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Janus Kinase (JAK) Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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RuxolitinibIC50100.0 [1]
CID 53344620IC5027.0 [1]
[2-[6-(2-Ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl]-(5-piperidin-1-ylpyrazin-2-yl)methanoneIC5070.3 [1]
4-[3-(1h-Benzimidazol-2-Yl)-1h-Indazol-6-Yl]-3-EthylphenolIC5010.5 [1]
6-(2-Ethyl-4-Hydroxyphenyl)-1h-Indazole-3-CarboxamideIC5019.1 [1]
6-(2-Ethyl-4-Hydroxyphenyl)-N-(6-Methylpyridin-3-Yl)-1h-Indazole-3-CarboxamideIC50277.8 [1]
6-(2-Methoxy-4-hydroxyphenyl)-3-1H-benzoimidazol-2-yl-1H-indazoleIC5057.8 [1]
3-1H-Benzoimidazol-2-yl-6-(3-hydroxyphenyl)-1H-indazoleIC50572.7 [1]
[2-[6-(2-Ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl]-(4-fluorophenyl)methanoneIC5035.0 [1]
4-[3-(5-Benzyl-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl]-5-ethyl-2-fluorophenolIC5030.4 [1]
3-Ethyl-4-[3-(5-methyl-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl]phenolIC5018.6 [1]
3-Ethyl-4-[3-(5-methylsulfonyl-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl]phenolIC5039.1 [1]
[(3R)-3-(3-Hydroxyphenyl)sulfonylpyrrolidin-1-yl]-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]methanoneIC50343.0 [1]
4-[3-(1H-Benzimidazol-2-yl)-1H-indazol-6-yl]-3-propan-2-ylphenolIC50250.3 [1]
4-[3-(1H-Benzimidazol-2-yl)-1H-indazol-6-yl]-3-ethyl-2-fluorophenolIC50204.8 [1]
3-Ethyl-4-[3-(1H-imidazol-2-yl)-1H-indazol-6-yl]phenolIC5010.4 [1]
6-(2-Ethyl-4-hydroxyphenyl)-N,N-dimethyl-1H-indazole-3-carboxamideIC5010000.0 [1]
6-(2-Ethyl-4-hydroxyphenyl)-N-methyl-1H-indazole-3-carboxamideIC509.1 [1]
1-[2-[6-(2-Ethyl-4-hydroxyphenyl)-1H-indazol-3-yl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl]ethanoneIC504.5 [1]
4-[3-(1H-Benzimidazol-2-yl)-1H-indazol-6-yl]-3-propylphenolIC5075.4 [1]
4-[3-(1H-Benzimidazol-2-yl)-1H-indazol-6-yl]-5-ethyl-2-fluorophenolIC5047.9 [1]
(E)-2-[(3S)-3-[4-Amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrileIC505.0 [1]
Items per page: 1 - 10 of 22
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References

This online tool may be cited as follows

MLA

"Quest Database™ Janus Kinase (JAK) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/janus-kinase-jak-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Janus Kinase (JAK) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/janus-kinase-jak-inhibitors-ic50-ki.
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