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Integrin alpha-3/beta-3 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Arg-gly-asp-serIC5013000.0 [1], 31000.0 [2]
3-(3-(Carbamoyl)benzamido)-3-(4-methoxyphenyl)propanoic acidIC500.8 [1], 17.0 [2]
3-(3-(Carbamoyl)benzamido)-3-(3,4-dimethoxyphenyl)propanoic acidIC500.7 [1], 11.6 [2]
3-(3-(Carbamoyl)benzamido)-3-phenylpropanoic acidIC501.0 [1], 25.0 [2]
3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propionylamino]-3-phenyl-propionic acid; hydrochlorideIC508.3 [1], 860.0 [2]
3-[[4-(2,3-Dihydro-1H-isoindol-5-ylamino)-4-oxobutanoyl]amino]-3-(4-propan-2-yloxyphenyl)propanoic acidIC506.0 [1], 105.0 [2]
3-[[4-(2,3-Dihydro-1H-isoindol-5-ylamino)-4-oxobutanoyl]amino]-3-(3,4-dimethoxyphenyl)propanoic acidIC509.0 [1], 890.0 [2]
3-(1,3-Benzodioxol-5-yl)-3-[[4-(2,3-dihydro-1H-isoindol-5-ylamino)-4-oxobutanoyl]amino]propanoic acidIC500.22 [1], 31.0 [2]
3-[[4-(2,3-Dihydro-1H-isoindol-5-ylamino)-4-oxobutanoyl]amino]-3-(4-methoxyphenyl)propanoic acidIC502.6 [1], 160.0 [2]
3-(4-Fluorophenyl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC501.0 [1], 8.9 [2]
3-(1,3-Benzodioxol-5-yl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC500.4 [1], 90.0 [2]
3-(4-Methylphenyl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC500.9 [1], 96.0 [2]
3-(4-Methoxyphenyl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC503.5 [1], 310.0 [2]
3-(3,4-Dimethoxyphenyl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC500.63 [1], 64.0 [2]
3-(4-Methoxyphenyl)-3-[[5-oxo-5-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)pentanoyl]amino]propanoic acidIC5018.0 [1], 4200.0 [2]
3-(3,4-Dimethoxyphenyl)-3-[[5-oxo-5-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)pentanoyl]amino]propanoic acidIC505.0 [1], 127.0 [2]
3-(1,3-Benzodioxol-5-yl)-3-[[5-oxo-5-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)pentanoyl]amino]propanoic acidIC500.78 [1], 53.0 [2]
3-[[4-Oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC501.21 [1], 30.01 [2]
3-[[4-Oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]-3-phenylpropanoic acidIC501.01 [1], 13.01 [2]
3-(3-Fluorophenyl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC501100.0 [1], 10000.0 [2]
3-(2-Fluorophenyl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC505.0 [1], 570.0 [2]
3-(4-Chlorophenyl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC5065.0 [1], 2000.0 [2]
3-[[4-Oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]-3-(4-propan-2-yloxyphenyl)propanoic acidIC5087.0 [1]
3-(4-Ethoxy-3-methoxyphenyl)-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC50510.0 [1]
3-Naphthalen-1-yl-3-[[4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-7-ylamino)butanoyl]amino]propanoic acidIC505200.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Integrin alpha-3/beta-3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.22 Dec2024https://www.aatbio.com/data-sets/integrin-alpha-3-beta-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 22). Quest Database™ Integrin alpha-3/beta-3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/integrin-alpha-3-beta-3-inhibitors-ic50-ki.
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