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Integrin alpha-V/beta-6 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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3-[[4-[(4-Methyl-2-pyridyl)amino]butyrylamino]acetylamino]-3-[4-(1-naphthyl)phenyl]propionic acidIC500.04 [1], 199.53 [2], 200.0 [3]
CilengitideIC50470.0 [1], 1656.0 [2], 10000.0 [3]
(3S)-3-[3-(3,5-Dimethylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC503.98 [1]
(3S)-3-[3-(3,5-Dimethylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.01 [1], 0.04 [2]
3-[[5-[(2-Pyridyl)amino]pentanoylamino]acetylamino]-3-(4-biphenylyl)propionic acidIC500.6 [1], 100.0 [2]
3-[[4-[(2-Pyridyl)amino]butyrylamino]acetylamino]-3-(3-nitrophenyl)propionic acidIC504.0 [1], 90.0 [2]
(3S)-3-(3-Morpholin-4-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC503.98 [1]
(3S)-3-(3-Morpholin-4-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.03 [1], 0.06 [2]
3-(3,5-Dichlorophenyl)-3-[[2-[(3-guanidinobenzoyl)amino]acetyl]amino]propanoic acidIC50158.49 [1]
3-(3,5-Dichlorophenyl)-3-[[2-[(3-guanidinobenzoyl)amino]acetyl]amino]propanoic acidKi2.0 [1]
4-[2-[5-[(4-Methyl-2-pyridyl)amino]pentanoyl]hydrazinocarbonyl]-3-(3,5-dichlorophenyl)butyric acidIC5044.0 [1], 1600.0 [2]
4-[2-[5-[(4-Methyl-2-pyridyl)amino]pentanoyl]hydrazinocarbonyl]-3-(4-biphenylyl)butyric acidIC5053.0 [1], 3800.0 [2]
3-[2-(5-Guanidinopentanoyl)hydrazinocarbonylamino]-3-phenylpropionic acidIC50460.0 [1], 9600.0 [2]
3-(3,5-Dichlorophenyl)-3-[[5-[(4-methylpyridin-2-yl)amino]pentanoylamino]carbamoylamino]propanoic acidIC501.7 [1], 300.0 [2]
3-[[5-[(4-Methyl-2-pyridyl)amino]pentanoylamino]acetylamino]-3-(3,5-dichlorophenyl)propionic acidIC500.4 [1], 300.0 [2]
3-[[2-[4-[(4-Methylpyridin-2-yl)amino]butanoylamino]acetyl]amino]-3-[3-(trifluoromethoxy)phenyl]propanoic acidIC500.15 [1], 30.0 [2]
3-[7-[(4-Methyl-2-pyridyl)amino]heptanoylamino]-3-(3-nitrophenyl)propionic acidIC5061.0 [1], 2100.0 [2]
(3S)-3-(3-Cyclopropyl-5-morpholin-4-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC503.98 [1]
(3S)-3-(3-Cyclopropyl-5-morpholin-4-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.08 [1]
(3S)-3-[3-(3,5-Dimethylpyrazol-1-yl)-5-morpholin-4-ylphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC507.94 [1]
(3S)-3-[3-(3,5-Dimethylpyrazol-1-yl)-5-morpholin-4-ylphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.03 [1]
(3S)-3-[3-(2,5-Dimethyl-1H-imidazol-4-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC502.51 [1]
(3S)-3-[3-(2,5-Dimethyl-1H-imidazol-4-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.04 [1]
(3S)-3-[3-[(3S)-Oxolan-3-yl]oxyphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC501.58 [1]
(3S)-3-[3-[(3S)-Oxolan-3-yl]oxyphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.04 [1]
(3S)-3-[3-[(3R)-Oxolan-3-yl]oxyphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC502.51 [1]
(3S)-3-[3-[(3R)-Oxolan-3-yl]oxyphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.06 [1]
(3S)-4-[(3R)-3-[2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]-3-[3-(triazol-1-yl)phenyl]butanoic acidIC503.16 [1]
(3S)-4-[(3R)-3-[2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]-3-[3-(triazol-1-yl)phenyl]butanoic acidKi0.04 [1]
(3S)-3-[3-(3-Methyl-1,2,4-triazol-4-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC503.98 [1]
(3S)-3-[3-(3-Methyl-1,2,4-triazol-4-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.05 [1]
(3S)-3-[3-(3,5-Dimethyl-1,2,4-triazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC503.98 [1]
(3S)-3-[3-(3,5-Dimethyl-1,2,4-triazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.06 [1]
(3S)-3-[3-(3-Methylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC503.98 [1]
(3S)-3-[3-(3-Methylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.08 [1]
(3S)-3-(3-Pyrazol-1-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC502.51 [1]
(3S)-3-(3-Pyrazol-1-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.1 [1]
(3S)-3-[3-(5-Methylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC501.58 [1]
(3S)-3-[3-(5-Methylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.06 [1]
(3S)-3-(3-Cyclopropylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidIC503.98 [1]
(3S)-3-(3-Cyclopropylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acidKi0.08 [1]
2-[(5S,8S,11R,14S)-8-Benzyl-14-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-11-propan-2-yl-1,2,4,7,10,13-hexazacyclopentadec-5-yl]acetic acidIC50530.0 [1], 2000.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoic acidIC5038200.0 [1], 86500.0 [2]
(3S)-4-[[(2S)-1-[[(2S)-5-Amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-4-oxobutanoic acidIC501200.0 [1], 1540.0 [2]
(3S)-3-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-2-[(2-Aminoacetyl)amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S,3S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acidIC5013800.0 [1], 28700.0 [2]
2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-7,8-dimethyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acidIC502400.0 [1], 37000.0 [2]
(3S)-3-(3,5-Dichlorophenyl)-3-[[3-phenylmethoxy-2-[5-(pyridin-2-ylamino)pentanoylamino]propanoyl]amino]propanoic acidIC50200.0 [1], 1000.0 [2]
2-[(5S,8R,11S,14S)-8-Benzyl-14-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-11-propan-2-yl-1,2,4,7,10,13-hexazacyclopentadec-5-yl]acetic acidIC506000.0 [1], 8400.0 [2]
Cyclo(-RGDfK)IC5068.0 [1]
CID 53340771IC501.4 [1]
CID 72949858IC501.5 [1]
(2-{4-[2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acidIC502568.0 [1]
(3S)-3-(1,3-Benzodioxol-5-yl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acidIC502660.0 [1]
(3S)-3-(3-Bromo-5-chloro-2-hydroxyphenyl)-3-[[2-[[5-[(5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino]pyridine-3-carbonyl]amino]acetyl]amino]propanoic acidIC501.13 [1]
3-(4-{2-Oxo-3-[4-(3-o-tolyl-ureido)phenyl]-2H-pyridin-1-ylmethyl}phenyl)-propionic acidKi10000.0 [1]
(3S)-3-(3-Bromo-5-chloro-2-hydroxyphenyl)-3-[[2-[[3-hydroxy-5-[(5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino]benzoyl]amino]acetyl]amino]propanoic acidIC5011.7 [1]
3-Phenyl-4-[4-[3-(2-pyridinylamino)propoxy]phenyl]butanoic acidIC5019800.0 [1]
3-(4-Methylphenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC505057.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[3-[2-(1-methyl-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-6-yl)ethoxy]-1,2-oxazol-5-yl]butanoic acidIC50323.0 [1]
3-(3,4-Difluorophenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC502119.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[3-[3-[6-(methylamino)pyridin-2-yl]propyl]-1,2,4-oxadiazol-5-yl]butanoic acidIC5010000.0 [1]
3-(1,3-Benzoxazol-6-yl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acidIC50486.0 [1]
3-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acidIC50189.0 [1]
3-(6-Methoxypyridin-3-yl)-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acidIC50164.0 [1]
3-(3,5-Dimethoxyphenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC501743.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-(2-hydroxyethyl)-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acidIC5025.9 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-yl)ethoxy]pyrazol-3-yl]butanoic acidIC50216.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-phenyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acidIC50352.0 [1]
3-(3-Fluorophenyl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acidIC50794.33 [1]
3-(3-Fluorophenyl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acidIC503730.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[3-[3-(4,5-dihydro-1H-imidazol-2-ylamino)propoxy]-1,2-oxazol-5-yl]butanoic acidIC506830.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-[6-(methylamino)pyridin-2-yl]ethoxy]pyrazol-3-yl]butanoic acidIC504762.0 [1]
3-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-4-[3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1,2-oxazol-5-yl]butanoic acidIC50131.0 [1]
3-(1,3-Benzodioxol-5-yl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acidIC50251.19 [1]
3-Pyridin-3-yl-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acidIC502420.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1H-pyrazol-5-yl]butanoic acidIC50674.0 [1]
2-[2-[6-[2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyridin-3-yl]cyclopropyl]acetic acidIC5010000.0 [1]
3-(2,3-Dihydro-1-benzofuran-6-yl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acidIC503020.0 [1]
3-(2-Cyclopropyl-1,3-thiazol-5-yl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC50313.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(1-methyl-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-6-yl)ethoxy]pyrazol-3-yl]butanoic acidIC501433.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-(carboxymethyl)-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acidIC50491.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethylsulfonyl]pyrazol-3-yl]butanoic acidIC501394.0 [1]
3-(3-Fluorophenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC501308.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1,2-oxazol-5-yl]butanoic acidIC50350.0 [1]
(3S)-3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acidIC50347.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethylsulfanyl]pyrazol-3-yl]butanoic acidIC504623.0 [1]
3-(2-Phenyl-1,3-thiazol-5-yl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC502671.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-butyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acidIC501633.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1-(2,2,2-trifluoroethyl)pyrazol-3-yl]butanoic acidIC50465.0 [1]
3-(6-Methoxypyridin-3-yl)-4-[3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1,2-oxazol-5-yl]butanoic acidIC5066.4 [1]
3-(6-Methoxypyridin-3-yl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC501323.0 [1]
3-(4-Chlorophenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC502444.0 [1]
3-(3-Fluoro-4-methoxyphenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC503263.0 [1]
3-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC504301.0 [1]
3-(1,3-Benzodioxol-5-yl)-4-[1-benzyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acidIC502108.0 [1]
3-(2-Cyclopropyl-1,3-thiazol-5-yl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acidIC501590.0 [1]
3-[2-(Methoxymethyl)-1,3-thiazol-5-yl]-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acidIC50841.0 [1]
3-(2-Fluorophenyl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acidIC501000.0 [1]
3-(2-Chlorophenyl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acidIC5010000.0 [1]
3-(2-Methylphenyl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acidIC50398.11 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Integrin alpha-V/beta-6 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/integrin-alpha-v-beta-6-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Integrin alpha-V/beta-6 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/integrin-alpha-v-beta-6-inhibitors-ic50-ki.
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