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Lysine-specific demethylase 5A/5B Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
2-{5-[(4-Chloro-2-Methylphenyl)methoxy]-1h-Pyrazol-1-Yl}pyridine-4-Carboxylic AcidIC50100.0 [1]
2-[5-(4-Methoxyphenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(4-Chlorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-(1-Methylimidazol-4-yl)pyridine-4-carboxylic acidIC5010000.0 [1]
2-(5-(Benzyloxy)-1H-pyrazol-1-yl)isonicotinic acidIC501000.0 [1]
2-[5-[(4-Cyanophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(4-Chloro-2-methoxyphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(4-Bromophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(4-Chloro-2-fluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(4-Methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
Methyl 2-[5-[(4-chlorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylateIC50100.0 [1]
2-[5-[(4-Ethylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(4-Chloro-2-ethoxyphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(3-Fluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[5-[(4-Fluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-(1-Methylimidazol-4-yl)-4-(2H-tetrazol-5-yl)pyridineIC5010000.0 [1]
2-[5-[4-(Cyclopropylmethoxy)phenyl]-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
CID 85470886IC501000.0 [1]
2-[5-(3-Hydroxy-4-methylphenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
CID 86269080IC501000.0 [1]
CID 86269285IC501000.0 [1]
CID 86269286IC501000.0 [1]
2-[1-[2-(2-Methoxyphenyl)ethyl]imidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[1-[2-(2-Methylphenyl)ethyl]imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[1-[2-(2-Chlorophenyl)ethyl]imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[1-[2-[2-(Trifluoromethyl)phenyl]ethyl]imidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
CID 86269492IC501000.0 [1]
2-[1-[(4-Fluorophenyl)methyl]imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
Methyl 2-[5-[(4-cyanophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylateIC501000.0 [1]
2-[5-[(3-Chloro-4-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(3-Fluoro-4-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(2,3-Difluoro-4-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(4-Cyano-2-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(4-Fluoro-2-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(4-Iodo-2-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(2-Methoxy-4-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(2,4-Difluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
Methyl 2-[5-[(3,4-difluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylateIC50100.0 [1]
2-[5-[(4-Ethyl-2-fluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[[4-Chloro-3-(cyclopropylmethoxy)phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[[4-Chloro-3-[(4-fluorophenyl)methoxy]phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(3,4-Dichlorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(2-Fluoro-4-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(2,2-Dimethyl-3H-1-benzofuran-7-yl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[5-[(2,4-Dimethylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[[4-Chloro-3-(2,2,2-trifluoroethoxy)phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[[4-Fluoro-2-[2-(4-fluorophenyl)ethyl]phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(3,4-Difluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(3-Chloro-4-fluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[[4-Fluoro-3-[(4-fluorophenyl)methoxy]phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
2-[5-[(4-Bromo-2-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(4-Chloro-3-fluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(2-Ethyl-4-fluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[[4-Fluoro-2-[(4-fluorophenyl)methoxy]phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(2-Chloro-4-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(1-Methylindazol-6-yl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[5-[[4-Chloro-2-[(4-fluorophenyl)methoxy]phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(4,4-Difluorocyclohexyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(4-Chloro-2-ethylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(3-Chlorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC50100.0 [1]
Methyl 2-[5-[(4-fluorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylateIC501000.0 [1]
2-[5-[(4-Cyano-2-ethylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[5-[(4-Iodo-2-methoxyphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(2-Cyano-4-methylphenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[(3-Bromophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[[4-Chloro-2-(1-phenylethoxy)phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-[[4-Fluoro-2-(1-phenylethoxy)phenyl]methoxy]pyrazol-1-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[1-(1-Phenylethyl)imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-(4-Chlorophenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-(1-Propylimidazol-4-yl)pyridine-4-carboxylic acidIC501000.0 [1]
2-[1-(2-Pyrrolidin-1-ylethyl)imidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-(1-Benzylimidazol-4-yl)pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-(4-Fluorophenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[1-[(3-Fluorophenyl)methyl]imidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[1-[2-(Dimethylamino)ethyl]imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[1-Methyl-5-(4-pyrazol-1-ylphenyl)imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[1-[(2-Fluorophenyl)methyl]imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-(1H-Indol-6-yl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[1-Methyl-5-(4-pyrrolidin-1-ylphenyl)imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-(4-Cyclopropylphenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
CID 90407508IC501000.0 [1]
2-[1-[2-(2-Chlorophenyl)-2-methylpropyl]imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[1-(1-Phenylpropan-2-yl)imidazol-4-yl]pyridine-4-carboxylic acidIC501000.0 [1]
2-[5-(4-Chloro-3-fluorophenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[5-(4-Chloro-3-fluorophenyl)-1-propylimidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[5-(3-Chlorophenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Lysine-specific demethylase 5A/5B Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/lysine-specific-demethylase-5a-5b-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ Lysine-specific demethylase 5A/5B Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysine-specific-demethylase-5a-5b-inhibitors-ic50-ki.
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