| (3S)-3-Amino-1-hydroxy-1,2,3,4-tetrahydroquinolin-2-one | IC50 | 23.0 [1] |
| (3S)-3-Amino-1-hydroxy-1,2,3,4-tetrahydroquinolin-2-one | Ki | 14.0 [1] |
| (5S)-5-Amino-7-hydroxy-2-phenyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 24.3 [1] |
| (5S)-5-Amino-7-hydroxy-2-phenyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | Ki | 1.9 [1] |
| (5S)-5-Amino-7-hydroxy-3-[(3-methoxyphenyl)methyl]-1-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 65.6 [1] |
| (5S)-5-Amino-7-hydroxy-3-[(3-methoxyphenyl)methyl]-1-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | Ki | 22.0 [1] |
| (5S)-5-Amino-2-benzyl-7-hydroxy-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 59.4 [1] |
| (5S)-5-Amino-2-benzyl-7-hydroxy-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | Ki | 23.0 [1] |
| (6S)-6-Amino-1-benzyl-4-hydroxy-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | IC50 | 22.5 [1] |
| (6S)-6-Amino-1-benzyl-4-hydroxy-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | Ki | 12.0 [1] |
| (6S)-6-Amino-1-benzyl-4-hydroxy-3-(trifluoromethyl)-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | IC50 | 42.7 [1], 43.7 [2] |
| (6S)-6-Amino-1-benzyl-4-hydroxy-3-(trifluoromethyl)-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | Ki | 48.0 [1] |
| (3S)-3-Amino-1-hydroxy-7-methoxy-3,4-dihydroquinolin-2-one | IC50 | 22.0 [1] |
| (5S)-5-Amino-7-hydroxy-1-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 329.0 [1] |
| (5S)-5-Amino-3-benzyl-7-hydroxy-1-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 63.7 [1] |
| (5S)-5-Amino-3-benzyl-7-hydroxy-1-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | Ki | 32.0 [1] |
| (6S)-6-Amino-4-hydroxy-2-phenyl-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | IC50 | 85.0 [1] |
| (6S)-6-Amino-4-hydroxy-2-phenyl-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | Ki | 41.0 [1] |
| (5S)-5-Amino-7-hydroxy-3-[(4-methoxyphenyl)methyl]-1-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 440.0 [1] |
| (5S)-5-Amino-7-hydroxy-2-[(4-methoxyphenyl)methyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 28.3 [1] |
| (6S)-6-Amino-2-benzyl-4-hydroxy-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | IC50 | 182.0 [1] |
| (5S)-5-Amino-3-benzyl-2-ethyl-7-hydroxy-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 24.3 [1] |
| (5S)-5-Amino-7-hydroxy-2-[2-(trifluoromethyl)phenyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 38.8 [1] |
| (5S)-5-Amino-7-hydroxy-2-[4-(trifluoromethyl)phenyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 31.6 [1] |
| (5S)-5-Amino-7-hydroxy-2-methyl-3-[[4-(trifluoromethyl)phenyl]methyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 37.0 [1] |
| (5S)-5-Amino-2-benzyl-7-hydroxy-3-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 81.6 [1] |
| (5S)-5-Amino-7-hydroxy-2-[(3-methoxyphenyl)methyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 8.93 [1] |
| (5S)-5-Amino-7-hydroxy-2-[(2-methoxyphenyl)methyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 50.2 [1] |
| (5S)-5-Amino-7-hydroxy-2-(naphthalen-2-ylmethyl)-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 117.0 [1] |
| (5S)-5-Amino-7-hydroxy-2-(naphthalen-1-ylmethyl)-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 36.0 [1] |
| (5S)-5-Amino-2-cyclobutyl-7-hydroxy-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 81.3 [1] |
| (5S)-5-Amino-7-hydroxy-2-propan-2-yl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 153.0 [1] |
| (6S)-6-Amino-4-hydroxy-3-methyl-2-phenyl-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | IC50 | 2010.0 [1] |
| (5S)-5-Amino-3-benzyl-7-hydroxy-2-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 11.5 [1] |
| (5S)-5-Amino-7-hydroxy-2-methyl-3-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 42.2 [1] |
| (5S)-5-Amino-7-hydroxy-2-methyl-3-[[2-(trifluoromethyl)phenyl]methyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 40.7 [1] |
| (5S)-5-Amino-3-benzyl-7-hydroxy-2-propan-2-yl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 63.0 [1] |
| (5S)-5-Amino-7-hydroxy-2-[3-(trifluoromethyl)phenyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 74.7 [1] |
| (5S)-5-Amino-7-hydroxy-2-[[4-(trifluoromethoxy)phenyl]methyl]-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 43.6 [1] |
| (2S)-6-(4-Aminopiperazin-1-yl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid | IC50 | 1000.0 [1] |
| (3S)-3-Amino-1-hydroxy-6-phenoxy-3,4-dihydroquinolin-2-one | IC50 | 23.0 [1] |
| (3S)-3-Amino-3,4-dihydro-1H-quinolin-2-one | IC50 | 10000.0 [1] |
| 3-Amino-1-hydroxy-3-methyl-4H-quinolin-2-one | IC50 | 10000.0 [1] |
| (3S,4S)-3-Amino-1-hydroxy-4-methyl-3,4-dihydroquinolin-2-one | IC50 | 3280.0 [1] |
| (3S)-3-Amino-1-methoxy-3,4-dihydroquinolin-2-one | IC50 | 10000.0 [1] |
| (3S)-3-Amino-7-chloro-1-hydroxy-3,4-dihydroquinolin-2-one | IC50 | 29.0 [1] |
| (2R)-6-(4-Aminopiperazin-1-yl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid | IC50 | 1500.0 [1] |
| (3S)-3-Amino-1-hydroxy-6-(trifluoromethyl)-3,4-dihydroquinolin-2-one | IC50 | 29.0 [1] |
| (3S)-3-Amino-1-hydroxy-8-(trifluoromethyl)-3,4-dihydroquinolin-2-one | IC50 | 174.0 [1] |
| (3S)-1-Hydroxy-3-amino-5-methyl-3,4-dihydroquinoline-2(1H)-one | IC50 | 319.0 [1] |
| (3S)-3-Amino-5-fluoro-1-hydroxy-3,4-dihydroquinolin-2-one | IC50 | 45.0 [1] |
| (3S)-3-Amino-1-hydroxy-6-methyl-3,4-dihydroquinolin-2-one | IC50 | 30.0 [1] |
| (3S)-3-Amino-6-chloro-1-hydroxy-3,4-dihydroquinolin-2-one | IC50 | 36.0 [1] |
| (3S)-3-Amino-1-hydroxy-7-methyl-3,4-dihydroquinolin-2-one | IC50 | 37.0 [1] |
| (3S)-3-Amino-1-hydroxy-8-methoxy-3,4-dihydroquinolin-2-one | IC50 | 572.0 [1] |
| (3S)-3-Amino-1-hydroxy-8-methyl-3,4-dihydroquinolin-2-one | IC50 | 1050.0 [1] |
| (3S)-3-Amino-8-chloro-1-hydroxy-3,4-dihydroquinolin-2-one | IC50 | 252.0 [1] |
| (3S)-3-Amino-6-benzyl-1-hydroxy-7-methoxy-3,4-dihydroquinolin-2-one | Ki | 1.6 [1] |
| (3S)-3-Amino-8-fluoro-1-hydroxy-3,4-dihydroquinolin-2-one | IC50 | 40.0 [1] |
| (3S)-3-Amino-1-hydroxy-5-methoxy-3,4-dihydroquinolin-2-one | IC50 | 179.0 [1] |
| (3S)-3-Amino-5-chloro-1-hydroxy-3,4-dihydroquinolin-2-one | IC50 | 349.0 [1] |
| (3R)-3-Amino-1-hydroxy-3,4-dihydroquinolin-2-one | IC50 | 219.0 [1] |
| (3S)-3-Amino-1-hydroxy-5-(trifluoromethyl)-3,4-dihydroquinolin-2-one | IC50 | 10000.0 [1] |
| (3S)-3-Amino-1-hydroxy-7-methoxy-6-phenoxy-3,4-dihydroquinolin-2-one | IC50 | 37.0 [1] |
| 6-Amino-4-hydroxy-2-phenyl-6,7-dihydropyrazolo[4,3-b]pyridin-5-one | IC50 | 85.0 [1] |
| (5R)-5-Amino-3-benzyl-7-hydroxy-2-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one | IC50 | 63.7 [1] |