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Kinesin-like protein KIFC1 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
MonastrolIC50100000.0 [1]
IspinesibIC50100000.0 [1]
5-Methyl-N-[(2R)-1-oxo-1-[[(3R)-pyrrolidin-3-yl]amino]-3-[6-[3-(trifluoromethoxy)phenyl]pyridin-3-yl]propan-2-yl]-4-propylthiophene-2-carboxamideIC50310.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-2-phenylmethoxybenzamideIC5018400.0 [1]
(2R)-2-[(2-Phenylmethoxybenzoyl)amino]-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propanoic acidIC5014500.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-3-(4-imidazo[1,2-a]pyridin-2-ylphenyl)-1-oxopropan-2-yl]-2-phenylmethoxybenzamideIC50100000.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-3-[4-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-1-oxopropan-2-yl]-2-phenylmethoxybenzamideIC50100000.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-3-[4-(1-methylimidazol-2-yl)phenyl]-1-oxopropan-2-yl]-2-phenylmethoxybenzamideIC50100000.0 [1]
3-Chloro-N-[1-[2-(dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-4-propan-2-yloxybenzamideIC5037000.0 [1]
N-[1-[[2-(Dimethylamino)acetyl]amino]-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-2-phenylmethoxybenzamideIC50100000.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-4-methoxy-3-(methoxymethyl)benzamideIC501900.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-3-ethoxy-4-methoxybenzamideIC501300.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-3,5-diethoxybenzamideIC502100.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-3-ethoxybenzamideIC503200.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-5-methyl-4-propylthiophene-2-carboxamideIC50180.0 [1]
2-Cyclopropyl-N-[1-[2-(dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-5-methylfuran-3-carboxamideIC50320.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-4-methyl-3-[(E)-prop-1-enyl]benzamideIC50140.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-4-methyl-3-propylbenzamideIC50250.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethoxy)phenyl]phenyl]propan-2-yl]-4-methoxy-3-(methoxymethyl)benzamideIC50960.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-3-[4-(3-ethylphenyl)phenyl]-1-oxopropan-2-yl]-4-methoxy-3-(methoxymethyl)benzamideIC506000.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-(3-propan-2-ylphenyl)phenyl]propan-2-yl]-4-methoxy-3-(methoxymethyl)benzamideIC5041000.0 [1]
N-[3-[4-(3-Tert-butylphenyl)phenyl]-1-[2-(dimethylamino)ethylamino]-1-oxopropan-2-yl]-4-methoxy-3-(methoxymethyl)benzamideIC5050000.0 [1]
N-[1-[2-(Dimethylamino)ethylamino]-1-oxo-3-(4-phenylphenyl)propan-2-yl]-4-methoxy-3-(methoxymethyl)benzamideIC50100000.0 [1]
N-[(2R)-1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[6-[3-(trifluoromethoxy)phenyl]pyridin-3-yl]propan-2-yl]-5-methyl-4-propylthiophene-2-carboxamideIC50500.0 [1]
N-[(2R)-1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[6-[3-(trifluoromethyl)phenyl]pyridin-3-yl]propan-2-yl]-5-methyl-4-propylthiophene-2-carboxamideIC50700.0 [1]
3-Ethoxy-4-methyl-N-[(2R)-1-oxo-1-[[(3R)-pyrrolidin-3-yl]amino]-3-[6-[3-(trifluoromethoxy)phenyl]pyridin-3-yl]propan-2-yl]benzamideIC502000.0 [1]
N-[(2R)-1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-4-methoxy-3-(methoxymethyl)benzamideIC502600.0 [1]
N-[(2S)-1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-4-methoxy-3-(methoxymethyl)benzamideIC502000.0 [1]
N-[(2R)-1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-5-methyl-4-propylthiophene-2-carboxamideIC50150.0 [1]
N-[(2S)-1-[2-(Dimethylamino)ethylamino]-1-oxo-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-5-methyl-4-propylthiophene-2-carboxamideIC504500.0 [1]
(2R)-2-[(5-Methyl-4-propylthiophene-2-carbonyl)amino]-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propanoic acidIC501700.0 [1]
(2S)-2-[(5-Methyl-4-propylthiophene-2-carbonyl)amino]-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propanoic acidIC5018000.0 [1]
4-Methyl-N-[(2R)-1-oxo-1-[[(3R)-pyrrolidin-3-yl]amino]-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-3-[(E)-prop-1-enyl]benzamideIC50190.0 [1]
4-Methyl-N-[(2S)-1-oxo-1-[[(3R)-pyrrolidin-3-yl]amino]-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propan-2-yl]-3-[(E)-prop-1-enyl]benzamideIC50520.0 [1]
(2R)-2-[[4-Methyl-3-[(E)-prop-1-enyl]benzoyl]amino]-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propanoic acidIC504800.0 [1]
(2S)-2-[[4-Methyl-3-[(E)-prop-1-enyl]benzoyl]amino]-3-[4-[3-(trifluoromethyl)phenyl]phenyl]propanoic acidIC5010200.0 [1]
N-(3-Aminopropyl)-N-[(1R)-1-(5-benzyl-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamideIC50100000.0 [1]
Items per page: 1 - 10 of 37
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References

This online tool may be cited as follows

MLA

"Quest Database™ Kinesin-like protein KIFC1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/kinesin-like-protein-kifc1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Kinesin-like protein KIFC1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/kinesin-like-protein-kifc1-inhibitors-ic50-ki.
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