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L-lactate dehydrogenase B chain Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Oxamic acidIC5033800.0 [1]
Oxamic acidKi94400.0 [1]
7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-naphthalene-1-carboxylic AcidKi50.0 [1], 1000.0 [2]
2,3-Dihydroxy-4-isopropyl-6-methyl-naphthalene-1-carboxylic acidKi3000.0 [1], 91000.0 [2], 92000.0 [3]
2,3-Dihydroxy-6,7-dimethyl-4-propyl-1-naphthoic acidKi100.0 [1], 19000.0 [2]
2,3-Dihydroxy-6-methyl-4-propyl-naphthalene-1-carboxylic AcidKi1000.0 [1], 49000.0 [2]
2,3-Dihydroxy-4-isopropyl-6-methyl-7-benzylnaphthalene-1-carboxylic acidKi200.0 [1], 7000.0 [2]
2,3-Dihydroxy-4,6-dimethyl-naphthalene-1-carboxylic AcidKi34000.0 [1], 250000.0 [2]
2,3-Dihydroxy-4,6,7-trimethyl-naphthalene-1-carboxylic AcidKi4000.0 [1], 190000.0 [2]
2,3-Dihydroxy-4-isopropyl-6,7-dimethylnaphthalene-1-carboxylic acidKi2000.0 [1], 78000.0 [2]
7-Benzyl-2,3-dihydroxy-4,6-dimethyl-naphthalene-1-carboxylic AcidKi500.0 [1], 39000.0 [2]
3-[[3-(Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino]-5-(3,5-difluorophenoxy)benzoic acidIC5043.0 [1], 1150.0 [2]
2',6'-Dichloro-4-((2-chlorophenyl)thio)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-oneIC506900.0 [1], 24000.0 [2]
2,3-Dihydroxy-4-isopropyl-6-methyl-7-[4-(trifluoromethyl)benzyl]naphthalene-1-carboxylic acidKi13000.0 [1], 81000.0 [2]
3,8,9,10-Tetrahydroxy-5H-benzo[h]chromene-2,6-dioneKi15100.0 [1], 23200.0 [2]
GossypolKi1400.0 [1]
Gossylic iminolactoneKi92000.0 [1]
Gossylic nitrile-1,1'-diacetateKi33000.0 [1]
Gossylic lactoneKi400.0 [1]
(2R)-5-(2-Chlorophenyl)sulfanyl-4-hydroxy-2-(4-morpholin-4-ylphenyl)-2-thiophen-3-yl-1,3-dihydropyridin-6-oneIC50441.0 [1]
4-((2-Chlorophenyl)thio)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-oneIC5019000.0 [1]
CID 135411083IC5056400.0 [1]
2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)propanamideIC503000.0 [1]
[8-Cyano-2-(8-cyano-6,7-dihydroxy-3-methyl-1-pentanoyloxy-5-propan-2-ylnaphthalen-2-yl)-6,7-dihydroxy-3-methyl-5-propan-2-ylnaphthalen-1-yl] pentanoateKi39000.0 [1]
Ldh-IN-1IC5027.0 [1]
2-[[5-Cyano-4-(3-methoxyphenyl)-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)butanamideIC507700.0 [1]
2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)acetamideIC5011100.0 [1]
2-[[5-Cyano-4-(3,4-dichlorophenyl)-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)propanamideIC503700.0 [1]
2-[[4-(4-Chloro-3-fluorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)propanamideIC502300.0 [1]
4-Hydroxy-1,2,5-thiadiazole-3-carboxylic acidIC507800.0 [1]
CID 56844254IC509200.0 [1]
5-Hydroxy-4-((2-nitrophenyl)thio)-1,6-dihydro-[1,1'-biphenyl]-3(2H)-oneIC5012300.0 [1]
2-(2-Hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylbenzonitrileIC5011000.0 [1]
5-(2-Chlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC5013000.0 [1]
5-(3-Chlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC5027000.0 [1]
5-(4-Chlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC5037000.0 [1]
2-(2-Chlorophenyl)sulfanyl-3-hydroxy-5-(4-methoxyphenyl)cyclohex-2-en-1-oneIC506900.0 [1]
5-(2-Chloro-6-fluorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC505300.0 [1]
5-(2-Bromo-6-chlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC503400.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-[2-chloro-6-(trifluoromethyl)phenyl]-3-hydroxycyclohex-2-en-1-oneIC5050000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-difluorophenyl)-3-hydroxycyclohex-2-en-1-oneIC501300.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dibromophenyl)-3-hydroxycyclohex-2-en-1-oneIC5015000.0 [1]
2-(2-Chlorophenyl)sulfanyl-5-(2,6-dimethylphenyl)-3-hydroxycyclohex-2-en-1-oneIC501900.0 [1]
5-(3-Bromo-2,6-dichlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC5010000.0 [1]
5-[2,6-Bis(trifluoromethyl)phenyl]-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-oneIC507400.0 [1]
2-[4-(2-Chlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrileIC506600.0 [1]
2-[4-(3-Chlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrileIC5010000.0 [1]
2-[4-(4-Chlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrileIC5010000.0 [1]
2-[4-(2,6-Dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrileIC504900.0 [1]
2-[4-(2-Bromo-6-chlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrileIC502000.0 [1]
2-[4-[2-Chloro-6-(trifluoromethyl)phenyl]-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrileIC502800.0 [1]
2-[4-(2,6-Dimethylphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrileIC507800.0 [1]
2-[4-(2,6-Dibromophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrileIC50860.0 [1]
2-[5-(3,4-Difluorophenyl)-3-oxo-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acidIC50724.0 [1]
2-[3-Phenyl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC50204.0 [1]
2-[3-(3-Phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5049.0 [1]
2-[3-Phenyl-4-(4-sulfamoylanilino)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5096.0 [1]
2-[3-(3-Phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]-5-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5062.0 [1]
2-[3-Phenyl-5-pyridin-4-yl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC502820.0 [1]
2-[5-[3-(2-Fluorophenyl)phenyl]-3-oxo-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acidIC50911.0 [1]
2-[5-Cyclopropyl-3-(3-phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5020.0 [1]
2-[5-Amino-3-(3-phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5075.0 [1]
2-[3-(3,4-Difluorophenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC50129.0 [1]
2-[3-Oxo-5-(3-phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acidIC50424.0 [1]
2-[5-Cyclopropyl-3-phenyl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5020.0 [1]
2-[3-(3-Phenylphenyl)-4-(4-sulfamoylanilino)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5078.0 [1]
2-[5-(3-Bromophenyl)-3-oxo-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acidIC501510.0 [1]
2-[3-Phenyl-5-pyridin-3-yl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC50259.0 [1]
2-[5-(Cyclopropylmethyl)-3-phenyl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC508.0 [1]
2-[5-Cyclopropyl-3-(3-phenylphenyl)-4-(4-sulfamoylphenoxy)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC50119.0 [1]
2-(2-Chloro-5-hydroxyphenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-oneIC50180.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-oneIC50410.0 [1]
2-[4-(2,6-Dichloro-3-propan-2-yloxyphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanyl-4-hydroxybenzonitrileIC50140.0 [1]
2-[4-(2,6-Dichloro-3-propan-2-yloxyphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanyl-4-methoxybenzonitrileIC502400.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-oneIC50230.0 [1]
Ethyl 2-[4-chloro-3-[4-(2,6-dichloro-3-phenylphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetateIC50120.0 [1]
2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-[2,6-dichloro-3-(oxan-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-oneIC50490.0 [1]
7-(8-Carboxy-6,7-dihydroxy-5-propan-2-ylnaphthalen-2-yl)-2,3-dihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carboxylic acidKi700.0 [1]
2,3-Dihydroxy-6-methyl-7-(2-methylphenyl)-4-propan-2-ylnaphthalene-1-carboxylic acidKi125000.0 [1]
2,3-Dihydroxy-6-methyl-7-(3-methylphenyl)-4-propan-2-ylnaphthalene-1-carboxylic acidKi34000.0 [1]
2,3-Dihydroxy-6-methyl-7-(4-methylphenyl)-4-propan-2-ylnaphthalene-1-carboxylic acidKi8000.0 [1]
2-[(5-Cyano-6-oxo-4-phenyl-1H-pyrimidin-2-yl)sulfanyl]-N-(4-sulfamoylphenyl)acetamideIC5042800.0 [1]
N-(4-Chlorophenyl)-2-[[4-(4-chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]acetamideIC50100000.0 [1]
N-(3-Chloro-2-methylphenyl)-2-[[4-(4-chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]acetamideIC50100000.0 [1]
N-(3-Chloro-4-fluorophenyl)-2-[[4-(4-chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]acetamideIC50100000.0 [1]
N-(3-Chloro-4-methoxyphenyl)-2-[[4-(4-chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]acetamideIC50100000.0 [1]
2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(3,4-dimethylphenyl)acetamideIC50100000.0 [1]
N-(3-Chlorophenyl)-2-[[4-(4-chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]acetamideIC50100000.0 [1]
2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-propan-2-ylphenyl)acetamideIC5098000.0 [1]
N-(3-Chloro-4-methylphenyl)-2-[[4-(4-chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]acetamideIC5093000.0 [1]
2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-[4-(methylsulfamoyl)phenyl]acetamideIC50100000.0 [1]
2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)butanamideIC502400.0 [1]
[[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(5-carbamoyl-3,4-dihydro-2H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphateIC509400.0 [1]
7-[(4-Chlorophenyl)methyl]-2,3-dihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carboxylic acidKi8000.0 [1]
3-Cyclopentyl-5-[[3-(cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino]benzoic acidIC50220.0 [1]
3-(5-Amino-6-{[(1r)-1-Phenylethyl]amino}pyrazin-2-Yl)-4-Chlorobenzoic AcidIC508000.0 [1]
3-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzoic acidIC5012000.0 [1]
3-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzamideIC5092000.0 [1]
3-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]-N-methylsulfonylbenzamideIC50100000.0 [1]
4-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]pyridine-2-carboxylic acidIC5048000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ L-lactate dehydrogenase B chain Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/l-lactate-dehydrogenase-b-chain-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ L-lactate dehydrogenase B chain Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/l-lactate-dehydrogenase-b-chain-inhibitors-ic50-ki.
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