| 3-[[4-[(4-Methyl-2-pyridyl)amino]butyrylamino]acetylamino]-3-[4-(1-naphthyl)phenyl]propionic acid | IC50 | 0.04 [1], 199.53 [2], 200.0 [3] |
| Cilengitide | IC50 | 470.0 [1], 1656.0 [2], 10000.0 [3] |
| (3S)-3-[3-(3,5-Dimethylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 3.98 [1] |
| (3S)-3-[3-(3,5-Dimethylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.01 [1], 0.04 [2] |
| 3-[[5-[(2-Pyridyl)amino]pentanoylamino]acetylamino]-3-(4-biphenylyl)propionic acid | IC50 | 0.6 [1], 100.0 [2] |
| 3-[[4-[(2-Pyridyl)amino]butyrylamino]acetylamino]-3-(3-nitrophenyl)propionic acid | IC50 | 4.0 [1], 90.0 [2] |
| (3S)-3-(3-Morpholin-4-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 3.98 [1] |
| (3S)-3-(3-Morpholin-4-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.03 [1], 0.06 [2] |
| 3-(3,5-Dichlorophenyl)-3-[[2-[(3-guanidinobenzoyl)amino]acetyl]amino]propanoic acid | IC50 | 158.49 [1] |
| 3-(3,5-Dichlorophenyl)-3-[[2-[(3-guanidinobenzoyl)amino]acetyl]amino]propanoic acid | Ki | 2.0 [1] |
| 4-[2-[5-[(4-Methyl-2-pyridyl)amino]pentanoyl]hydrazinocarbonyl]-3-(3,5-dichlorophenyl)butyric acid | IC50 | 44.0 [1], 1600.0 [2] |
| 4-[2-[5-[(4-Methyl-2-pyridyl)amino]pentanoyl]hydrazinocarbonyl]-3-(4-biphenylyl)butyric acid | IC50 | 53.0 [1], 3800.0 [2] |
| 3-[2-(5-Guanidinopentanoyl)hydrazinocarbonylamino]-3-phenylpropionic acid | IC50 | 460.0 [1], 9600.0 [2] |
| 3-(3,5-Dichlorophenyl)-3-[[5-[(4-methylpyridin-2-yl)amino]pentanoylamino]carbamoylamino]propanoic acid | IC50 | 1.7 [1], 300.0 [2] |
| 3-[[5-[(4-Methyl-2-pyridyl)amino]pentanoylamino]acetylamino]-3-(3,5-dichlorophenyl)propionic acid | IC50 | 0.4 [1], 300.0 [2] |
| 3-[[2-[4-[(4-Methylpyridin-2-yl)amino]butanoylamino]acetyl]amino]-3-[3-(trifluoromethoxy)phenyl]propanoic acid | IC50 | 0.15 [1], 30.0 [2] |
| 3-[7-[(4-Methyl-2-pyridyl)amino]heptanoylamino]-3-(3-nitrophenyl)propionic acid | IC50 | 61.0 [1], 2100.0 [2] |
| (3S)-3-(3-Cyclopropyl-5-morpholin-4-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 3.98 [1] |
| (3S)-3-(3-Cyclopropyl-5-morpholin-4-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.08 [1] |
| (3S)-3-[3-(3,5-Dimethylpyrazol-1-yl)-5-morpholin-4-ylphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 7.94 [1] |
| (3S)-3-[3-(3,5-Dimethylpyrazol-1-yl)-5-morpholin-4-ylphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.03 [1] |
| (3S)-3-[3-(2,5-Dimethyl-1H-imidazol-4-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 2.51 [1] |
| (3S)-3-[3-(2,5-Dimethyl-1H-imidazol-4-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.04 [1] |
| (3S)-3-[3-[(3S)-Oxolan-3-yl]oxyphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 1.58 [1] |
| (3S)-3-[3-[(3S)-Oxolan-3-yl]oxyphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.04 [1] |
| (3S)-3-[3-[(3R)-Oxolan-3-yl]oxyphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 2.51 [1] |
| (3S)-3-[3-[(3R)-Oxolan-3-yl]oxyphenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.06 [1] |
| (3S)-4-[(3R)-3-[2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]-3-[3-(triazol-1-yl)phenyl]butanoic acid | IC50 | 3.16 [1] |
| (3S)-4-[(3R)-3-[2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]-3-[3-(triazol-1-yl)phenyl]butanoic acid | Ki | 0.04 [1] |
| (3S)-3-[3-(3-Methyl-1,2,4-triazol-4-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 3.98 [1] |
| (3S)-3-[3-(3-Methyl-1,2,4-triazol-4-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.05 [1] |
| (3S)-3-[3-(3,5-Dimethyl-1,2,4-triazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 3.98 [1] |
| (3S)-3-[3-(3,5-Dimethyl-1,2,4-triazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.06 [1] |
| (3S)-3-[3-(3-Methylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 3.98 [1] |
| (3S)-3-[3-(3-Methylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.08 [1] |
| (3S)-3-(3-Pyrazol-1-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 2.51 [1] |
| (3S)-3-(3-Pyrazol-1-ylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.1 [1] |
| (3S)-3-[3-(5-Methylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 1.58 [1] |
| (3S)-3-[3-(5-Methylpyrazol-1-yl)phenyl]-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.06 [1] |
| (3S)-3-(3-Cyclopropylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | IC50 | 3.98 [1] |
| (3S)-3-(3-Cyclopropylphenyl)-4-[(3R)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid | Ki | 0.08 [1] |
| 2-[(5S,8S,11R,14S)-8-Benzyl-14-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-11-propan-2-yl-1,2,4,7,10,13-hexazacyclopentadec-5-yl]acetic acid | IC50 | 530.0 [1], 2000.0 [2] |
| (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoic acid | IC50 | 38200.0 [1], 86500.0 [2] |
| (3S)-4-[[(2S)-1-[[(2S)-5-Amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-4-oxobutanoic acid | IC50 | 1200.0 [1], 1540.0 [2] |
| (3S)-3-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-2-[(2-Aminoacetyl)amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S,3S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid | IC50 | 13800.0 [1], 28700.0 [2] |
| 2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-7,8-dimethyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid | IC50 | 2400.0 [1], 37000.0 [2] |
| (3S)-3-(3,5-Dichlorophenyl)-3-[[3-phenylmethoxy-2-[5-(pyridin-2-ylamino)pentanoylamino]propanoyl]amino]propanoic acid | IC50 | 200.0 [1], 1000.0 [2] |
| 2-[(5S,8R,11S,14S)-8-Benzyl-14-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-11-propan-2-yl-1,2,4,7,10,13-hexazacyclopentadec-5-yl]acetic acid | IC50 | 6000.0 [1], 8400.0 [2] |
| Cyclo(-RGDfK) | IC50 | 68.0 [1] |
| CID 53340771 | IC50 | 1.4 [1] |
| CID 72949858 | IC50 | 1.5 [1] |
| (2-{4-[2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid | IC50 | 2568.0 [1] |
| (3S)-3-(1,3-Benzodioxol-5-yl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acid | IC50 | 2660.0 [1] |
| (3S)-3-(3-Bromo-5-chloro-2-hydroxyphenyl)-3-[[2-[[5-[(5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino]pyridine-3-carbonyl]amino]acetyl]amino]propanoic acid | IC50 | 1.13 [1] |
| 3-(4-{2-Oxo-3-[4-(3-o-tolyl-ureido)phenyl]-2H-pyridin-1-ylmethyl}phenyl)-propionic acid | Ki | 10000.0 [1] |
| (3S)-3-(3-Bromo-5-chloro-2-hydroxyphenyl)-3-[[2-[[3-hydroxy-5-[(5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino]benzoyl]amino]acetyl]amino]propanoic acid | IC50 | 11.7 [1] |
| 3-Phenyl-4-[4-[3-(2-pyridinylamino)propoxy]phenyl]butanoic acid | IC50 | 19800.0 [1] |
| 3-(4-Methylphenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 5057.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[3-[2-(1-methyl-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-6-yl)ethoxy]-1,2-oxazol-5-yl]butanoic acid | IC50 | 323.0 [1] |
| 3-(3,4-Difluorophenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 2119.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[3-[3-[6-(methylamino)pyridin-2-yl]propyl]-1,2,4-oxadiazol-5-yl]butanoic acid | IC50 | 10000.0 [1] |
| 3-(1,3-Benzoxazol-6-yl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acid | IC50 | 486.0 [1] |
| 3-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 189.0 [1] |
| 3-(6-Methoxypyridin-3-yl)-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 164.0 [1] |
| 3-(3,5-Dimethoxyphenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 1743.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-(2-hydroxyethyl)-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 25.9 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 216.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-phenyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 352.0 [1] |
| 3-(3-Fluorophenyl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acid | IC50 | 794.33 [1] |
| 3-(3-Fluorophenyl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acid | IC50 | 3730.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[3-[3-(4,5-dihydro-1H-imidazol-2-ylamino)propoxy]-1,2-oxazol-5-yl]butanoic acid | IC50 | 6830.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-[6-(methylamino)pyridin-2-yl]ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 4762.0 [1] |
| 3-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-4-[3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1,2-oxazol-5-yl]butanoic acid | IC50 | 131.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acid | IC50 | 251.19 [1] |
| 3-Pyridin-3-yl-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acid | IC50 | 2420.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1H-pyrazol-5-yl]butanoic acid | IC50 | 674.0 [1] |
| 2-[2-[6-[2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyridin-3-yl]cyclopropyl]acetic acid | IC50 | 10000.0 [1] |
| 3-(2,3-Dihydro-1-benzofuran-6-yl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acid | IC50 | 3020.0 [1] |
| 3-(2-Cyclopropyl-1,3-thiazol-5-yl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 313.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(1-methyl-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-6-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 1433.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-(carboxymethyl)-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 491.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethylsulfonyl]pyrazol-3-yl]butanoic acid | IC50 | 1394.0 [1] |
| 3-(3-Fluorophenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 1308.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1,2-oxazol-5-yl]butanoic acid | IC50 | 350.0 [1] |
| (3S)-3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 347.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-methyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethylsulfanyl]pyrazol-3-yl]butanoic acid | IC50 | 4623.0 [1] |
| 3-(2-Phenyl-1,3-thiazol-5-yl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 2671.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-butyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 1633.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1-(2,2,2-trifluoroethyl)pyrazol-3-yl]butanoic acid | IC50 | 465.0 [1] |
| 3-(6-Methoxypyridin-3-yl)-4-[3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]-1,2-oxazol-5-yl]butanoic acid | IC50 | 66.4 [1] |
| 3-(6-Methoxypyridin-3-yl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 1323.0 [1] |
| 3-(4-Chlorophenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 2444.0 [1] |
| 3-(3-Fluoro-4-methoxyphenyl)-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 3263.0 [1] |
| 3-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 4301.0 [1] |
| 3-(1,3-Benzodioxol-5-yl)-4-[1-benzyl-5-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]pyrazol-3-yl]butanoic acid | IC50 | 2108.0 [1] |
| 3-(2-Cyclopropyl-1,3-thiazol-5-yl)-4-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,2,4-oxadiazol-5-yl]butanoic acid | IC50 | 1590.0 [1] |
| 3-[2-(Methoxymethyl)-1,3-thiazol-5-yl]-4-[2-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1,3-thiazol-4-yl]butanoic acid | IC50 | 841.0 [1] |
| 3-(2-Fluorophenyl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acid | IC50 | 1000.0 [1] |
| 3-(2-Chlorophenyl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acid | IC50 | 10000.0 [1] |
| 3-(2-Methylphenyl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acid | IC50 | 398.11 [1] |