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Integrin alpha-4 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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4-[[(2S,4S)-1-[2-[3-Chloro-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC500.51 [1], 7.2 [2]
(8R,13R)-13-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-6,14-dioxo-10,11-dithia-7,15-diazaspiro[4.12]heptadecane-8-carboxylic acidIC500.5 [1], 24.0 [2]
4-[[(2S,4S)-4-Fluoro-1-[2-[2-(2-methylanilino)-1,3-benzoxazol-6-yl]acetyl]pyrrolidin-2-yl]methoxy]cyclohexane-1-carboxylic acidIC502.8 [1], 15.0 [2], 443.0 [3]
(2S)-2-[[(2S)-1-(3,5-Dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.07 [1], 1.5 [2]
(2S)-2-[[(2S,4R)-4-(Azetidin-1-yl)-1-(3-cyanophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.34 [1]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-pyrrolidin-1-ylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.16 [1]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-piperidin-1-ylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.11 [1]
(8S,13R)-13-[[1-Acetyl-3-(4-hydroxyphenyl)pyrrolidine-2-carbonyl]amino]-6,14-dioxo-11-thia-7,15-diazaspiro[4.12]heptadecane-8-carboxylic acidIC500.5 [1], 20.0 [2]
(8R,13R)-13-[[(2S)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-6,14-dioxo-10,11-dithia-7,15-diazaspiro[4.12]heptadecane-8-carboxylic acidIC500.7 [1], 12.0 [2]
4-[[(2S,4S)-4-Fluoro-1-[2-[3-methoxy-4-[(2-methoxyphenyl)carbamoylamino]phenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoic acidIC509.2 [1], 268.0 [2]
4-[[(2S,4S)-4-Fluoro-1-[2-[3-methoxy-4-[[2-(trifluoromethyl)phenyl]carbamoylamino]phenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoic acidIC50106.0 [1], 1000.0 [2]
4-[[(2S,4S)-4-Fluoro-1-[2-[3-methoxy-4-[(2-propan-2-ylphenyl)carbamoylamino]phenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoic acidIC50769.0 [1], 1000.0 [2]
4-[[(2S,4S)-4-Fluoro-1-[2-[3-methyl-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoic acidIC502.3 [1], 49.0 [2]
4-[[(2S,4S)-1-[2-[3-Ethyl-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC5015.0 [1], 282.0 [2]
4-[[(2S,4S)-4-Fluoro-1-[2-[4-[(2-methylphenyl)carbamoylamino]-3-propan-2-ylphenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoic acidIC50216.0 [1], 1000.0 [2]
4-[[(2S,4S)-4-Fluoro-1-[2-[4-[(2-methylphenyl)carbamoylamino]-3-(trifluoromethyl)phenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoic acidIC5015.0 [1], 486.0 [2]
4-[[(2S,4S)-1-[2-[3-Bromo-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC500.78 [1], 8.4 [2]
4-[[(2S,4S)-1-[2-[4-[(2-Chlorophenyl)carbamoylamino]-3-methylphenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC5013.0 [1], 416.0 [2]
4-[[(2S,4S)-1-[2-[3-Chloro-4-[(2-chlorophenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC501.3 [1], 81.0 [2]
4-[[(2S,4S)-1-[2-[3-Bromo-4-[(2-chlorophenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC501.3 [1], 51.0 [2]
4-[[(2S,4S)-1-[2-[4-[(2-Bromophenyl)carbamoylamino]-3-methylphenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC509.8 [1], 622.0 [2]
4-[[(2S,4S)-1-[2-[4-[(2-Bromophenyl)carbamoylamino]-3-chlorophenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC501.7 [1], 137.0 [2]
4-[[(2S,4S)-1-[2-[3-Bromo-4-[(2-bromophenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC501.4 [1], 95.0 [2]
4-[[(2S,4S)-1-[2-[3-Chloro-4-[(5-fluoro-2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC501.6 [1], 31.0 [2]
(2S)-2-[[(2S,4R)-4-Amino-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.09 [1], 0.4 [2]
(2S)-2-[[(2S,4R)-1-(3,5-Dichlorophenyl)sulfonyl-4-pyrrolidin-1-ylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.1 [1], 0.2 [2]
(2S)-2-[[(2S,4R)-4-(Cyclobutylamino)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.1 [1]
(2S)-2-[[(2S,4R)-1-(3,5-Dichlorophenyl)sulfonyl-4-piperidin-1-ylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.09 [1], 0.3 [2]
(8R,13R)-13-[[1-Acetyl-3-(4-hydroxyphenyl)pyrrolidine-2-carbonyl]amino]-6,14-dioxo-10,11-dithia-7,15-diazaspiro[4.12]heptadecane-8-carboxylic acidIC500.1 [1], 1.5 [2]
(8R,13S)-13-[[1-Acetyl-3-(4-hydroxyphenyl)pyrrolidine-2-carbonyl]amino]-6,14-dioxo-10-thia-7,15-diazaspiro[4.12]heptadecane-8-carboxylic acidIC502.7 [1], 220.0 [2]
(3R,6S,11S,14R)-6-[[(2S)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-(carboxymethyl)-2,5,13-trioxo-8,9-dithia-1,4,12-triazabicyclo[12.3.0]heptadecane-11-carboxylic acidIC501.8 [1], 200.0 [2]
(8R,13R)-13-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-6,14-dioxo-10,11-dithia-7,15-diazaspiro[4.13]octadecane-8-carboxylic acidIC5019.0 [1], 480.0 [2]
4-[[(2S,4S)-1-[2-[4-[(2-Bromophenyl)carbamoylamino]-2,5-dichlorophenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC507.5 [1], 1462.0 [2]
4-[[(2S,4S)-1-[2-[4-[(2-Bromophenyl)carbamoylamino]-5-chloro-2-methylphenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC504.8 [1], 629.0 [2]
4-[[(2S,4S)-1-[2-[3-Chloro-4-[(3-fluoro-2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC5012.0 [1], 745.0 [2]
4-[[(2S,4S)-1-[2-[3-Chloro-4-[(4-fluoro-2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC502.8 [1], 330.0 [2]
4-[[(2S,4S)-1-[2-[5-Chloro-4-[(2-chlorophenyl)carbamoylamino]-2-fluorophenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC502.9 [1], 332.0 [2]
4-[[(2S,4S)-1-[2-[2,5-Dichloro-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC502.2 [1], 63.0 [2]
4-[[(2S,4S)-1-[2-[5-Chloro-2-fluoro-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC501.8 [1], 44.0 [2]
4-[[(2S,4S)-1-[2-[5-Chloro-2-methyl-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC501.9 [1], 36.0 [2]
4-[[(2S,4S)-1-[2-[2,5-Dichloro-4-[(2-chlorophenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC503.4 [1], 630.0 [2]
4-[[(2S,4S)-1-[2-[5-Chloro-4-[(2-chlorophenyl)carbamoylamino]-2-methylphenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC503.5 [1], 394.0 [2]
4-[[(2S,4S)-1-[2-[4-[(2-Bromophenyl)carbamoylamino]-5-chloro-2-fluorophenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC504.3 [1], 688.0 [2]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-pyrazol-1-ylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.22 [1], 0.48 [2]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-indazol-1-ylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.25 [1], 2.01 [2]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-(4,5,6,7-tetrahydroindazol-1-yl)pyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.35 [1], 4.75 [2]
(2S)-2-[[(2S,4R)-4-(Benzimidazol-1-yl)-1-(3-cyanophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.08 [1], 0.5 [2]
(2S)-2-[[(2S,4R)-4-(Azepan-1-yl)-1-(3-cyanophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.42 [1]
(2S)-2-[[(2S,4R)-4-(Azocan-1-yl)-1-(3-cyanophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.25 [1]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-morpholin-4-ylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.13 [1]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-thiomorpholin-4-ylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.13 [1]
2-[[1-(3-Cyanophenyl)sulfonyl-4-(2-methylpiperidin-1-yl)pyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.11 [1]
2-[[1-(3-Cyanophenyl)sulfonyl-4-(3-methylpiperidin-1-yl)pyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.13 [1]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-(4-methylpiperidin-1-yl)pyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.16 [1]
2-[[1-(3-Cyanophenyl)sulfonyl-4-(3,5-dimethylpiperidin-1-yl)pyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.14 [1]
(2S)-2-[[(2S,4R)-1-(3-Cyanophenyl)sulfonyl-4-(3,3-dimethylpiperidin-1-yl)pyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.16 [1]
(2S)-2-[[(2S)-1-(3,5-Dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.11 [1], 49.0 [2]
4-[[(2S,4S)-4-Fluoro-1-[2-[3-methoxy-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoic acidIC501.2 [1], 3.7 [2]
4-[[(2S,4S)-1-[2-[4-[(2-Chlorophenyl)carbamoylamino]-3-methoxyphenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC500.87 [1], 6.2 [2]
4-[[(2S,4S)-1-[2-[4-[(2-Bromophenyl)carbamoylamino]-3-methoxyphenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acidIC501.6 [1], 16.0 [2]
(2S)-2-[[(2S,4R)-4-(Azetidin-1-yl)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.08 [1], 0.2 [2]
(S)-2-((S)-1-(3,5-Dichlorophenylsulfonyl)pyrrolidine-2-carboxamido)-3-phenylpropanoic acidIC501.4 [1]
(2S)-2-[[(2S)-1-(3,5-Dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(2-methoxyphenyl)phenyl]propanoic acidIC500.64 [1]
(2S)-3-[4-[4-(2-Cyanophenyl)piperazin-1-yl]phenyl]-2-[[(2S)-1-(4-methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acidIC5099.0 [1]
2-[[Cyclohexyl-(3,5-dichlorophenyl)sulfonylamino]methyl]-5-[(4-phenylphenyl)methyl]-1H-imidazole-4-carboxylic acidIC50237.0 [1]
(2S)-2-[[(2S,4S)-4-(Azetidin-1-yl)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(3,5-dichloropyridine-4-carbonyl)amino]phenyl]propanoic acidIC500.2 [1]
(8S)-14-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-6,15-dioxo-7,16-diazaspiro[4.13]octadecane-8-carboxylic acidIC50550.0 [1]
(8S,13E)-14-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-6,15-dioxo-7,16-diazaspiro[4.13]octadec-13-ene-8-carboxylic acidIC50330.0 [1]
(8S,12E)-13-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-6,14-dioxo-7,15-diazaspiro[4.12]heptadec-12-ene-8-carboxylic acidIC50160.0 [1]
(8S)-13-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-6,14-dioxo-7,15-diazaspiro[4.12]heptadecane-8-carboxylic acidIC5089.0 [1]
(8S,14S)-14-[[1-Acetyl-3-(4-hydroxyphenyl)pyrrolidine-2-carbonyl]amino]-6,15-dioxo-11-thia-7,16-diazaspiro[4.13]octadecane-8-carboxylic acidIC5035.0 [1]
(4R,12R)-12-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-7,7-diethyl-6,11-dioxo-1,2-dithia-5,10-diazacyclotridecane-4-carboxylic acidIC503.9 [1]
(4R,12R)-12-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-7,7-dimethyl-6,11-dioxo-1,2-dithia-5,10-diazacyclotridecane-4-carboxylic acidIC50112.0 [1]
(8R,13R)-13-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-6,14-dioxo-10,11-dithia-7,15-diazaspiro[4.11]hexadecane-8-carboxylic acidIC505.0 [1]
(2S)-2-[[(2S)-1-(4-Methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(4-phenylpiperazin-1-yl)phenyl]propanoic acidIC50123.0 [1]
(2S)-3-[4-[4-(2-Methoxyphenyl)piperazin-1-yl]phenyl]-2-[[(2S)-1-(4-methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acidIC50135.0 [1]
(2S)-3-[4-[4-(3-Methoxyphenyl)piperazin-1-yl]phenyl]-2-[[(2S)-1-(4-methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acidIC50170.0 [1]
(2S)-3-[4-[4-(4-Methoxyphenyl)piperazin-1-yl]phenyl]-2-[[(2S)-1-(4-methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acidIC50152.0 [1]
(2S)-3-[4-[4-(4-Methylphenyl)piperazin-1-yl]phenyl]-2-[[(2S)-1-(4-methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acidIC50353.0 [1]
(2S)-3-[4-[4-(2,3-Dimethylphenyl)piperazin-1-yl]phenyl]-2-[[(2S)-1-(4-methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acidIC50327.0 [1]
(2S)-2-[[(2S)-1-(4-Methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[4-(4-phenylphenyl)piperazin-1-yl]phenyl]propanoic acidIC50450.0 [1]
(2S)-2-[[(2S)-1-(4-Methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[4-(4-nitrophenyl)piperazin-1-yl]phenyl]propanoic acidIC50143.0 [1]
(2S)-2-[[(2S)-1-(4-Methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]propanoic acidIC50239.0 [1]
(2S)-2-[[(2S)-1-(4-Methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]propanoic acidIC5075.0 [1]
(2S)-2-[[(2S)-1-(4-Methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(4-pyridin-2-ylpiperazin-1-yl)phenyl]propanoic acidIC50179.0 [1]
(2S)-2-[[(2S)-1-(4-Methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(4-methylpiperazin-1-yl)phenyl]propanoic acidIC50235.0 [1]
(2S)-3-[4-(4-Benzylpiperazin-1-yl)phenyl]-2-[[(2S)-1-(4-methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acidIC50222.0 [1]
(2S)-3-[4-[4-(3-Ethoxy-3-oxopropyl)piperazin-1-yl]phenyl]-2-[[(2S)-1-(4-methylphenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acidIC50130.0 [1]
(2S)-2-[[(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carbonyl]amino]-3-[4-(4-phenylpiperazin-1-yl)phenyl]propanoic acidIC5076.0 [1]
(2S)-2-[[(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carbonyl]amino]-3-[4-[4-(2-nitrophenyl)piperazin-1-yl]phenyl]propanoic acidIC5069.0 [1]
(2S)-2-[[(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carbonyl]amino]-3-[4-[4-(2-cyanophenyl)piperazin-1-yl]phenyl]propanoic acidIC5067.0 [1]
(2S)-2-[[(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carbonyl]amino]-3-[4-[4-(4-cyanophenyl)piperazin-1-yl]phenyl]propanoic acidIC50101.0 [1]
(2S)-2-[[(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carbonyl]amino]-3-[4-[4-(2,6-dicyanophenyl)piperazin-1-yl]phenyl]propanoic acidIC5019.0 [1]
(2S)-3-[4-[4-(5-Acetylthiophen-2-yl)piperazin-1-yl]phenyl]-2-[[(2S)-1-(benzenesulfonyl)pyrrolidine-2-carbonyl]amino]propanoic acidIC5067.0 [1]
(2S)-2-[[(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carbonyl]amino]-3-[4-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]propanoic acidIC50124.0 [1]
(2S)-2-[[(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carbonyl]amino]-3-[4-[4-(cyclopropanecarbonyl)piperazin-1-yl]phenyl]propanoic acidIC5080.0 [1]
(2S)-2-[[(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carbonyl]amino]-3-[4-[4-(ethylcarbamoyl)piperazin-1-yl]phenyl]propanoic acidIC50200.0 [1]
(2S)-2-[[(4S)-3-(4-Methylphenyl)sulfonyl-1,3-thiazolidine-4-carbonyl]amino]-3-[4-(4-phenylpiperazin-1-yl)phenyl]propanoic acidIC50196.0 [1]
(2S)-2-[[(2R)-1-(3,5-Dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(4-phenylpiperazin-1-yl)phenyl]propanoic acidIC5028.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-(4-phenylpiperazin-1-yl)phenyl]propanoic acidIC501122.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Integrin alpha-4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/integrin-alpha-4-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 20). Quest Database™ Integrin alpha-4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/integrin-alpha-4-inhibitors-ic50-ki.
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