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Intestinal alkaline phosphatase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
LevamisoleIC505000.0 [1], 20210.0 [2], 200000.0 [3], 400000.0 [4]
PhenylalanineIC505000.0 [1], 80200.0 [2], 100000.0 [3]
6-(1-Benzothiophen-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole;hydrochlorideIC50400000.0 [1]
2-(5,6-Dihydroimidazo[2,1-b][1,3]thiazol-6-yl)-1-benzothiophen-5-amine;hydrochlorideIC50400000.0 [1]
6-(1-Benzothiophen-2-yl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochlorideIC50400000.0 [1]
6-(5-Nitro-1-benzothiophen-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazoleIC50400000.0 [1]
TryptophanIC505000.0 [1]
LeucineIC505000.0 [1]
TheophyllineIC505000.0 [1]
L-HomoarginineIC505000.0 [1]
(S)-2-Amino-4-methylpentanamideIC505000.0 [1]
2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamideIC50100000.0 [1]
1-(3,4-Dihydroxyphenyl)-2-(1-imidazolyl)ethanoneIC5030200.0 [1]
1-(3,4-Dihydroxyphenyl)-2-[(4,6-dimethyl-2-pyrimidinyl)thio]ethanoneIC5049500.0 [1]
CID 24790981IC50100000.0 [1]
3-Pyridinecarboxamide, 5-[[(5-chloro-2-methoxyphenyl)sulfonyl]amino]-IC5080000.0 [1]
N-(2,5-Dimethylphenyl)-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamideIC5027600.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 4-chloro-3-nitrobenzenesulfonateIC504060.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) ethanesulfonateIC504180.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 4-nitrobenzenesulfonateIC501110.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) ethanesulfonateIC504060.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) butane-1-sulfonateIC506290.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 4-chlorobenzenesulfonateIC507030.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) methanesulfonateIC503580.0 [1]
(4-Methyl-8-nitro-2-oxochromen-7-yl) 4-chloro-3-nitrobenzenesulfonateIC504650.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 3-nitrobenzenesulfonateIC505160.0 [1]
[8-(2,5-Dichlorophenyl)sulfonyloxy-4-methyl-2-oxochromen-7-yl] 2,5-dichlorobenzenesulfonateIC503210.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) octane-1-sulfonateIC502810.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) butane-1-sulfonateIC503220.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 4-propylbenzenesulfonateIC504630.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 2,5-dichlorobenzenesulfonateIC502260.0 [1]
(4-Methyl-8-nitro-2-oxochromen-7-yl) 4-octylbenzenesulfonateIC503060.0 [1]
[4-Methyl-8-(4-nitrophenyl)sulfonyloxy-2-oxochromen-7-yl] 4-nitrobenzenesulfonateIC504570.0 [1]
(8-Ethylsulfonyloxy-4-methyl-2-oxochromen-7-yl) ethanesulfonateIC502870.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 2-nitrobenzenesulfonateIC505490.0 [1]
(4-Methyl-8-octylsulfonyloxy-2-oxochromen-7-yl) octane-1-sulfonateIC5010300.0 [1]
[8-(4-Chlorophenyl)sulfonyloxy-4-methyl-2-oxochromen-7-yl] 4-chlorobenzenesulfonateIC5020600.0 [1]
(4-Methyl-2-oxochromen-7-yl) 4-chloro-3-nitrobenzenesulfonateIC502720.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 4-methoxybenzenesulfonateIC503590.0 [1]
(4-Methyl-2-oxochromen-7-yl) 2,4,5-trichlorobenzenesulfonateIC501330.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 4-methoxybenzenesulfonateIC502130.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) octane-1-sulfonateIC503120.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 4-chlorobenzenesulfonateIC5013100.0 [1]
[4-Methyl-2-oxo-8-(4-propylphenyl)sulfonyloxychromen-7-yl] 4-propylbenzenesulfonateIC505950.0 [1]
2-(3,4-Dimethylphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC501750.0 [1]
(3Z)-3-[(2-Methylphenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC503750.0 [1]
2-(Prop-2-enylamino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50890.0 [1]
2-(Butylamino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50710.0 [1]
(3Z)-3-[(3-Fluorophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC509930.0 [1]
2-[Amino(methyl)amino]-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC502220.0 [1]
(3Z)-3-[(4-Chlorophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC504350.0 [1]
2-(3-Fluorophenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50740.0 [1]
2-(3-Nitrophenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50480.0 [1]
(3Z)-3-[(2-Bromophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC507430.0 [1]
(3Z)-3-[(4-Bromophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC503690.0 [1]
(3Z)-3-[(2,6-Difluorophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC5010600.0 [1]
2-(Pentylamino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50760.0 [1]
2-(2-Methoxyphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50100000.0 [1]
2-(2-Fluorophenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50100000.0 [1]
2-(4-Ethoxyphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50790.0 [1]
2-(Propylamino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50310.0 [1]
2-(4-Methylphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50360.0 [1]
2-(4-Aminoanilino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50710.0 [1]
2-(4-Methoxyphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50480.0 [1]
2-(4-Ethylphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC504550.0 [1]
(3Z)-3-[(3-Methoxyphenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC501040.0 [1]
2-(4-Propan-2-ylanilino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC5031500.0 [1]
(3Z)-3-[(3-Bromophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC502550.0 [1]
2-Phenyl-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50430.0 [1]
2-(2-Ethoxyphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50100000.0 [1]
2-(3-Phenylphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC501670.0 [1]
2-[2-(Dimethylamino)ethylamino]-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC503750.0 [1]
2-[4-(Trifluoromethoxy)phenyl]-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50240.0 [1]
(3Z)-3-[(2,4-Dichlorophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC504960.0 [1]
2-(Dibutylamino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC504630.0 [1]
2-(3-Methoxyanilino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50440.0 [1]
(3Z)-3-[(4-Fluorophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC503060.0 [1]
3-[5-Oxo-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl]benzonitrileIC501120.0 [1]
2-(3,5-Dimethoxyphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50760.0 [1]
2-(3,5-Dimethylphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50460.0 [1]
2-(4-Ethoxyanilino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC502020.0 [1]
7-(Trifluoromethyl)-2-[3-(trifluoromethyl)phenyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50680.0 [1]
(3Z)-3-(3-Chlorobenzylidene)-2,3-dihydro-4H-1,2-benzothiazin-4-one 1,1-dioxideIC503770.0 [1]
(3Z)-3-(3-Hydroxybenzylidene)-2,3-dihydro-4H-1,2-benzothiazin-4-one 1,1-dioxideIC501210.0 [1]
(3Z)-3-(2-Methoxybenzylidene)-2,3-dihydro-4H-1,2-benzothiazin-4-one 1,1-dioxideIC501240.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) benzenesulfonateIC505520.0 [1]
1-(3,4-Dihydroxyphenyl)-2-(2-ethyl-1-imidazolyl)ethanoneIC50100000.0 [1]
1-(3,4-Dihydroxyphenyl)-2-(2-methyl-1-imidazolyl)ethanoneIC5064600.0 [1]
2-(Benzimidazol-1-yl)-1-(3,4-dihydroxyphenyl)ethanoneIC5014800.0 [1]
1-(3,4-Dihydroxyphenyl)-2-(2-methyl-1-benzimidazolyl)ethanoneIC50100000.0 [1]
1-(3,4-Dihydroxyphenyl)-2-(4-methyl-1-pyrazolyl)ethanoneIC5053300.0 [1]
(4-Methyl-2-oxochromen-7-yl) 2-methyl-5-nitrobenzenesulfonateIC503910.0 [1]
(3Z)-3-Benzylidene-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC501780.0 [1]
(3Z)-3-[(4-Methoxyphenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC501530.0 [1]
Items per page: 1 - 10 of 94
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References

This online tool may be cited as follows

MLA

"Quest Database™ Intestinal alkaline phosphatase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/intestinal-alkaline-phosphatase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Intestinal alkaline phosphatase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/intestinal-alkaline-phosphatase-inhibitors-ic50-ki.
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