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Lipoprotein lipase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
p-Tolylboronic acidIC509000.0 [1], 25000.0 [2]
4-Nonylphenylboronic acidIC501400.0 [1], 42000.0 [2]
4-Ethylphenylboronic acidIC509000.0 [1], 20000.0 [2]
2-([1,1'-Biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneIC504400.0 [1], 12000.0 [2]
4-Undecylphenylboronic AcidIC501500.0 [1], 50000.0 [2]
2-[4-(Fur-2-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneIC509600.0 [1], 35000.0 [2]
4-Propylphenylboronic acidIC508000.0 [1], 12500.0 [2]
(4-Heptylphenyl)boronic AcidIC509000.0 [1], 30000.0 [2]
(4-Pentylphenyl)boronic AcidIC503800.0 [1], 15000.0 [2]
4,4,5,5-Tetramethyl-2-(4-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolaneIC5015000.0 [1], 22000.0 [2]
2-[4-(Furan-3-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneIC5015000.0 [1], 33000.0 [2]
4,4,5,5-Tetramethyl-2-(4-nonylphenyl)-1,3,2-dioxaborolaneIC5015000.0 [1], 50000.0 [2]
3-Pentylphenylboronic AcidIC5050000.0 [1], 85000.0 [2]
2-(4-Heptylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneIC5019000.0 [1], 55000.0 [2]
3-Nonylphenylboronic AcidIC5050000.0 [1], 95000.0 [2]
4,4,5,5-Tetramethyl-2-(4-pentylphenyl)-1,3,2-dioxaborolaneIC5021000.0 [1], 50000.0 [2]
2-[4-(4-Fluorophenyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneIC5033000.0 [1], 55000.0 [2]
4,4,5,5-Tetramethyl-2-(4-undecylphenyl)-1,3,2-dioxaborolaneIC5015000.0 [1], 50000.0 [2]
4,4,5,5-Tetramethyl-2-(4-propylphenyl)-1,3,2-dioxaborolaneIC5025000.0 [1]
4,4,5,5-Tetramethyl-2-(4-thiophen-3-ylphenyl)-1,3,2-dioxaborolaneIC5013000.0 [1], 36000.0 [2]
2-Nonylphenylboronic AcidIC5050000.0 [1], 500000.0 [2]
3-[3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]phenyl]propanoic acidIC50120000.0 [1], 500000.0 [2]
4,4,5,5-Tetramethyl-2-(3-pentylphenyl)-1,3,2-dioxaborolaneIC5045000.0 [1], 100000.0 [2]
4,4,5,5-Tetramethyl-2-(4-(thiophen-2-yl)phenyl)-1,3,2-dioxaborolaneIC507000.0 [1], 40000.0 [2]
2-[(3S)-3-(Pyridin-2-ylmethoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5020000.0 [1]
(S)-4-Isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-oneIC5050000.0 [1]
N-Methyl-5-methylsulfanyl-N-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazole-1-carboxamideIC5050000.0 [1]
3-(4-Chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trifluoroethylsulfanyl)-1,2,4-triazole-1-carboxamideIC5050000.0 [1]
4-Tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazol-3-yl)-phenyl]-benzamideIC50200.0 [1]
3-(3-(Benzyloxy)phenyl)-5-ethoxy-1,3,4-oxadiazol-2(3H)-oneIC5010000.0 [1]
N-[3-(3,4-Dichlorophenyl)propyl]-4-hydroxy-1-methyl-5-oxo-2H-pyrrole-3-carboxamideIC5037000.0 [1]
2-(Cyclopropylmethylamino)-5-(trifluoromethyl)benzoic acidIC5010000.0 [1]
S-[(2-Fluorophenyl)methyl] N-(6-phenylhexyl)carbamothioateIC501690.0 [1]
2-[(3S)-3-(4-Fluorophenoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC50100000.0 [1]
2-[(3R)-3-(4-Fluorophenoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5033000.0 [1]
2-[3-[(4-Fluorophenyl)methyl]pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC502560.0 [1]
5-(Trifluoromethyl)-2-[(3S)-3-[5-(trifluoromethyl)pyridin-2-yl]oxypyrrolidin-1-yl]benzoic acidIC5020000.0 [1]
2-[(3S)-3-(6-Chloropyridin-3-yl)oxypyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5031590.0 [1]
2-[(3S)-3-[(4-Fluorophenyl)methoxy]pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5033000.0 [1]
2-[(3S)-3-(Cyclopropylmethoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5049900.0 [1]
2-[(3S)-3-(2-Cyclopropylethoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5033000.0 [1]
2-[(3S)-3-Butoxypyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC50100000.0 [1]
2-[(3S)-3-[(5-Fluoropyridin-2-yl)methoxy]pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5076300.0 [1]
2-[(3S)-3-[(3-Fluoropyridin-2-yl)methoxy]pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5077200.0 [1]
2-[(3S)-3-[(5-Fluoropyridin-3-yl)methoxy]pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5045200.0 [1]
2-[(3S)-3-(2-Phenylmethoxyethoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC5033000.0 [1]
2-[(3S)-3-(2-Ethoxyethoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC50100000.0 [1]
2-[(3S)-3-[2-(2-Methoxyethoxy)ethoxy]pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acidIC50100000.0 [1]
N-[3-(3,4-Dichlorophenyl)propyl]-3-hydroxy-1-methyl-2-oxopyridine-4-carboxamideIC5090000.0 [1]
Items per page: 1 - 10 of 49
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lipoprotein lipase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/lipoprotein-lipase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Lipoprotein lipase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lipoprotein-lipase-inhibitors-ic50-ki.
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