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Long-chain fatty acid transport protein 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
N-[[4-Ethyl-5-[[5-(trifluoromethoxy)-1,3-benzoxazol-2-yl]methylsulfanyl]-1,2,4-triazol-3-yl]methyl]anilineIC50100.0 [1]
2-[4-(4-Fluorophenyl)piperazin-1-yl]-N-(1,3-thiazol-2-yl)acetamideIC501000.0 [1]
CID 71601847IC5046.0 [1]
2-{[4-Allyl-5-(anilinomethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-methoxyphenyl)acetamideIC506600.0 [1]
2-(4-Phenylpiperazin-1-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC50280.0 [1]
2-[4-(4-Fluorophenyl)piperazin-1-yl]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC5077.0 [1]
N-(4,5-Dimethyl-1,3-thiazol-2-yl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamideIC50430.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(6-propanoylpyridin-3-yl)acetamideIC50400.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-methyl-N-(4-propanoylphenyl)acetamideIC50580.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-ethyl-N-(4-propanoylphenyl)acetamideIC501000.0 [1]
Ethyl 1-[2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]-3,4-dihydro-2H-quinoline-6-carboxylateIC501000.0 [1]
Ethyl 1-[2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]-2,3-dihydroindole-5-carboxylateIC501000.0 [1]
Ethyl 4-[[2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoateIC50330.0 [1]
Ethyl 3-[[2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoateIC501000.0 [1]
Methyl 4-[[2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoateIC50540.0 [1]
Tert-butyl 4-[[2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoateIC501000.0 [1]
4-[[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoic acidIC501000.0 [1]
4-[[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]-N-methylbenzamideIC501000.0 [1]
4-[[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]-N,N-dimethylbenzamideIC501000.0 [1]
4-[[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]-N-ethylbenzamideIC501000.0 [1]
1-[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-benzoxazol-5-yl]propan-1-oneIC50190.0 [1]
Ethyl 2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-benzoxazole-5-carboxylateIC50680.0 [1]
1-[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-benzoxazol-6-yl]propan-1-oneIC50900.0 [1]
1-[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfonylmethyl]-1,3-benzoxazol-5-yl]propan-1-oneIC501670.0 [1]
1-[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-benzoxazol-5-yl]propan-1-olIC501000.0 [1]
(NZ)-N-[1-[2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-benzoxazol-5-yl]propylidene]hydroxylamineIC50260.0 [1]
N-[[4-Ethyl-5-[[5-[(Z)-C-ethyl-N-methoxycarbonimidoyl]-1,3-benzoxazol-2-yl]methylsulfanyl]-1,2,4-triazol-3-yl]methyl]anilineIC501000.0 [1]
N-[[4-Ethyl-5-[[5-(trifluoromethyl)-1,3-benzoxazol-2-yl]methylsulfanyl]-1,2,4-triazol-3-yl]methyl]anilineIC50360.0 [1]
1-[2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-benzoxazol-5-yl]-2-methylpropan-1-oneIC50600.0 [1]
N-(1,3-Benzothiazol-2-yl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamideIC50490.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methylsulfonylphenyl)acetamideIC501000.0 [1]
N-[[5-[(6-Chloro-1,3-benzoxazol-2-yl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]anilineIC501000.0 [1]
N-[[4-Ethyl-5-[(5-ethyl-1,3-benzoxazol-2-yl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]anilineIC501000.0 [1]
N-[[4-Ethyl-5-[(5-methoxy-1,3-benzoxazol-2-yl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]anilineIC501000.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methoxyphenyl)acetamideIC501000.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-chlorophenyl)acetamideIC501000.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-propanoylphenyl)acetamideIC50400.0 [1]
N-[[5-(1,3-Benzoxazol-2-ylmethylsulfanyl)-4-ethyl-1,2,4-triazol-3-yl]methyl]anilineIC501000.0 [1]
N-[[4-Ethyl-5-[(5-fluoro-1,3-benzoxazol-2-yl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]anilineIC501000.0 [1]
N-[[5-[(5-Chloro-1,3-benzoxazol-2-yl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]anilineIC501000.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-phenylacetamideIC501000.0 [1]
N-(4-Acetylphenyl)-2-[[5-(anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamideIC501000.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-benzoylphenyl)acetamideIC501000.0 [1]
N-[[4-Ethyl-5-[(5-methyl-1,3-benzoxazol-2-yl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]anilineIC501000.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-cyanophenyl)acetamideIC501000.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-[4-(2-ethyltetrazol-5-yl)phenyl]acetamideIC501000.0 [1]
2-[[5-(Anilinomethyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-butanoylphenyl)acetamideIC50230.0 [1]
2-[4-(4-Fluorophenyl)piperazin-1-yl]-N-(4,5,6,7-tetrahydro-1,3-benzoxazol-2-yl)acetamideIC50180.0 [1]
N-(5,6-Dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamideIC50490.0 [1]
2-[4-(4-Fluorophenyl)piperazin-1-yl]-N-(5,6,7,8-tetrahydro-4H-cyclohepta[d][1,3]thiazol-2-yl)acetamideIC50120.0 [1]
2-[4-(4-Methylphenyl)piperazin-1-yl]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC50250.0 [1]
2-[4-(3-Fluorophenyl)piperazin-1-yl]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC501000.0 [1]
2-(4-Benzoylpiperazin-1-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC501000.0 [1]
2-(4-Cyclohexylpiperazin-1-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC501000.0 [1]
2-(4-Pyridin-2-ylpiperazin-1-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC50200.0 [1]
2-(4-Pyridin-3-ylpiperazin-1-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC501000.0 [1]
2-(4-Pyridin-4-ylpiperazin-1-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC501000.0 [1]
2-(4-Pyrimidin-2-ylpiperazin-1-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC501000.0 [1]
N-(4,5,6,7-Tetrahydro-1,3-benzothiazol-2-yl)-2-[4-(1,3-thiazol-2-yl)piperazin-1-yl]acetamideIC50520.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-N-(4,5,6,7-tetrahydro-1,3-benzoxazol-2-yl)acetamideIC50100.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-N-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC5041.0 [1]
N-Ethyl-2-[4-(5-fluoropyridin-2-yl)piperazin-1-yl]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC50780.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-1-(2-methylimidazo[1,2-a]pyridin-3-yl)ethanoneIC50430.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-1-imidazo[1,2-a]pyridin-3-ylethanoneIC50130.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-1-imidazo[1,5-a]pyridin-3-ylethanoneIC501000.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-1-(1H-indazol-3-yl)ethanoneIC501000.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-1-pyrazolo[1,5-a]pyridin-3-ylethanoneIC50330.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-1-(1H-indol-3-yl)ethanoneIC501000.0 [1]
1-(1-Benzofuran-3-yl)-2-[4-(5-fluoropyridin-2-yl)piperazin-1-yl]ethanoneIC50470.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-1-(2-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl)ethanoneIC50190.0 [1]
2-[4-(5-Fluoropyridin-2-yl)piperazin-1-yl]-1-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl)ethanoneIC50100.0 [1]
2-[4-(4-Fluorophenyl)piperazin-1-yl]-N-(5-methyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideIC5026.0 [1]
1-(2-Methylimidazo[1,2-a]pyridine-3-yl)-2-(4-phenylpiperazino)ethanoneIC503000.0 [1]
Ethyl 4-{[({5-[(benzylsulfanyl)methyl]-4-ethyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetyl]amino}benzoateIC507600.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Long-chain fatty acid transport protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/long-chain-fatty-acid-transport-protein-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ Long-chain fatty acid transport protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/long-chain-fatty-acid-transport-protein-1-inhibitors-ic50-ki.
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