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Lethal(3)malignant brain tumor-like protein 4 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
(5-Bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanoneIC5010000.0 [1], 30000.0 [2], 69000.0 [3]
ChlorpheniramineIC50100000.0 [1]
OxybutyninIC50100000.0 [1]
MaprotilineIC50100000.0 [1]
BifemelaneIC50100000.0 [1]
(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)IC5010000.0 [1]
4-Methyl-N-[3-(1-pyrrolidinyl)propyl]benzenesulfonamideIC50100000.0 [1]
6-Bromo-3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-4-hydroxy-2-oxo-1H-quinazoline-4-carboxamideIC50100000.0 [1]
N,N-Dimethyl-4-(1-methyl-9H-pyrido[3,4-b]indol-4-yl)butan-1-amineIC50100000.0 [1]
1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone)IC5010000.0 [1]
1-(N-Methylamino)-4-phenylbutaneIC50100000.0 [1]
1,4-Bis(4-(pyrrolidinyl)piperidinyl)benzamideIC5010000.0 [1]
4-(2-Methoxy-4-methylphenoxy)-N-methylbutan-1-amineIC5092000.0 [1]
4-(4-Chloro-3-ethylphenoxy)-N-methylbutan-1-amineIC50100000.0 [1]
4-(4-Benzylphenoxy)-N-methylbutan-1-amineIC50100000.0 [1]
1-(1-(4-Chlorophenethyl)piperidin-4-yl)-N-methylmethanamineIC50100000.0 [1]
1-(7-Bromo-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)-3-(dimethylamino)propan-1-oneIC5012000.0 [1]
2-Isopropyl-5-(methylamino)-2-o-tolylpentanenitrileIC50100000.0 [1]
3-Chloro-N-(3-(diethylamino)propyl)-4-fluorobenzenesulfonamideIC50100000.0 [1]
2-(3-(4-Chlorophenyl)isochroman-1-yl)-N-methylethanamineIC5078000.0 [1]
3-(11h-Dibenzo[b,f][1,4]oxathiepin-11-yl)-n-methylpropan-1-amineIC50100000.0 [1]
UNC 926 hydrochlorideIC5015600.0 [1]
(3-Bromophenyl)-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC5030000.0 [1]
4-(Dimethylamino)butan-2-yl 5-(1-phenylethyl)furan-2-carboxylateIC50100000.0 [1]
[6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)furan-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)thiophen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-(Benzylamino)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Benzyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Phenoxy-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Phenyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
2-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
3-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
[3-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[2-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3,4-Bis(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonylphenyl]methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]methanoneIC508400.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-[(4-pyrrolidin-1-ylpiperidin-1-yl)methyl]phenyl]methanoneIC5010000.0 [1]
(4-Piperidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(Azepan-1-yl)piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(4-Morpholin-4-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Cyclohexylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpyrrolidin-1-ium-1-yl)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Piperidin-4-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(4-Cyclopentylpiperazine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpiperidin-4-yl)piperazine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[1-(4-Methylpiperazin-1-yl)ethyl]piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylazepan-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(3-Pyrrolidin-1-ylazetidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(3-pyrrolidin-1-ylpyrrolidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)-N-(3-pyrrolidin-1-ylpropyl)benzamideIC5010000.0 [1]
[4-(2,7-Diazaspiro[3.4]octane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,7-Diazaspiro[4.4]nonane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,8-Diazaspiro[4.5]decane-8-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-(2-Methyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-7-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylazepane-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylazepan-1-yl)methanoneIC5010000.0 [1]
[4-[4-(Azetidin-1-yl)piperidine-1-carbonyl]phenyl]-[4-(azetidin-1-yl)piperidin-1-yl]methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-2-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpyrrolidin-2-yl)piperidine-1-carbonyl]phenyl]-[4-(1-methylpyrrolidin-2-yl)piperidin-1-yl]methanoneIC5010000.0 [1]
[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanoneIC5010000.0 [1]
[6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)pyridin-3-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Nitro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Amino-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[2,3,5,6-tetrafluoro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[2,5-Dimethyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-1-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(3-Bromophenyl)-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanoneIC5030000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)benzamideIC5010000.0 [1]
[4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanoneIC5010000.0 [1]
[3-Bromo-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-(3-(Diethylamino)propyl)-2,5-dimethoxybenzenesulfonamideIC50100000.0 [1]
(3-Bromophenyl)-[4-(dimethylamino)piperidin-1-yl]methanoneIC5030000.0 [1]
(3-Bromophenyl)-(4-piperidin-1-ylpiperidin-1-yl)methanoneIC5030000.0 [1]
1-(3-Bromophenyl)sulfonyl-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]
(3-Bromophenyl)-(4-cyclopentylpiperazin-1-yl)methanoneIC5030000.0 [1]
(2-Bromophenyl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5030000.0 [1]
(4-Bromophenyl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5030000.0 [1]
Phenyl-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5030000.0 [1]
(3-Bromophenyl)-(3-pyrrolidin-1-ylpyrrolidin-1-yl)methanoneIC5030000.0 [1]
(3-Bromophenyl)-[4-(methylamino)piperidin-1-yl]methanoneIC5030000.0 [1]
3-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)benzoic acidIC5030000.0 [1]
N-Methyl-3-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC5030000.0 [1]
(3-Bromophenyl)-[4-(2-methylpyrrolidin-1-yl)piperidin-1-yl]methanoneIC5030000.0 [1]
[4-(Azetidin-1-yl)piperidin-1-yl]-(3-bromophenyl)methanoneIC5030000.0 [1]
(3-Bromophenyl)-[4-(1-methylpyrrolidin-1-ium-1-yl)piperidin-1-yl]methanoneIC5030000.0 [1]
(3-Bromophenyl)-[4-(2,5-dihydropyrrol-1-yl)piperidin-1-yl]methanoneIC5030000.0 [1]
(3-Bromophenyl)-[4-(1-methylpyrrolidin-2-yl)piperidin-1-yl]methanoneIC5030000.0 [1]
(3-Bromophenyl)-(4-pyrrolidin-1-ylazepan-1-yl)methanoneIC5030000.0 [1]
1-[(3-Bromophenyl)methyl]-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]
1-[1-(3-Bromophenyl)ethyl]-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]
1-Benzhydryl-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Lethal(3)malignant brain tumor-like protein 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/lethal-3-malignant-brain-tumor-like-protein-4-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Lethal(3)malignant brain tumor-like protein 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lethal-3-malignant-brain-tumor-like-protein-4-inhibitors-ic50-ki.
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