-[3-(4-Cyanophenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC5026000.0 [1]
N-[3-(3-Carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
N-[3-[4-(Dimethylcarbamoyl)phenoxy]-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-4-yloxyphenyl]-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-3-yloxyphenyl]-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-2-yloxyphenyl]-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
3-[[4-(5-Heptyl-1,2,4-oxadiazol-3-yl)phenyl]methylamino]propylphosphonic acidIC50120.0 [1]
{3-[4-(2-Heptyl-2H-tetrazol-5-yl)-benzylamino]-propyl}-phosphonic acidIC50270.0 [1]
7-Methyl-N-[(2S)-1-[4-(2-methylphenyl)piperazin-1-yl]propan-2-yl]thieno[3,2-d]pyrimidin-4-amineIC50260.0 [1]
N-[(2S)-1-[4-(3-Chlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amineIC5035.0 [1]
7-Methyl-N-[(2S)-1-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]propan-2-yl]thieno[3,2-d]pyrimidin-4-amineIC50170.0 [1]
7-Methyl-N-[(2S)-1-[4-(3-methylphenyl)sulfonylpiperazin-1-yl]propan-2-yl]thieno[3,2-d]pyrimidin-4-amineIC50310.0 [1]
N-[(2S)-1-(4-Benzylsulfonylpiperazin-1-yl)propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amineIC501860.0 [1]
7-Methyl-N-[(2S)-1-[4-(2-methylphenyl)sulfonylpiperazin-1-yl]propan-2-yl]thieno[3,2-d]pyrimidin-4-amineIC50730.0 [1]
N-[(2S)-1-(4-Butylsulfonylpiperazin-1-yl)propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amineIC506610.0 [1]
N-[(2S)-1-[4-(2-Methylphenyl)piperazin-1-yl]propan-2-yl]-2-(trifluoromethyl)quinazolin-4-amineIC50730.0 [1]
N-[1-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-methylpropan-2-yl]-2-(trifluoromethyl)quinazolin-4-amineIC5030000.0 [1]
N-[(2S)-1-[4-(2-Methoxyphenyl)piperazin-1-yl]butan-2-yl]-2-(trifluoromethyl)quinazolin-4-amineIC5030000.0 [1]
N-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-2-(trifluoromethyl)quinazolin-4-amineIC5030000.0 [1]
N-[(2R)-1-[4-(2-Methoxyphenyl)piperazin-1-yl]propan-2-yl]-2-(trifluoromethyl)quinazolin-4-amineIC5030000.0 [1]
N-[(2S)-1-[4-(2-Methoxyphenyl)piperazin-1-yl]propan-2-yl]-2-(trifluoromethyl)quinazolin-4-amineIC501300.0 [1]
2-Cyclopropyl-N-[(2S)-1-[4-(2-methoxyphenyl)piperazin-1-yl]propan-2-yl]quinazolin-4-amineIC503200.0 [1]
1-Phenylethyl N-(3-methyl-5-phenyl-1,2-oxazol-4-yl)carbamateIC5050000.0 [1]
2-Cyclopropyl-N-[1-[4-(4-fluorophenyl)piperazin-1-yl]propan-2-yl]quinazolin-4-amineIC501700.0 [1]
2-[4-[[(3,5-Dimethoxy-4-methylbenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]acetic acidIC5023000.0 [1]
5-Chloro-2-[4-[[(3,5-dimethoxy-4-methylbenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]benzoic acidIC50790.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-(4-sulfamoylphenoxy)phenyl]-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-[4-(methylcarbamoyl)phenoxy]phenyl]-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
N-[3-(2-Carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-(4-methylsulfonylphenoxy)phenyl]-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
[3-(3-Bromo-4-hexyloxy-5-methoxy-benzylamino)-propyl]-phosphonic acidIC50260.0 [1]
Sodium;[(3S)-1-bromo-3-hydroxy-4-[(Z)-octadec-9-enoyl]oxybutyl]-hydroxyphosphinateKi170.0 [1]
[(3S)-1-Bromo-4-[(Z)-hexadec-9-enoyl]oxy-3-hydroxybutyl]phosphonic acidIC501420.0 [1]
(2-Dodecyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphateIC507430.0 [1]
2-(4-Butoxyphenyl)sulfanyl-5-[2-(1-hydroxytridec-2-ynyl)phenyl]benzenesulfonic acidIC5040000.0 [1]
2-(4-Butoxyphenyl)sulfanyl-5-[2-[1-hydroxy-4-(7-hydroxyheptoxy)but-2-ynyl]phenyl]benzenesulfonic acidIC506000.0 [1]
Items per page: 1 - 10 of 76
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lysophosphatidic acid receptor Edg-4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/lysophosphatidic-acid-receptor-edg-4-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Lysophosphatidic acid receptor Edg-4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysophosphatidic-acid-receptor-edg-4-inhibitors-ic50-ki.
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