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Interleukin-6 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
PrednisoloneIC504.2 [1]
BergeninIC50208.0 [1]
FosdagrocoratIC5060.0 [1]
(5S)-5-[[(3As,8bR)-8b-hydroxy-2,3a-dihydro-1H-furo[2,3-b]indol-4-yl]methyl]-2-butyl-3,5-dimethyl-4-methylidenecyclopent-2-en-1-oneIC5020500.0 [1]
2-N-(4-Ethylphenyl)-1,3-benzoxazole-2,5-diamineIC5018900.0 [1]
N-[2-(4-Ethylanilino)-1,3-benzoxazol-5-yl]benzamideIC505800.0 [1]
(4Bs,7S,8aR)-4b-benzyl-7-hydroxy-N-[(2-methylpyridin-3-yl)methyl]-7-(3,3,3-trifluoropropyl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamideIC5036.4 [1]
(4Bs,7R,8aR)-4b-benzyl-N-(3,5-dimethylpyrazin-2-yl)-7-hydroxy-7-(trifluoromethyl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamideIC504.0 [1]
(4Bs,7S,8aR)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(3,3,3-trifluoropropyl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamideIC501.1 [1]
(4Bs,7R,8aS)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-5,6,8,8a-tetrahydrophenanthrene-2-carboxamideIC502.8 [1]
(4Bs,7R,8aS)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-10-oxo-7-(trifluoromethyl)-6,8,8a,9-tetrahydro-5H-phenanthrene-2-carboxamideIC501.1 [1]
(4Bs,7R,8aR)-4b-benzyl-7-hydroxy-N-(2-methyl-1-oxidopyridin-1-ium-3-yl)-7-(trifluoromethyl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamideIC502.1 [1]
(4Bs,7S,8aR)-4b-benzyl-N-(2,4-dimethylpyrimidin-5-yl)-7-hydroxy-7-(3,3,3-trifluoropropyl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamideIC50291.0 [1]
(4Bs,7R,8aR,10R)-4b-benzyl-7,10-dihydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamideIC507.0 [1]
(4Bs,7R,8aR)-4b-benzyl-7-(difluoromethyl)-7-hydroxy-N-(2-methylpyridin-3-yl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamideIC504.3 [1]
(4Bs,7R,8aR)-4b-benzyl-7-hydroxy-N-(4-methylpyridin-3-yl)-7-(trifluoromethyl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamideIC501.3 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Interleukin-6 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/interleukin-6-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Interleukin-6 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/interleukin-6-inhibitors-ic50-ki.
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