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Leukotriene A4 hydrolase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
UbenimexIC504000.0 [1]
UbenimexKi320.0 [1]
CaptoprilIC5070.0 [1], 3600.0 [2], 10000.0 [3], 14000.0 [4]
CaptoprilKi3700.0 [1]
KelatorphanIC505.0 [1], 50000.0 [2]
KelatorphanKi10.0 [1], 18.0 [2]
N-[3-(4-Benzylphenoxy)propyl]-N-Methyl-beta-AlanineIC502.5 [1], 6.0 [2], 49.0 [3]
N-[3-(4-Benzylphenoxy)propyl]-N-Methyl-beta-AlanineKi3.0 [1]
2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl}-oxazoleIC5043.0 [1], 55.0 [2]
5-Benzyloxy-DL-tryptophanIC5017300.0 [1], 231000.0 [2]
1-[2-(4-Phenylphenoxy)ethyl]pyrrolidineIC50200.0 [1], 790.0 [2]
1-[2-(4-Benzylphenoxy)ethyl]pyrrolidineIC5026.0 [1], 120.0 [2]
4-(4-Benzylphenyl)-1,3-thiazol-2-amineIC50400.0 [1], 7610.0 [2], 12400.0 [3]
4-(4-Benzylphenyl)-1,3-thiazol-2-amineKi360.0 [1]
1-[2-(4-Phenoxyphenoxy)ethyl]pyrrolidineIC5030.0 [1], 79.0 [2], 780.0 [3]
2-(4-Phenoxyphenoxy)ethanamineIC5035.0 [1], 228.0 [2]
4-((4-(Methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)amino)piperidin-1-yl)methyl)benzoic acidIC5060.0 [1], 270.0 [2]
1-(4-Thiophen-2-ylphenyl)methanamineIC5098000.0 [1], 106000.0 [2]
(4-Fluorophenyl)(pyridin-4-yl)methanoneIC503673000.0 [1], 5308000.0 [2], 5380000.0 [3]
3-[[3-(4-Benzylphenoxy)propyl]amino]propionic acidIC50140.0 [1], 280.0 [2]
2-(4-Benzylphenoxy)ethanamineIC509.0 [1], 280.0 [2]
1-[2-(4-Phenylmethanesulfonyl-phenoxy)-ethyl]-pyrrolidineIC504000.0 [1], 7700.0 [2]
1-[2-(4-Benzylphenoxy)ethyl]piperidineIC5055.0 [1], 170.0 [2]
4-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazoleIC50190.0 [1], 240.0 [2]
1-[2-(4-Benzyl-2-chloro-phenoxy)-ethyl]-pyrrolidineIC501200.0 [1], 1230.0 [2], 2000.0 [3]
3-[4-(4-Benzyl-phenoxy)-butylamino]-propionic acidIC5018.0 [1], 490.0 [2]
3-{Methyl-[3-(4-pyridin-3-ylmethyl-phenoxy)-propyl]-amino}-propionic acid methyl esterIC50300.0 [1], 820.0 [2]
{[4-(4-Benzyl-phenoxy)-butyl]-methyl-amino}-acetic acidIC50110.0 [1], 450.0 [2]
3-[2-(4-Benzyl-phenoxy)-ethylamino]-propionic acid methyl esterIC50220.0 [1], 590.0 [2]
1-(1-{2-[4-(1,3-Benzothiazol-2-yloxy)phenoxy]ethyl}piperidin-4-yl)pyrrolidin-2-oneIC509.7 [1], 16.0 [2], 365.0 [3]
N-[4-(Benzyloxy)phenyl]glycinamideIC50135.0 [1], 280.0 [2], 300.0 [3]
(R)-4-(2-((4-(4-Chlorophenoxy)phenoxy)methyl)pyrrolidin-1-yl)butanoic acidIC5033.0 [1], 68.5 [2], 70.8 [3]
2-(Methyl-{3-[methyl-(4-sulfamoyl-benzyl)-amino]-propyl}-amino)-N-(4-phenoxy-phenyl)-acetamideIC5033.0 [1], 1000.0 [2]
4-((Methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)amino)propyl)amino)methyl)benzoic acidIC506.0 [1], 120.0 [2]
4-[[[2,2-Dimethyl-3-[methyl-[2-oxo-2-(4-phenoxyanilino)ethyl]amino]propyl]-methylamino]methyl]benzoic acidIC507.0 [1], 70.0 [2]
4-((Methyl(2-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)amino)ethyl)amino)methyl)benzoic acidIC5015.0 [1], 140.0 [2]
4-[[Methyl-[3-[methyl-[2-oxo-2-(4-phenoxyanilino)ethyl]amino]propyl]amino]methyl]cyclohexane-1-carboxylic acidIC5025.0 [1], 430.0 [2]
3-{Methyl-[3-(4-thiophen-3-ylmethyl-phenoxy)-propyl]-amino}-propionic acidIC502.0 [1], 190.0 [2]
3-[Methyl[3-[4-(biphenyl-4-yloxy)phenoxy]propyl]amino]propanoic acidIC500.5 [1], 190.0 [2]
2-[4-[4-(2-Pyrrolidin-1-ylethoxy)phenoxy]phenyl]-4,5-dihydro-1,3-oxazoleIC50550.0 [1], 590.0 [2]
Sodium valproateIC5010000.0 [1]
ResveratrolIC50212000.0 [1], 366000.0 [2]
Trichostatin AIC5010000.0 [1]
VorinostatIC501670.0 [1], 7650.0 [2]
NimesulideIC50100000.0 [1]
4-(Dimethylamino)-n-[7-(hydroxyamino)-7-oxoheptyl]benzamideIC50300.0 [1], 680.0 [2]
ZileutonIC50850.0 [1], 100000.0 [2]
EntinostatIC5010000.0 [1]
PanobinostatIC5010000.0 [1]
[6]-GingerolIC5056120.0 [1], 58290.0 [2]
5-HydroxyindoleIC501000000.0 [1], 2000000.0 [2]
ShogaolIC5012540.0 [1], 24610.0 [2]
BelinostatIC5010000.0 [1]
MocetinostatIC5010000.0 [1]
TubacinIC5010000.0 [1]
ScriptaidIC504400.0 [1], 10000.0 [2]
TesmilifeneIC50160.0 [1], 400.0 [2]
RicolinostatIC5010000.0 [1]
AbexinostatIC5010000.0 [1]
QuisinostatIC5010000.0 [1]
DihydroresveratrolIC50145000.0 [1], 247000.0 [2]
PracinostatIC5010000.0 [1]
GivinostatIC5010000.0 [1]
Cudc-101IC5010000.0 [1]
5-FluoroindoleIC501000000.0 [1], 2000000.0 [2]
ResminostatIC5010000.0 [1]
5-ChloroindoleIC501000000.0 [1], 1510000.0 [2]
2-Amino-3-benzyloxypyridineIC50308000.0 [1], 619000.0 [2]
N-(Pyridin-3-ylmethyl)anilineIC501321000.0 [1], 1667000.0 [2]
N-(6-(2-Aminophenylamino)-6-oxohexyl)-4-methylbenzamideIC5010000.0 [1]
2-(1-Benzyl-5-methoxy-2-methyl-1h-indol-3-yl)acetamideIC50100000.0 [1]
7-BenzyloxytryptamineIC5012500.0 [1], 217000.0 [2]
4-(2-Amino-1,3-thiazol-4-yl)phenolIC501000000.0 [1], 1443000.0 [2]
5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-oneIC50100000.0 [1]
3-Decanone, 1-(4-hydroxy-3-methoxyphenyl)-5-methoxy-IC50100000.0 [1]
(2S,3S)-3-Amino-2-hydroxy-4-phenylbutanoic acidIC501000000.0 [1]
(S)-4-(2-((4-(4-Chlorophenoxy)phenoxy)methyl)pyrrolidin-1-yl)butanoic acidIC5037.0 [1], 47.0 [2]
5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-oneIC5015240.0 [1], 21590.0 [2]
(S)-4-Methyl-2-[[(2S,3S)-2-hydroxy-3-amino-4-phenylbutanoyl]amino]pentanoic acidIC5020000.0 [1]
1-[2-(4-Benzyl-phenoxy)-ethyl]-azepaneIC5037.0 [1], 120.0 [2]
4-Benzylphenoxy-N-ethylmorpholineIC50230.0 [1], 1320.0 [2]
3-[[(2S,3R)-2-Hydroxy-3-amino-4-phenylbutanoyl]amino]propanoic acidIC50100000.0 [1]
5-[2-(4-Benzylphenoxy)ethyl]-5H-imidazo[4,5-c]pyridineIC5011.0 [1]
N-{1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidin-4-yl}-acetamideIC5050.0 [1]
1-[2-(4-Benzylphenoxy)ethyl]pyrrolidine-3-olIC5030.0 [1]
1-[1-[2-(4-Benzylphenoxy)ethyl]-4-piperidinyl]ureaIC5087.0 [1]
5-Benzyloxytryptamine hydrochlorideIC5013000.0 [1], 100000.0 [2]
5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-oneIC50100000.0 [1]
1-(3,4-Dimethoxyphenyl)-5-hydroxydecan-3-oneIC50100000.0 [1]
3,3-Difluoro-4-oxo-6-phenyl-5-hexenoic acid ethyl esterIC505000000.0 [1]
Shogaol acetateIC509310.0 [1], 29470.0 [2]
3-(3-Amino-2-hydroxy-4-phenyl-butyrylamino)-propionic acidIC5080000.0 [1]
1-{2-[4-(4-Methoxy-benzyl)-phenoxy]-ethyl}-pyrrolidineIC5070.0 [1], 890.0 [2]
1-[3-(4-Benzyl-phenyl)-allyl]-pyrrolidineIC50260.0 [1], 320.0 [2]
1-[2-(4-Benzyl-benzenesulfinyl)-ethyl]-pyrrolidineIC509700.0 [1], 14000.0 [2]
1-[2-(4-Benzyl-phenoxy)-propyl]-pyrrolidineIC50700.0 [1], 790.0 [2]
1-[2-[4-(alpha-Hydroxybenzyl)phenoxy]ethyl]pyrrolidineIC501800.0 [1], 4600.0 [2]
1-{2-[4-(3-Chloro-benzyl)-phenoxy]-ethyl}-pyrrolidineIC5080.0 [1], 160.0 [2]
1-[2-(4-Phenethyl-phenoxy)-ethyl]-pyrrolidineIC50220.0 [1]
1-[3-(4-Benzyl-phenyl)-propyl]-pyrrolidineIC50670.0 [1], 1300.0 [2]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Leukotriene A4 hydrolase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 31 Mar. 2025, https://www.aatbio.com/data-sets/leukotriene-a4-hydrolase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, March 31). Quest Database™ Leukotriene A4 hydrolase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/leukotriene-a4-hydrolase-inhibitors-ic50-ki.
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