| (5-Bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone | IC50 | 4200.0 [1], 6000.0 [2], 7900.0 [3], 21000.0 [4] |
| (2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone) | IC50 | 2300.0 [1], 8900.0 [2] |
| 1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone) | IC50 | 10000.0 [1], 170000.0 [2] |
| UNC 926 hydrochloride | IC50 | 3900.0 [1], 4700.0 [2] |
| (3-Bromophenyl)-(4-pyrrolidin-2-ylpiperidin-1-yl)methanone | IC50 | 30000.0 [1] |
| (3-Bromophenyl)-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanone | IC50 | 20600.0 [1], 23600.0 [2] |
| Chlorpheniramine | IC50 | 41000.0 [1] |
| Oxybutynin | IC50 | 100000.0 [1] |
| Maprotiline | IC50 | 61000.0 [1] |
| Bifemelane | IC50 | 91000.0 [1] |
| I-OMe-Tyrphostin AG 538 | IC50 | 282.0 [1] |
| Cefsulodin sodium salt | IC50 | 98.0 [1] |
| 4-Methyl-N-[3-(1-pyrrolidinyl)propyl]benzenesulfonamide | IC50 | 17000.0 [1] |
| 6-Bromo-3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-4-hydroxy-2-oxo-1H-quinazoline-4-carboxamide | IC50 | 52000.0 [1] |
| N,N-Dimethyl-4-(1-methyl-9H-pyrido[3,4-b]indol-4-yl)butan-1-amine | IC50 | 21000.0 [1] |
| 1-(N-Methylamino)-4-phenylbutane | IC50 | 68000.0 [1] |
| 1,4-Bis(4-(pyrrolidinyl)piperidinyl)benzamide | IC50 | 2900.0 [1] |
| 4-(2-Methoxy-4-methylphenoxy)-N-methylbutan-1-amine | IC50 | 100000.0 [1] |
| 4-(4-Chloro-3-ethylphenoxy)-N-methylbutan-1-amine | IC50 | 96000.0 [1] |
| 4-(4-Benzylphenoxy)-N-methylbutan-1-amine | IC50 | 91000.0 [1] |
| 1-(1-(4-Chlorophenethyl)piperidin-4-yl)-N-methylmethanamine | IC50 | 69000.0 [1] |
| 1-(7-Bromo-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)-3-(dimethylamino)propan-1-one | IC50 | 100000.0 [1] |
| 2-Isopropyl-5-(methylamino)-2-o-tolylpentanenitrile | IC50 | 18000.0 [1] |
| 3-Chloro-N-(3-(diethylamino)propyl)-4-fluorobenzenesulfonamide | IC50 | 100000.0 [1] |
| 5-Bromo-N-(5-(pyrrolidin-1-YL)pentyl)nicotinamide | IC50 | 46000.0 [1] |
| 2-(3-(4-Chlorophenyl)isochroman-1-yl)-N-methylethanamine | IC50 | 100000.0 [1] |
| 3-(11h-Dibenzo[b,f][1,4]oxathiepin-11-yl)-n-methylpropan-1-amine | IC50 | 14000.0 [1] |
| 1-Phenyl-4-pyrrolidin-1-ylpiperidine | IC50 | 90000.0 [1] |
| 4-(Dimethylamino)butan-2-yl 5-(1-phenylethyl)furan-2-carboxylate | IC50 | 84000.0 [1] |
| 4-(Pyrrolidin-1-Yl)-1-{4-[2-(Pyrrolidin-1-Yl)ethyl]phenyl}piperidine | IC50 | 14000.0 [1] |
| [6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 5000.0 [1] |
| [5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)furan-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 2300.0 [1] |
| [5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)thiophen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 3700.0 [1] |
| [3-(Benzylamino)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 740.0 [1] |
| [3-Benzyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 1700.0 [1] |
| [3-Phenoxy-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 3000.0 [1] |
| [3-Phenyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 2000.0 [1] |
| N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamide | IC50 | 4000.0 [1] |
| 2-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamide | IC50 | 6600.0 [1] |
| 3-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamide | IC50 | 9600.0 [1] |
| 3-Bromo-N-(2-ethyl-1,3-dihydroisoindol-5-yl)benzamide | IC50 | 30000.0 [1] |
| N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamide | IC50 | 10000.0 [1] |
| [3-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 2800.0 [1] |
| [2-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 3000.0 [1] |
| [3,4-Bis(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 2200.0 [1] |
| (4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonylphenyl]methanone | IC50 | 3300.0 [1] |
| (4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]methanone | IC50 | 1500.0 [1] |
| (4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-[(4-pyrrolidin-1-ylpiperidin-1-yl)methyl]phenyl]methanone | IC50 | 3800.0 [1] |
| (4-Piperidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanone | IC50 | 6800.0 [1] |
| [4-(Azepan-1-yl)piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanone | IC50 | 4200.0 [1] |
| [4-(4-Morpholin-4-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 7100.0 [1] |
| (4-Cyclohexylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanone | IC50 | 10000.0 [1] |
| [4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 7200.0 [1] |
| [4-[4-(1-Methylpyrrolidin-1-ium-1-yl)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 7500.0 [1] |
| [4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanone | IC50 | 5200.0 [1] |
| (4-Piperidin-4-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanone | IC50 | 3500.0 [1] |
| [4-(4-Cyclopentylpiperazine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 7600.0 [1] |
| [4-[4-(1-Methylpiperidin-4-yl)piperazine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 3300.0 [1] |
| [4-[1-(4-Methylpiperazin-1-yl)ethyl]piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanone | IC50 | 4400.0 [1] |
| (4-Pyrrolidin-1-ylazepan-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanone | IC50 | 5900.0 [1] |
| [4-(3-Pyrrolidin-1-ylazetidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 9500.0 [1] |
| (4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(3-pyrrolidin-1-ylpyrrolidine-1-carbonyl)phenyl]methanone | IC50 | 6500.0 [1] |
| 4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)-N-(3-pyrrolidin-1-ylpropyl)benzamide | IC50 | 5500.0 [1] |
| [4-(2,7-Diazaspiro[3.4]octane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 5600.0 [1] |
| [4-(2,7-Diazaspiro[4.4]nonane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 7100.0 [1] |
| [4-(2,8-Diazaspiro[4.5]decane-8-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 5000.0 [1] |
| [4-(2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 6900.0 [1] |
| N-(2-Methyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-7-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamide | IC50 | 8400.0 [1] |
| [4-(4-Pyrrolidin-1-ylazepane-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylazepan-1-yl)methanone | IC50 | 8100.0 [1] |
| [4-[4-(Azetidin-1-yl)piperidine-1-carbonyl]phenyl]-[4-(azetidin-1-yl)piperidin-1-yl]methanone | IC50 | 7400.0 [1] |
| [4-(4-Pyrrolidin-2-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanone | IC50 | 10000.0 [1] |
| [4-[4-(1-Methylpyrrolidin-2-yl)piperidine-1-carbonyl]phenyl]-[4-(1-methylpyrrolidin-2-yl)piperidin-1-yl]methanone | IC50 | 10000.0 [1] |
| [4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone | IC50 | 10000.0 [1] |
| [6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)pyridin-3-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 4500.0 [1] |
| [3-Nitro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 2700.0 [1] |
| [3-Amino-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 6800.0 [1] |
| (4-Pyrrolidin-1-ylpiperidin-1-yl)-[2,3,5,6-tetrafluoro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanone | IC50 | 2900.0 [1] |
| [2,5-Dimethyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 1200.0 [1] |
| [4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-1-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 3100.0 [1] |
| N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)benzamide | IC50 | 6800.0 [1] |
| [4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 6600.0 [1] |
| [4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanone | IC50 | 10700.0 [1] |
| [3-Bromo-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | IC50 | 2500.0 [1] |
| 7-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]-1,4-dioxa-7-azaspiro[4.4]nonane | IC50 | 92000.0 [1] |
| 6-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]-2-oxa-6-azaspiro[3.3]heptane | IC50 | 65000.0 [1] |
| 1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]pyrrolidine-3-carbonitrile | IC50 | 128000.0 [1] |
| 1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]azepane | IC50 | 63000.0 [1] |
| 1-[3-Chloro-4-(2-pyrrolidin-1-ylethyl)phenyl]-4-pyrrolidin-1-ylpiperidine | IC50 | 21000.0 [1] |
| 4-Piperidin-1-yl-1-[4-(2-pyrrolidin-1-ylethyl)phenyl]piperidine | IC50 | 50000.0 [1] |
| 4-Pyrrolidin-1-yl-1-[4-(3-pyrrolidin-1-ylpropyl)phenyl]piperidine | IC50 | 10000.0 [1] |
| 4-Pyrrolidin-1-yl-1-[3-(2-pyrrolidin-1-ylethyl)phenyl]piperidine | IC50 | 30000.0 [1] |
| [3-(Hydroxymethyl)-1-[2-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]azetidin-3-yl]methanol | IC50 | 60000.0 [1] |
| 4-Pyrrolidin-1-yl-1-[4-(pyrrolidin-1-ylmethyl)phenyl]piperidine | IC50 | 57000.0 [1] |
| 1-[[4-(2-Pyrrolidin-1-ylethyl)phenyl]methyl]pyrrolidine | IC50 | 51000.0 [1] |
| 4-Pyrrolidin-1-yl-1-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]piperidine | IC50 | 32000.0 [1] |
| 4-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]morpholine | IC50 | 125000.0 [1] |
| 1-[4-[2-(Azetidin-1-yl)ethyl]phenyl]-4-pyrrolidin-1-ylpiperidine | IC50 | 86000.0 [1] |
| 1-[4-[2-(3,3-Difluoroazetidin-1-yl)ethyl]phenyl]-4-pyrrolidin-1-ylpiperidine | IC50 | 152000.0 [1] |
| 1-[4-(2-Piperidin-1-ylethyl)phenyl]-4-pyrrolidin-1-ylpiperidine | IC50 | 50000.0 [1] |
| 4-Pyrrolidin-1-yl-1-[3-(pyrrolidin-1-ylmethyl)phenyl]piperidine | IC50 | 45000.0 [1] |