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Intercellular adhesion molecule-1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamideIC5025.0 [1], 10000.0 [2], 15000.0 [3], 30000.0 [4]
N-Methyl-4-(4-chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamideIC5010.0 [1], 15.0 [2], 17.0 [3]
4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid amideIC503.0 [1], 5.0 [2], 6.0 [3]
4-[4-[2-(2-Methoxyethoxy)ethoxymethyl]phenoxy]-N-methylthieno[2,3-c]pyridine-2-carboxamideIC502.0 [1], 5.0 [2]
3-Isopropoxy-5-methoxybenzo(b)thiophene-2-carboxamideIC50140.0 [1], 390.0 [2]
4-(Toluene-4-sulfinyl)-thieno[2,3-c]pyridine-2-carboxylic acid amideIC504000.0 [1]
4-(4-Chlorophenylthio)thieno[2,3-c]pyridine-2-carboxamideIC5048.0 [1]
4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxylic acidIC503700.0 [1], 4000.0 [2]
LifitegrastIC502.98 [1]
5-Methoxy-3-(1-methylethoxy)benzo(b)thiophene-2-carboxamide-1-oxideIC504000.0 [1]
6-Ethylthieno[2,3-d]pyrimidin-4(3H)-oneIC50100000.0 [1]
2-Propen-1-one, 1-(4-acetyl-1-piperazinyl)-3-(4-((2-(1-methylethyl)phenyl)thio)-3-nitrophenyl)-IC5035.0 [1]
5-(6-Ethylthieno[2,3-d]pyrimidin-4-yl)sulfanyl-1,3,4-thiadiazol-2-amineIC506300.0 [1]
4-Chloro-6-ethylthieno[2,3-d]pyrimidineIC50100000.0 [1]
3-[3-Chloro-4-(2,4-dichlorophenylthio)phenyl]-1-(4-acetylpiperazino)-2-propene-1-oneIC50240.0 [1]
8-[[4-(Dimethylsulfamoylamino)piperidin-1-yl]methyl]-10H-pyrazino[2,3-b][1,4]benzothiazineIC50270.0 [1]
N-Methyl-4-(4-(trifluoromethyl)phenoxy)thieno(2,3-C)pyridine-2-carboxamideIC501.0 [1]
3-Isopropoxy-5-hydroxybenzo[b]thiophene-2-carboxamideIC503500.0 [1]
N-Methyl-3-isopropoxy-5-methoxybenzo[b]thiophene-2-carboxamideIC506600.0 [1]
3-Isopropoxy-5-methoxy-2-carbamoylbenzo[b]thiophene 1,1-dioxideIC5030000.0 [1]
4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid amideIC502.0 [1]
4-(4-Acetylamino-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid amideIC50150.0 [1]
3-Isopropoxy-7-methoxybenzo[b]thiophene-2-carboxamideIC5030000.0 [1]
2-[3-(10H-Pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)-3-azabicyclo[3.3.1]nonan-9-yl]acetic acidIC502300.0 [1]
4-(4-Methylphenoxy)thieno[2,3-c]pyridine-2-carboxamideIC5020.0 [1]
4-(4-Chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamideIC509.0 [1]
4-(4-Chlorophenoxy)-N,N-dimethylthieno[2,3-c]pyridine-2-carboxamideIC50180.0 [1]
N-Ethyl-4-(4-chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamideIC5034.0 [1]
4-(4-Methoxy-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid amideIC50430.0 [1]
3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl]-N-[3-(2-oxo-pyrrolidin-1-yl)-propyl]-acrylamideIC50700.0 [1]
(E)-3-[4-[2-[[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]methyl]phenyl]sulfanyl-3-chlorophenyl]-1-morpholin-4-ylprop-2-en-1-oneIC50360.0 [1]
3-[3-Chloro-4-[2-(3-morpholino-3-oxo-1-propenyl)phenylthio]phenyl]-1-morpholino-2-propene-1-oneIC50190.0 [1]
2-(4-p-Tolylsulfanyl-thieno[2,3-c]pyridin-2-ylmethyleneaminooxy)-acetamideIC501400.0 [1]
4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carbaldehyde O-benzyl-oximeIC504000.0 [1]
4-[4-[2-[2-(2-Ethoxyethoxy)ethoxy]-1,1-difluoroethyl]phenoxy]-N-methylthieno[2,3-c]pyridine-2-carboxamideIC5026.0 [1]
4-(3-Bromophenoxy)thieno[2,3-c]pyridine-2-carboxamideIC50110.0 [1]
4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carbaldehyde O-phenyl-oximeIC504000.0 [1]
4-[3-(Ethoxycarbonyl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC50680.0 [1]
4-(2-Carbamoyl-thieno[2,3-c]pyridin-4-yloxy)-benzoic acid ethyl esterIC5018.0 [1]
4-(4-Chlorophenoxy)-N-(2-hydroxyethyl)thieno[2,3-c]pyridine-2-carboxamideIC50340.0 [1]
CID 10155661IC50320.0 [1]
4-(2-Bromo-4-chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamideIC50300.0 [1]
N-Methyl-4-[4-(trifluoromethoxy)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC5053.0 [1]
4-(4-Iodo-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid amideIC504.0 [1]
4-(4-Methylphenyl)sulfanyl-N-(3-morpholin-4-ylpropyl)thieno[2,3-c]pyridine-2-carboxamideIC504000.0 [1]
4-(4-Octylphenoxy)thieno[2,3-c]pyridine-2-carboxamideIC50490.0 [1]
3-[3-Nitro-4-(2-ethylphenylthio)phenyl]-1-(4-acetylpiperazino)-2-propene-1-oneIC50100.0 [1]
4-[(3,4-Dimethylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamideIC508.0 [1]
4-(2-Methyl-4-chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamideIC50580.0 [1]
N-(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carbonyl)-guanidineIC504000.0 [1]
4-[4-[1-(Hydroxymethyl)cyclopropyl]phenoxy]-N-methylthieno[2,3-c]pyridine-2-carboxamideIC5046.0 [1]
(4-p-Tolylsulfanyl-thieno[2,3-c]pyridin-2-ylmethyleneaminooxy)-acetic acidIC504000.0 [1]
4-[4-[1-[2-(2-Ethoxyethoxy)ethoxymethyl]cyclopropyl]phenoxy]-N-methylthieno[2,3-c]pyridine-2-carboxamideIC50130.0 [1]
Cam-IN-1IC505.0 [1]
4-p-Tolylsulfanyl-benzo[b]thiophene-2-carboxylic acid amideIC5019000.0 [1]
4-[(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanyl]thieno[2,3-c]pyridine-2-carboxamideIC5012000.0 [1]
Thieno[2,3-c]pyridine-2-carboxamide, 4-chloro-IC50360.0 [1]
4-(p-Tolylthio)thieno[2,3-c]pyridine-2-methanolIC50540.0 [1]
4-Cyclohexylsulfanyl-thieno[2,3-c]pyridine-2-carboxylic acid amideIC50840.0 [1]
(E)-3-[2-(2,4-Dichlorophenyl)sulfanylphenyl]-1-morpholin-4-ylprop-2-en-1-oneIC505300.0 [1]
4-(4-Acetylphenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamideIC5040.0 [1]
Chembl4170462IC50270.0 [1]
N-Methyl-4-[4-(morpholine-4-carbonyl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC50901.0 [1]
N-Methyl-4-[4-[3-(4-methylpiperazin-1-yl)propylamino]phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC50120.0 [1]
N-[1-(10H-Pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)piperidin-4-yl]morpholine-4-sulfonamideIC50270.0 [1]
4-(4-Amino-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid amideIC5042.0 [1]
4-(2-Allylphenoxy)thieno[2,3-c]pyridine-2-carboxamideIC50780.0 [1]
4-(3-Fluoro-4-chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamideIC5010.0 [1]
4-[4-[Cyclohexyl(cyclohexylcarbamoyl)carbamoyl]phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC50116.0 [1]
N-Methyl-4-[4-(3-methylimidazol-4-yl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC50360.0 [1]
4-[4-(3-Morpholin-4-yl-3-oxo-propenyl)-phenoxy]-thieno[2,3-c]pyridine-2-carboxylic acid amideIC5016.0 [1]
1,1,1-Trifluoro-N-[1-(10H-pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)piperidin-4-yl]methanesulfonamideIC50270.0 [1]
4-[4-[(E)-3-(2-Morpholin-4-ylethylamino)-3-oxoprop-1-enyl]phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC5032.0 [1]
N-[1-(10H-Pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)piperidin-4-yl]piperidine-1-sulfonamideIC50270.0 [1]
4-(4-Hydroxymethyl-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid amideIC5023.0 [1]
N-[1-(10H-Pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)piperidin-4-yl]benzenesulfonamideIC50270.0 [1]
8-(Piperidin-1-ylmethyl)-10H-pyrazino[2,3-b][1,4]benzothiazineIC50270.0 [1]
N-[[1-(10H-Pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)piperidin-4-yl]methyl]methanesulfonamideIC50270.0 [1]
N-(Methylsulfamoyl)-1-(10H-pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)piperidin-4-amineIC50270.0 [1]
N-Methyl-4-[4-(1H-pyrazole-1-yl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC504.0 [1]
N-Methyl-4-[4-(2H-tetrazol-5-yl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC501000.0 [1]
4-[3-(Trifluoromethyl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC50760.0 [1]
1-(10H-Pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)piperidine-3-carboxamideIC50270.0 [1]
8-[(4-Methylsulfonylpiperazin-1-yl)methyl]-10H-pyrazino[2,3-b][1,4]benzothiazineIC50270.0 [1]
8-[[4-(Sulfamoylamino)piperidin-1-yl]methyl]-10H-pyrazino[2,3-b][1,4]benzothiazineIC50270.0 [1]
8-(Azepan-1-ylmethyl)-10H-pyrazino[2,3-b][1,4]benzothiazineIC50270.0 [1]
4-[4-(Hydroxymethyl)phenoxy]-N-methylthieno[2,3-c]pyridine-2-carboxamideIC5031.0 [1]
1-[4-(10H-Pyrazino[2,3-b][1,4]benzothiazin-8-ylmethyl)piperazin-1-yl]ethanoneIC50270.0 [1]
N-Methyl-4-[4-(2-furyl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC505.0 [1]
n-Methyl-4-[4-(2-thienyl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC506.0 [1]
4-[4-(Methoxymethyl)phenoxy]-N-methylthieno[2,3-c]pyridine-2-carboxamideIC5017.0 [1]
4-[4-(Tetrahydro-pyran-2-yloxymethyl)-phenoxy]-thieno[2,3-c]pyridine-2-carboxylic acid amideIC501.4 [1]
4-[4-(1H-Imidazole-1-yl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC505.0 [1]
N-Methyl-4-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC5022.0 [1]
4-[4-[(E)-3-[2-(1H-Imidazol-5-yl)ethylamino]-3-oxoprop-1-enyl]phenoxy]-N-methylthieno[2,3-c]pyridine-2-carboxamideIC50670.0 [1]
N-Methyl-4-(4-morpholin-4-ylphenoxy)thieno[2,3-c]pyridine-2-carboxamideIC5079.0 [1]
N-Methyl-4-[4-(1H-imidazole-1-yl)phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC506.0 [1]
4-[4-[(E)-3-[2-[Bis(2-hydroxyethyl)amino]ethylamino]-3-oxoprop-1-enyl]phenoxy]thieno[2,3-c]pyridine-2-carboxamideIC50820.0 [1]
8-(Azetidin-1-ylmethyl)-10H-pyrazino[2,3-b][1,4]benzothiazineIC50270.0 [1]
4-[4-(4,5-Dihydro-1H-imidazol-2-yl)phenoxy]-N-methylthieno[2,3-c]pyridine-2-carboxamideIC50970.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Intercellular adhesion molecule-1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/intercellular-adhesion-molecule-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Intercellular adhesion molecule-1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/intercellular-adhesion-molecule-1-inhibitors-ic50-ki.
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