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Lysine-specific demethylase 4D-like Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
8-Hydroxy-5-quinolinecarboxylic acidIC50300.0 [1]
BaicaleinIC503000.0 [1]
BaicaleinKi4330.0 [1]
beta-LapachoneIC503000.0 [1]
beta-LapachoneKi3550.0 [1]
VorinostatIC5014000.0 [1], 540000.0 [2]
MyricetinIC503000.0 [1]
FenoldopamIC503000.0 [1]
FenoldopamKi1920.0 [1]
Pyridine-2,4-dicarboxylic acidIC506309.57 [1]
Pyridine-2,4-dicarboxylic acidKi914000.0 [1]
N,3-DihydroxybenzamideIC504800.0 [1], 28000.0 [2]
4'-[(2-Phenylethyl)carbamoyl][2,2'-Bipyridine]-4-Carboxylic AcidIC50110.0 [1]
4'-[(2-Aminoethyl)carbamoyl]-2,2'-Bipyridine-4-Carboxylic AcidIC50180.0 [1]
DopamineIC503000.0 [1]
MethyldopaIC503000.0 [1]
LodosynKi1980.0 [1]
N-OxalylglycineIC50100000.0 [1]
4,6-Dioxoheptanoic acidIC5023900.0 [1]
DaminozideIC50100000.0 [1]
Tranylcypromine hydrochlorideIC50100000.0 [1]
3-[[2-Pyridin-2-Yl-6-(1,2,4,5-Tetrahydro-3-Benzazepin-3-Yl)pyrimidin-4-Yl]amino]propanoic AcidIC5019952.62 [1]
(E)-5-Chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridineIC50316.23 [1]
5-(1-Piperidinylmethyl)-8-quinolinolIC5011000.0 [1]
5-[(2-Fluoroanilino)methyl]-8-quinolinolIC501100.0 [1]
3-Aminoisonicotinic acidIC501258.93 [1]
4-(Hydroxyamino)-4-oxobutanoic acidIC50400.0 [1]
2-{5-[(4-Chloro-2-Methylphenyl)methoxy]-1h-Pyrazol-1-Yl}pyridine-4-Carboxylic AcidIC50160.0 [1]
(R)-3-(4-(4-Bromophenylsulfonyloxy)phenyl)-2-(carboxyformamido)propanoic acidIC505400.0 [1]
4-Oxo-4-[4-[4-(1-naphthylcarbamoyloxymethyl)benzylamino]butylhydroxyamino]-2-butenoic acidIC505900.0 [1]
8-Hydroxyquinoline-4-carboxylic acidIC502000.0 [1]
2-[(1-Benzyl-1h-Pyrazol-4-Yl)oxy]pyrido[3,4-D]pyrimidin-4(3h)-OneIC50501.19 [1]
(R)-2-(Carboxyformamido)-3-(4-(4-fluorophenylsulfonyloxy)phenyl)propanoic acidIC505000.0 [1]
(R)-3-(4-(4-Tert-butylphenylsulfonyloxy)phenyl)-2-(carboxyformamido)propanoic acidIC505000.0 [1]
3-(2-Fluoroanilino)pyridine-2,4-dicarboxylic acidIC502500.0 [1]
2,2'-Bipyridine-4-carboxylic acidIC50398.11 [1]
2-[1-[(3R)-1-Benzoylpiperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[(3S)-1-Benzoylpiperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[(3-Methylthiophen-2-yl)methylamino]pyridine-3-carboxylic acidIC50100000.0 [1]
(E)-5-[Hydroxy-[4-[[4-(naphthalen-1-ylcarbamoyloxymethyl)phenyl]methylamino]butyl]amino]-4-oxopent-2-enoic acidIC506309.57 [1]
2-[1-(2-Phenylethyl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(2-Phenoxyethyl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Ethoxycarbonylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Propanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Butanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Benzoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(2-Phenylacetyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(3-Phenylpropanoyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Acetylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC505011.87 [1]
2-[1-(1-Propanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Butanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5079432.82 [1]
2-[1-(1-Benzoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5050118.72 [1]
2-[1-[1-(2-Phenylacetyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(3-Phenylpropanoyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC5025118.86 [1]
2-[1-(1-Butanoylpyrrolidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(2-Phenylacetyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(3-Phenylpropanoyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Acetylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Propanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Butanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-(1-Benzoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(2-Phenylacetyl)piperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
2-[1-[1-(3-Phenylpropanoyl)piperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC50100000.0 [1]
5-Chloro-7-[benzoylamino(3-methyl-2-thienyl)methyl]-8-quinolinolIC505000.0 [1]
Octyl 8-hydroxyquinoline-5-carboxylateIC5045000.0 [1]
2-[1-(Cyclohexylmethyl)pyrazol-4-yl]oxy-3H-pyrido[3,4-d]pyrimidin-4-oneIC50501.19 [1]
2-(1-Cyclopentylpyrazol-4-yl)oxy-3H-pyrido[3,4-d]pyrimidin-4-oneIC50398.11 [1]
2-(6-Propan-2-ylpyridin-3-yl)oxy-3H-pyrido[3,4-d]pyrimidin-4-oneIC50398.11 [1]
2-(4-Chloro-3-hydroxyphenoxy)-3H-pyrido[3,4-d]pyrimidin-4-oneIC50125.89 [1]
2-(1-Benzylpyrazol-4-yl)oxy-3H-pyrido[2,3-d]pyrimidin-4-oneIC50100000.0 [1]
4-Hydrazinyl-4-oxobutanoic acidIC50200.0 [1]
N'1,N'1,N'4,N'4-TetramethylsuccinohydrazideIC50100000.0 [1]
4-(Isopropylamino)-4-oxobutanoic acidIC50100000.0 [1]
4'-(Methoxycarbonyl)-[2,2'-bipyridine]-4-carboxylic acidIC505000.0 [1]
2-[(2-Furylmethyl)amino]nicotinic acidIC50100000.0 [1]
(2S)-3-Benzylsulfanyl-2-(oxaloamino)propanoic acidIC50200000.0 [1]
(2S)-3-[(2-Methoxyphenyl)methylsulfanyl]-2-(oxaloamino)propanoic acidIC50200000.0 [1]
4-((Dimethylamino)oxy)-4-oxobutanoic acidIC50100000.0 [1]
4-[Dimethylamino(methyl)amino]-4-oxobutanoic acidIC50100000.0 [1]
(3-Carboxypropanoylamino)-trimethylazaniumIC50100000.0 [1]
4-(2-Methylhydrazinyl)-4-oxobutanoic acidIC504300.0 [1]
3-(Benzylamino)pyridine-4-carboxylic acidIC5039.81 [1]
3-{[(Furan-2-yl)methyl]amino}pyridine-4-carboxylic acidIC5039.81 [1]
2-Hydrazinylpyrimidine-4-carboxylic acidIC5013000.0 [1]
3-[(3-Methylthiophen-2-yl)methylamino]pyridine-4-carboxylic acidIC5050.12 [1]
2-(2h-1,2,3-Triazol-4-Yl)pyridine-4-Carboxylic AcidIC5015848.93 [1]
2-(1-Methyltriazol-4-yl)pyridine-4-carboxylic acidIC5079432.82 [1]
2-(1-Ethyltriazol-4-yl)pyridine-4-carboxylic acidIC5079432.82 [1]
2-[1-(3-Methylphenyl)triazol-4-yl]pyridine-4-carboxylic acidIC5050118.72 [1]
2-(1-Benzyltriazol-4-yl)pyridine-4-carboxylic acidIC50100000.0 [1]
N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]-8-hydroxyquinoline-5-carboxamideIC503900.0 [1]
2-[4-[[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]carbamoyl]pyridin-2-yl]pyridine-4-carboxylic acidIC50420.0 [1]
N-[4-[4-[(1R,2S)-2-Aminocyclopropyl]anilino]-4-oxobutyl]-8-hydroxyquinoline-5-carboxamideIC505500.0 [1]
Methyl 2-[4-[[4-[(1S,2R)-2-aminocyclopropyl]phenyl]carbamoyl]pyridin-2-yl]pyridine-4-carboxylateIC5016000.0 [1]
N-[6-[4-[(1R,2S)-2-Aminocyclopropyl]anilino]-6-oxohexyl]-8-hydroxyquinoline-5-carboxamideIC505100.0 [1]
N-[5-[4-[(1R,2S)-2-Aminocyclopropyl]anilino]-5-oxopentyl]-8-hydroxyquinoline-5-carboxamideIC503500.0 [1]
Items per page: 1 - 10 of 96
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lysine-specific demethylase 4D-like Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/lysine-specific-demethylase-4d-like-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Lysine-specific demethylase 4D-like Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysine-specific-demethylase-4d-like-inhibitors-ic50-ki.
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