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Kir3.1/Kir3.2 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
1-(5-Cyclopropyl-2-phenylpyrazol-3-yl)-3-(4-methoxyphenyl)ureaIC502000.0 [1]
1-(4-Bromophenyl)-3-(5-cyclopentyl-2-phenylpyrazol-3-yl)ureaIC505000.0 [1]
1-(5-Cyclopentyl-2-phenylpyrazol-3-yl)-3-(3-fluorophenyl)ureaIC503600.0 [1]
1-(5-Cyclopentyl-2-phenylpyrazol-3-yl)-3-(4-methoxyphenyl)ureaIC504000.0 [1]
1-(5-Cyclopentyl-2-phenylpyrazol-3-yl)-3-(4-methylphenyl)ureaIC505000.0 [1]
1-(4-Chlorophenyl)-3-(5-cyclopentyl-2-phenylpyrazol-3-yl)ureaIC507000.0 [1]
1-[5-(2,2-Difluorocyclopropyl)-2-phenylpyrazol-3-yl]-3-(4-methylphenyl)ureaIC501600.0 [1]
1-[5-(2,2-Difluorocyclopropyl)-2-phenylpyrazol-3-yl]-3-(4-methoxyphenyl)ureaIC502400.0 [1]
1-[5-(2,2-Difluorocyclopropyl)-2-phenylpyrazol-3-yl]-3-(4-fluoro-3-methylphenyl)ureaIC50830.0 [1]
1-[5-(2,2-Difluorocyclopropyl)-2-phenylpyrazol-3-yl]-3-[4-(trifluoromethyl)phenyl]ureaIC501100.0 [1]
1-(5-Cyclopropyl-2-phenylpyrazol-3-yl)-3-(4-methylphenyl)ureaIC502000.0 [1]
1-(4-Fluoro-3-methylphenyl)-3-[2-phenyl-5-[1-(trifluoromethyl)cyclopropyl]pyrazol-3-yl]ureaIC50480.0 [1]
1-(2-Chlorophenyl)-3-[2-phenyl-5-[1-(trifluoromethyl)cyclopropyl]pyrazol-3-yl]ureaIC503700.0 [1]
1-(2-Bromophenyl)-3-[2-phenyl-5-[1-(trifluoromethyl)cyclopropyl]pyrazol-3-yl]ureaIC503800.0 [1]
1-(3,5-Dichlorophenyl)-3-[2-phenyl-5-[1-(trifluoromethyl)cyclopropyl]pyrazol-3-yl]ureaIC504000.0 [1]
1-[2-Phenyl-5-[1-(trifluoromethyl)cyclopropyl]pyrazol-3-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC506000.0 [1]
1-[2-Phenyl-5-[1-(trifluoromethyl)cyclopropyl]pyrazol-3-yl]-3-[2-(trifluoromethyl)phenyl]ureaIC506900.0 [1]
1-(3-Bromophenyl)-3-[2-phenyl-5-[1-(trifluoromethyl)cyclopropyl]pyrazol-3-yl]ureaIC508900.0 [1]
1-(2-Methoxyphenyl)-3-[2-phenyl-5-[1-(trifluoromethyl)cyclopropyl]pyrazol-3-yl]ureaIC509600.0 [1]
1-(3,4-Difluorophenyl)-3-[5-(1-methylcyclopropyl)-2-phenylpyrazol-3-yl]ureaIC50740.0 [1]
1-(4-Fluoro-3-methylphenyl)-3-[5-(1-methylcyclopropyl)-2-phenylpyrazol-3-yl]ureaIC501000.0 [1]
1-(3-Fluorophenyl)-3-[5-(1-methylcyclopropyl)-2-phenylpyrazol-3-yl]ureaIC501700.0 [1]
1-[5-(1-Methylcyclopropyl)-2-phenylpyrazol-3-yl]-3-(4-methylphenyl)ureaIC501800.0 [1]
1-[5-(1-Methylcyclopropyl)-2-phenylpyrazol-3-yl]-3-(3-methylphenyl)ureaIC501900.0 [1]
1-[5-(1-Methylcyclopropyl)-2-phenylpyrazol-3-yl]-3-[4-(trifluoromethyl)phenyl]ureaIC506200.0 [1]
1-(4-Bromophenyl)-3-[5-(1-methylcyclopropyl)-2-phenylpyrazol-3-yl]ureaIC502000.0 [1]
1-[5-(Cyclopropylmethyl)-2-phenylpyrazol-3-yl]-3-(3-fluorophenyl)ureaIC50450.0 [1]
1-(3-Chlorophenyl)-3-(5-cyclobutyl-2-phenylpyrazol-3-yl)ureaIC501400.0 [1]
1-(3-Chloro-4-fluorophenyl)-3-[5-(cyclopropylmethyl)-2-phenylpyrazol-3-yl]ureaIC50810.0 [1]
1-(5-Cyclobutyl-2-phenylpyrazol-3-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC501300.0 [1]
1-(3-Bromophenyl)-3-(5-cyclobutyl-2-phenylpyrazol-3-yl)ureaIC501900.0 [1]
1-(3-Chlorophenyl)-3-[5-(cyclopropylmethyl)-2-phenylpyrazol-3-yl]ureaIC50630.0 [1]
1-[5-(Cyclopropylmethyl)-2-phenylpyrazol-3-yl]-3-(3-methylphenyl)ureaIC50520.0 [1]
1-(5-Cyclobutyl-2-phenylpyrazol-3-yl)-3-(3,4-difluorophenyl)ureaIC5030000.0 [1]
1-[5-(Cyclopropylmethyl)-2-phenylpyrazol-3-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC50540.0 [1]
1-(3-Chloro-4-fluorophenyl)-3-(5-cyclobutyl-2-phenylpyrazol-3-yl)ureaIC501900.0 [1]
1-[5-(Cyclopropylmethyl)-2-phenylpyrazol-3-yl]-3-(3,4-difluorophenyl)ureaIC50650.0 [1]
1-[5-(Cyclopropylmethyl)-2-phenylpyrazol-3-yl]-3-(4-fluorophenyl)ureaIC50640.0 [1]
1-(3,4-Difluorophenyl)-3-(2,5-diphenylpyrazol-3-yl)ureaIC5030000.0 [1]
1-(3,4-Difluorophenyl)-3-(2-phenyl-5-propan-2-ylpyrazol-3-yl)ureaIC502000.0 [1]
1-(5-Cyclopentyl-2-phenylpyrazol-3-yl)-3-(3,4-difluorophenyl)ureaIC505100.0 [1]
1-(3,4-Difluorophenyl)-3-[2-phenyl-5-(trifluoromethyl)pyrazol-3-yl]ureaIC5030000.0 [1]
1-(5-Cyclopropyl-2-phenylpyrazol-3-yl)-3-(3-methylphenyl)ureaIC50850.0 [1]
1-(5-Cyclopropyl-2-phenylpyrazol-3-yl)-3-(3-fluorophenyl)ureaIC501200.0 [1]
1-(5-Cyclopropyl-2-phenylpyrazol-3-yl)-3-(3-methylsulfanylphenyl)ureaIC50950.0 [1]
1-(2-Phenyl-5-propan-2-ylpyrazol-3-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC502100.0 [1]
1-(3-Fluorophenyl)-3-(2-phenyl-5-propan-2-ylpyrazol-3-yl)ureaIC502100.0 [1]
1-(3-Methylphenyl)-3-(2-phenyl-5-propan-2-ylpyrazol-3-yl)ureaIC502600.0 [1]
1-(4-Methylphenyl)-3-(2-phenyl-5-propan-2-ylpyrazol-3-yl)ureaIC503900.0 [1]
Items per page: 1 - 10 of 49
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References

This online tool may be cited as follows

MLA

"Quest Database™ Kir3.1/Kir3.2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/kir3-1-kir3-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Kir3.1/Kir3.2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/kir3-1-kir3-2-inhibitors-ic50-ki.
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