| (4R)-4-[(1S)-1-Fluoroethyl]-3-[2-[[(1S)-1-[4-methyl-5-[2-(trifluoromethyl)pyridin-4-yl]pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one | IC50 | 3800.0 [1], 10000.0 [2] |
| 4-N-[2-(1,1-Difluoroethyl)pyridin-4-yl]-2-N-propan-2-yl-6-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 3-Fluoro-5-[[4-[(2-hydroxy-2-methylpropyl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]benzonitrile | IC50 | 50.0 [1] |
| 2-N-(3,3-Difluorocyclopentyl)-4-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[[4-(3,5-Difluoroanilino)-6-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3,5-triazin-2-yl]amino]-2-methylpropan-2-ol | IC50 | 50.0 [1] |
| 1-[4-[[4-(6-Chloropyridin-2-yl)-6-[(3,3-difluorocyclopentyl)amino]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-(6-Chloropyridin-2-yl)-6-[[(1R)-1-cyclopropylethyl]amino]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 3-[[4-(Tert-butylamino)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]benzonitrile | IC50 | 50.0 [1] |
| 3-[[4-[[2-(1,1-Difluoroethyl)pyridin-4-yl]amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]-2,2-dimethylpropanenitrile | IC50 | 50.0 [1] |
| 3-[[4-[[2-(1,1-Difluoroethyl)pyridin-4-yl]amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]butanenitrile | IC50 | 50.0 [1], 100.0 [2] |
| 6-(6-Chloropyridin-2-yl)-2-N,4-N-bis(1-cyclopropylpropyl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 6-(6-Chloropyridin-2-yl)-2-N,4-N-bis(3,3-difluorocyclopentyl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N,4-N-Bis[(1R)-1-cyclopropylethyl]-6-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 4-N-(3,3-Difluorocyclopentyl)-2-N-[3-(4-fluorophenyl)cyclobutyl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 4-N-[(1R)-1-Cyclopropylethyl]-6-[6-(trifluoromethyl)pyridin-2-yl]-2-N-(1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-[(1R)-1-Cyclopropylethyl]-4-N-(2-phenoxyethyl)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-Tert-butyl-4-N-[2-(1,1-difluoroethyl)pyridin-4-yl]-6-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[[4-(3-Chloroanilino)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]-2-methylpropan-2-ol | IC50 | 50.0 [1], 100.0 [2] |
| 4-N-[(1R)-1-Cyclopropylethyl]-2-N-(dicyclopropylmethyl)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 3-[[4-(Tert-butylamino)-6-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3,5-triazin-2-yl]amino]-5-fluorobenzonitrile | IC50 | 50.0 [1] |
| Vorasidenib | IC50 | 50.0 [1] |
| 6-(6-Chloropyridin-2-yl)-4-N-[(2R)-1,1,1-trifluoropropan-2-yl]-2-N-[(2S)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| (2S)-N-[(1S)-5-Chloro-1-[(3,3-difluorocyclobutyl)carbamoyl]-2,3-dihydroinden-1-yl]-1-(4-cyanopyridin-2-yl)-N-(3-fluorophenyl)-5-oxopyrrolidine-2-carboxamide | IC50 | 100.0 [1] |
| (2S)-1-(4-Cyanopyridin-2-yl)-N-[(1S)-1-[(3,3-difluorocyclobutyl)carbamoyl]-2,3-dihydroinden-1-yl]-N-(3,5-difluorophenyl)-5-oxopyrrolidine-2-carboxamide | IC50 | 100.0 [1] |
| 2-N-(3,3-Difluorocyclopentyl)-4-N-(2-phenylpyridin-4-yl)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(3,3-Difluorocyclobutyl)-4-N-(3,5-difluorophenyl)-6-(3,6-difluoropyridin-2-yl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-[(2,2-Difluorospiro[3.3]heptan-6-yl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 6-(6-Chloropyridin-2-yl)-2-N-(3,3-difluorocyclopentyl)-4-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(3,3-Difluorocyclopentyl)-4-N-(3,5-difluorophenyl)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 6-(6-Chloropyridin-2-yl)-4-N-(cyclopropylmethyl)-2-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(4,4-Difluorocyclohexyl)-4-N-(2-phenylpyridin-4-yl)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(4,4-Difluorocyclohexyl)-4-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 4-N-(Cyclopropylmethyl)-6-[3-(trifluoromethyl)pyrazol-1-yl]-2-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(3,3-Difluorocyclobutyl)-6-[3-(trifluoromethyl)pyrazol-1-yl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-[(2-Hydroxy-2-methylpropyl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 2-N-[(1R)-3,3-Difluorocyclopentyl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(3,3-Difluorocyclopentyl)-6-[3-(trifluoromethyl)pyrazol-1-yl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 4-N-[(2,2-Difluorocyclopropyl)methyl]-2-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-[(1S)-3,3-Difluorocyclopentyl]-4-N-[2-(1,1-difluoroethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-[(1S)-3,3-Difluorocyclopentyl]-6-[6-(trifluoromethyl)pyrazin-2-yl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-[(1R)-3,3-Difluorocyclopentyl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[2-(trifluoromethyl)pyrimidin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-[(1S)-3,3-Difluorocyclopentyl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-[(1S)-3,3-Difluorocyclopentyl]-6-[3-(trifluoromethyl)pyrazol-1-yl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(2,2-Difluorospiro[3.3]heptan-6-yl)-6-[6-(trifluoromethyl)pyrazin-2-yl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 3-[[4-[(3,3-Difluorocyclobutyl)amino]-6-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-1,3,5-triazin-2-yl]amino]-5-fluorobenzonitrile | IC50 | 50.0 [1] |
| 4-[[4-[(3,3-Difluorocyclobutyl)amino]-6-[3-(trifluoromethyl)pyrazol-1-yl]-1,3,5-triazin-2-yl]amino]pyridine-2-carbonitrile | IC50 | 50.0 [1] |
| 6-[6-(Trifluoromethyl)pyrazin-2-yl]-2-N,4-N-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(3,3-Difluorocyclopentyl)-4-N-[5-(trifluoromethyl)pyridin-3-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-[6-(1,1-Difluoroethyl)pyridin-2-yl]-6-[[(2S)-1,1,1-trifluoropropan-2-yl]amino]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 2-N-(3,3-Difluorocyclobutyl)-4-N-(3,5-difluorophenyl)-6-[3-(trifluoromethyl)pyrazol-1-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-[[(1S)-3,3-Difluorocyclopentyl]amino]-6-[2-(trifluoromethyl)pyrimidin-4-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 4-N-[2-(Trifluoromethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-2-N-(1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 4-N-[(1S)-3,3-Difluorocyclopentyl]-2-N-[(1R)-3,3-difluorocyclopentyl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 6-(6-Amino-3-fluoropyridin-2-yl)-2-N-(4,4-difluorocyclohexyl)-4-N-(3,5-difluorophenyl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-[(1S)-3,3-Difluorocyclopentyl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[2-(trifluoromethyl)pyrimidin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 4-N-[2-(4-Chlorophenyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-2-N-[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N-(4,4-Difluorocyclohexyl)-4-N-[2-(1,1-difluoroethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-[[(1R)-3,3-Difluorocyclopentyl]amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[(3,3-Difluorocyclopentyl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[(4,4-Difluorocyclohexyl)amino]-6-[6-(trifluoromethyl)pyrazin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 3-[[4-[6-(1,1-Difluoroethyl)pyridin-2-yl]-6-[(2-hydroxy-2-methylpropyl)amino]-1,3,5-triazin-2-yl]amino]-5-fluorobenzonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[6-(1,1-Difluoroethyl)pyridin-2-yl]-6-[[(2R)-1,1,1-trifluoropropan-2-yl]amino]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 4-[4-[[4-[6-(Trifluoromethyl)pyridin-2-yl]-6-[[(2R)-1,1,1-trifluoropropan-2-yl]amino]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]benzonitrile | IC50 | 50.0 [1] |
| 4-[[4-[(2-Hydroxy-2-methylpropyl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridine-2-carbonitrile | IC50 | 100.0 [1] |
| 2-N-(3,3-Difluorocyclobutyl)-6-[6-(trifluoromethyl)pyrazin-2-yl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 3-[[4-(Cyclopropylmethylamino)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]-5-fluorobenzonitrile | IC50 | 50.0 [1] |
| 3-[4,6-Bis[[(1R)-1-cyclopropylethyl]amino]-1,3,5-triazin-2-yl]phenol | IC50 | 50.0 [1] |
| 1-[4-[[4-[[(1R)-3,3-Difluorocyclopentyl]amino]-6-[6-(trifluoromethyl)pyrazin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 2-[[4-[[2-(1,1-Difluoroethyl)pyridin-4-yl]amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]propanenitrile | IC50 | 50.0 [1] |
| 4-[[4-[(3,3-Difluorocyclopentyl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridine-2-carbonitrile | IC50 | 50.0 [1] |
| 4-N-[2-(4-Fluorophenyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-2-N-[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-(6-Chloropyridin-2-yl)-6-(2,2,2-trifluoroethylamino)-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 4-N-(2-Phenylpyridin-4-yl)-6-[6-(trifluoromethyl)pyridin-2-yl]-2-N-[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-[(3,3-Difluorocyclobutyl)amino]-6-[6-(1,1-difluoroethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 3-[[4-[(3,3-Difluorocyclobutyl)amino]-6-[3-(trifluoromethyl)pyrazol-1-yl]-1,3,5-triazin-2-yl]amino]-5-fluorobenzonitrile | IC50 | 50.0 [1] |
| 2-N-[(1R)-3,3-Difluorocyclopentyl]-6-[6-(trifluoromethyl)pyrazin-2-yl]-4-N-[2-(trifluoromethyl)pyridin-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 6-(6-Amino-3-fluoropyridin-2-yl)-2-N-(3,3-difluorocyclopentyl)-4-N-(3,5-difluorophenyl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 3-[[4-[(3,3-Difluorocyclopentyl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]-5-fluorobenzonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[[(1R)-3,3-Difluorocyclopentyl]amino]-6-[3-(trifluoromethyl)pyrazol-1-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[(3,3-Difluorocyclopentyl)amino]-6-[3-(trifluoromethyl)pyrazol-1-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 4-N-[(3,3-Difluorocyclobutyl)methyl]-2-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 3-[[4-[[(1R)-1-Cyclopropylethyl]amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]butanenitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[(3,3-Difluorocyclopentyl)amino]-6-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 6-(6-Amino-3-fluoropyridin-2-yl)-2-N,4-N-bis(4,4-difluorocyclohexyl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-[[(1S)-3,3-Difluorocyclopentyl]amino]-6-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 1-[[4-[6-(1,1-Difluoroethyl)pyridin-2-yl]-6-[3-fluoro-5-(trifluoromethyl)anilino]-1,3,5-triazin-2-yl]amino]-2-methylpropan-2-ol | IC50 | 50.0 [1] |
| 2-N-[(1R)-3,3-Difluorocyclopentyl]-4-N-[2-(1,1-difluoroethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 4-[[4-(Tert-butylamino)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridine-2-carbonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[[(1S)-3,3-Difluorocyclopentyl]amino]-6-[3-(trifluoromethyl)pyrazol-1-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[(4,4-Difluorocyclohexyl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-(2,2,2-Trifluoroethylamino)-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 2-N-(2,2-Difluorospiro[3.3]heptan-6-yl)-4-N-[2-(trifluoromethyl)pyridin-4-yl]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 1-[4-[[4-[(3,3-Difluorocyclobutyl)amino]-6-[6-(trifluoromethyl)pyrazin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 6-(6-Chloropyrazin-2-yl)-2-N-(3,3-difluorocyclobutyl)-4-N-(3,5-difluorophenyl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 6-(6-Chloropyrazin-2-yl)-2-N-(3,3-difluorocyclopentyl)-4-N-(3,5-difluorophenyl)-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 3-[[4-[[2-(1,1-Difluoroethyl)pyridin-4-yl]amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]-3-methylbutanenitrile | IC50 | 50.0 [1] |
| 1-[4-[[4-[(3,3-Difluorocyclobutyl)amino]-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl]amino]pyridin-2-yl]cyclopropane-1-carbonitrile | IC50 | 50.0 [1] |
| 2-N,4-N-Bis(4,4-difluorocyclohexyl)-6-[2-(trifluoromethyl)-1,3-thiazol-4-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N,4-N-Bis(3,3-difluorocyclobutyl)-6-[6-(trifluoromethoxy)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |
| 2-N,4-N-Bis(4,4-difluorocyclohexyl)-6-[6-(difluoromethyl)pyridin-2-yl]-1,3,5-triazine-2,4-diamine | IC50 | 50.0 [1] |