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Lysine-specific demethylase 6B Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Pyridine-2,4-dicarboxylic acidIC5031622.78 [1], 44600.0 [2]
8-Hydroxy-5-quinolinecarboxylic acidIC50100.0 [1], 140.0 [2]
3-[[2-Pyridin-2-Yl-6-(1,2,4,5-Tetrahydro-3-Benzazepin-3-Yl)pyrimidin-4-Yl]amino]propanoic AcidIC5063.1 [1], 150.0 [2]
3-Aminoisonicotinic acidIC5063095.73 [1]
4-Oxo-4-[4-[4-(1-naphthylcarbamoyloxymethyl)benzylamino]butylhydroxyamino]-2-butenoic acidIC503100.0 [1], 43000.0 [2]
N-OxalylglycineIC50316.23 [1]
4,6-Dioxoheptanoic acidIC5016500.0 [1]
DaminozideIC50100000.0 [1]
Tranylcypromine hydrochlorideIC50100000.0 [1]
(E)-5-Chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridineIC50794.33 [1]
4-(Hydroxyamino)-4-oxobutanoic acidIC501100.0 [1]
2-{5-[(4-Chloro-2-Methylphenyl)methoxy]-1h-Pyrazol-1-Yl}pyridine-4-Carboxylic AcidIC502300.0 [1]
3-[[(1R)-6-(N-Methylanilino)-1,2,3,4-tetrahydronaphthalen-1-yl]methylamino]pyridine-4-carboxylic acidIC504000.0 [1]
2-[(1-Benzyl-1h-Pyrazol-4-Yl)oxy]pyrido[3,4-D]pyrimidin-4(3h)-OneIC50100000.0 [1]
2-(((2-((2-(Dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acidIC501000.0 [1]
2,2'-Bipyridine-4-carboxylic acidIC5010000.0 [1]
2-[1-[(3R)-1-Benzoylpiperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[(3S)-1-Benzoylpiperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC5031622.78 [1]
2-[(3-Methylthiophen-2-yl)methylamino]pyridine-3-carboxylic acidIC50100000.0 [1]
(E)-5-[Hydroxy-[4-[[4-(naphthalen-1-ylcarbamoyloxymethyl)phenyl]methylamino]butyl]amino]-4-oxopent-2-enoic acidIC5039810.72 [1]
2-[1-(2-Phenylethyl)triazol-4-yl]pyridine-4-carboxylic acidIC5079432.82 [1]
2-[1-(2-Phenoxyethyl)triazol-4-yl]pyridine-4-carboxylic acidIC5079432.82 [1]
2-[1-(1-Ethoxycarbonylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Propanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5063095.73 [1]
2-[1-(1-Butanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Benzoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5039810.72 [1]
2-[1-[1-(2-Phenylacetyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acidIC5015848.93 [1]
2-[1-[1-(3-Phenylpropanoyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Acetylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Propanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5050118.72 [1]
2-[1-(1-Butanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5063095.73 [1]
2-[1-(1-Benzoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(2-Phenylacetyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(3-Phenylpropanoyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Butanoylpyrrolidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(2-Phenylacetyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC5050118.72 [1]
2-[1-[1-(3-Phenylpropanoyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC5079432.82 [1]
2-[1-(1-Acetylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Propanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5050118.72 [1]
2-[1-(1-Butanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5079432.82 [1]
2-[1-(1-Benzoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5019952.62 [1]
2-[1-[1-(2-Phenylacetyl)piperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC5012589.25 [1]
2-[1-[1-(3-Phenylpropanoyl)piperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC5012589.25 [1]
5-Chloro-7-[benzoylamino(3-methyl-2-thienyl)methyl]-8-quinolinolIC50106000.0 [1]
Octyl 8-hydroxyquinoline-5-carboxylateIC50100000.0 [1]
3-[[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-6-pyrazol-1-ylpyrimidin-2-yl]amino]propanoic acidIC50490.0 [1]
3-[[4-[4-(2-Methoxyphenyl)piperazin-1-yl]-6-pyrazol-1-ylpyrimidin-2-yl]amino]propanoic acidIC5020000.0 [1]
3-[[4-(1,2,4,5-Tetrahydro-3-benzazepin-3-yl)-6-(triazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC50270.0 [1]
3-[[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-6-(triazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC501500.0 [1]
3-[[4-(4-Pyridin-2-ylpiperazin-1-yl)-6-(triazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC501300.0 [1]
3-[[4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]-6-(triazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC501400.0 [1]
3-[[4-(4-Phenylpiperidin-1-yl)-6-(triazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC501200.0 [1]
3-[[4-(1,2,4,5-Tetrahydro-3-benzazepin-3-yl)-6-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC50200.0 [1]
3-[[4-(4-Phenylpiperidin-1-yl)-6-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC501200.0 [1]
3-[[4-[4-(4-Fluorophenyl)piperazin-1-yl]-6-(triazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC502600.0 [1]
3-[[4-Pyrazol-1-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-2-yl]amino]propanoic acidIC50150.0 [1]
3-[[4-(4-Phenylpiperidin-1-yl)-6-pyrazol-1-ylpyrimidin-2-yl]amino]propanoic acidIC50750.0 [1]
3-[[4-[4-(4-Fluorophenyl)piperazin-1-yl]-6-pyrazol-1-ylpyrimidin-2-yl]amino]propanoic acidIC50550.0 [1]
3-[[4-Pyrazol-1-yl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidin-2-yl]amino]propanoic acidIC501000.0 [1]
3-[[4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]-6-pyrazol-1-ylpyrimidin-2-yl]amino]propanoic acidIC50740.0 [1]
3-[[4-[4-(2-Methoxyphenyl)piperazin-1-yl]-6-(triazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC5020000.0 [1]
3-[[4-(1,2,4,5-Tetrahydro-3-benzazepin-3-yl)-6-(triazol-1-yl)pyrimidin-2-yl]amino]propanoic acidIC50210.0 [1]
3-[[4-(4-Phenylpiperidin-1-yl)-6-(triazol-1-yl)pyrimidin-2-yl]amino]propanoic acidIC502100.0 [1]
3-[[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-6-(triazol-1-yl)pyrimidin-2-yl]amino]propanoic acidIC501400.0 [1]
3-[[4-[4-(4-Fluorophenyl)piperazin-1-yl]-6-(triazol-1-yl)pyrimidin-2-yl]amino]propanoic acidIC5010000.0 [1]
3-[[4-[4-(2-Methoxyphenyl)piperazin-1-yl]-6-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC502100.0 [1]
3-[[4-[4-(4-Fluorophenyl)piperazin-1-yl]-6-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC50600.0 [1]
3-[[4-(4-Pyridin-2-ylpiperazin-1-yl)-6-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC50900.0 [1]
3-[[4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]-6-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC50940.0 [1]
3-[[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-6-indazol-2-ylpyrimidin-2-yl]amino]propanoic acidIC506100.0 [1]
3-[[4-Indazol-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-2-yl]amino]propanoic acidIC502200.0 [1]
3-[[4-[4-(4-Fluorophenyl)piperazin-1-yl]-6-indazol-2-ylpyrimidin-2-yl]amino]propanoic acidIC505800.0 [1]
3-[[4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]-6-indazol-2-ylpyrimidin-2-yl]amino]propanoic acidIC50100000.0 [1]
3-[[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]propanoic acidIC50990.0 [1]
2-[5-(2-Methoxyethanoylamino)-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic AcidIC50100000.0 [1]
2-[5-[(5-Methyl-1,2-oxazol-3-yl)carbonylamino]-2-oxidanyl-phenyl]pyridine-4-carboxylic acidIC5031000.0 [1]
2-(5-Acetamido-2-Oxidanyl-Phenyl)pyridine-4-Carboxylic AcidIC50100000.0 [1]
2-[5-[(4-Hydroxyphenyl)carbonylamino]-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic AcidIC5027000.0 [1]
2-[5-[2-(3-Methoxyphenyl)ethanoylamino]-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic AcidIC5016000.0 [1]
8-[4-[2-[(4-Fluorophenyl)methyl-Methyl-Amino]ethyl]pyrazol-1-Yl]-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC5026300.0 [1]
8-[4-[2-[4-[(4-Chlorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5048500.0 [1]
2-[1-(Cyclohexylmethyl)pyrazol-4-yl]oxy-3H-pyrido[3,4-d]pyrimidin-4-oneIC50100000.0 [1]
2-(1-Cyclopentylpyrazol-4-yl)oxy-3H-pyrido[3,4-d]pyrimidin-4-oneIC50100000.0 [1]
2-(4-Chloro-3-hydroxyphenoxy)-3H-pyrido[3,4-d]pyrimidin-4-oneIC50100000.0 [1]
2-(1-Benzylpyrazol-4-yl)oxy-3H-pyrido[2,3-d]pyrimidin-4-oneIC50100000.0 [1]
4-Hydrazinyl-4-oxobutanoic acidIC50100000.0 [1]
N'1,N'1,N'4,N'4-TetramethylsuccinohydrazideIC50100000.0 [1]
4-(Isopropylamino)-4-oxobutanoic acidIC50100000.0 [1]
4'-(Methoxycarbonyl)-[2,2'-bipyridine]-4-carboxylic acidIC5011200.0 [1]
Tetrazole-5-acetohydrazideIC5098000.0 [1]
3-(3-Phenylpropanamido)isonicotinic acidIC5039810.72 [1]
3-Benzamidopyridine-4-carboxylic acidIC50100000.0 [1]
3-(4-Phenylbutanoylamino)pyridine-4-carboxylic acidIC501258.93 [1]
3-[(2-Phenylacetyl)amino]pyridine-4-carboxylic acidIC503981.07 [1]
4-((Dimethylamino)oxy)-4-oxobutanoic acidIC5041700.0 [1]
4-[Dimethylamino(methyl)amino]-4-oxobutanoic acidIC50100000.0 [1]
(3-Carboxypropanoylamino)-trimethylazaniumIC50100000.0 [1]
4-(2-Methylhydrazinyl)-4-oxobutanoic acidIC50100000.0 [1]
(E)-4-[4-[[4-(Aminomethyl)phenyl]methylamino]butyl-hydroxyamino]-4-oxobut-2-enoic acidIC507300.0 [1]
3-(3-Phenylpropylamino)pyridine-4-carboxylic acidIC50794.33 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lysine-specific demethylase 6B Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/lysine-specific-demethylase-6b-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Lysine-specific demethylase 6B Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysine-specific-demethylase-6b-inhibitors-ic50-ki.
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