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Insulin-like growth factor binding protein 3 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi5.6 [1]
1-(1,3-Benzodioxole-5-ylcarbonyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi70.0 [1]
1-(3,4-Dihydroxybenzoyl)isoquinoline-3,6,7-triolKi28.0 [1]
1-(3,4-Dihydroxybenzyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi7.5 [1]
1-(3-Hydroxy-4-methoxy-benzoyl)-6,7-dimethoxy-isoquinoline-3-carboxylic AcidKi10000.0 [1]
1-(3,4-Dihydroxybenzyl)isoquinoline-3,6,7-triolKi29.0 [1]
6,7-Dimethoxy-1-(3,4-dimethoxybenzoyl)isoquinoline-3-olKi10000.0 [1]
7-Hydroxy-1-(3-hydroxy-4-methoxy-benzoyl)-6-methoxy-isoquinoline-3-carboxylic AcidKi320.0 [1]
6,7-Dimethoxy-1-(3,4-dimethoxybenzoyl)isoquinoline-3-carboxylic acid ethyl esterKi10000.0 [1]
1-(3,4-Dihydroxybenzoyl)isoquinoline-6,7-diolKi58.0 [1]
1-[3-Fluoro-4-(3,5-dichlorophenoxy)benzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi9.0 [1]
6,7-Dihydroxy-1-(1-naphthylcarbonyl)isoquinoline-3-carboxylic acidKi27.0 [1]
6,7-Dimethoxy-1-(3,4-dihydroxybenzoyl)isoquinoline-3-carboxylic acidKi10000.0 [1]
8-Bromo-6-methoxy-7-hydroxy-1-(3,4-dihydroxybenzoyl)isoquinoline-3-carboxylic acidKi140.0 [1]
6,7-Dihydroxy-1-(2,4-dichlorobenzoyl)isoquinoline-3-carboxylic acidKi44.0 [1]
5-Bromo-7-methoxy-6-hydroxy-1-(3,4-dihydroxybenzoyl)isoquinoline-3-carboxylic acidKi70.0 [1]
4-(3,4-Dihydroxybenzyl)-6,7-dihydroxy-2-quinolinecarboxylic acidKi8.0 [1]
6,7-Dihydroxy-1-(2-naphthylcarbonyl)isoquinoline-3-carboxylic acidKi13.0 [1]
1-(3-Fluoro-4-p-tolyloxy-benzoyl)-6,7-dihydroxy-isoquinoline-3-carboxylic acidKi9.4 [1]
1-[4-(Trifluoromethyl)benzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi38.0 [1]
1-[3-Fluoro-4-[4-(trifluoromethyl)phenoxy]benzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi32.0 [1]
1-(3,4-Dichlorobenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi29.0 [1]
1-(4-Aminobenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi130.0 [1]
6-Amino-1-(3,4-dihydroxy-benzoyl)-7-hydroxy-isoquinoline-3-carboxylic acidKi60.0 [1]
1-[4-(2-Ethylhexylamino)-3-fluorobenzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi62.0 [1]
1-[4-(4-Chlorophenyl)sulfanyl-3-fluorobenzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi31.0 [1]
1-[3-Fluoro-4-(4-phenylphenoxy)benzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi32.0 [1]
1-[4-(3,4-Dichlorophenoxy)-3-fluorobenzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi12.0 [1]
1-[4-(4-Chlorophenoxy)-3-fluorobenzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi20.0 [1]
1-[4-(Methylsulfonylamino)benzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi110.0 [1]
1-(4-Nitrobenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi32.0 [1]
1-(3-Fluorobenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi110.0 [1]
1-(alpha-Hydroxy-3-fluorobenzyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi24.0 [1]
1-(alpha-Hydroxy-2-chlorobenzyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi25.0 [1]
1-(alpha-Hydroxy-2,4,6-trimethylbenzyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi11.0 [1]
1-(3,4-Difluorobenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi51.0 [1]
1-(alpha-Hydroxy-4-phenoxybenzyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi32.0 [1]
1-[3-Fluoro-4-(3-chlorophenoxy)benzoyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi11.0 [1]
1-[alpha-Hydroxy-4-(trifluoromethyl)benzyl]-6,7-dihydroxyisoquinoline-3-carboxylic acidKi18.0 [1]
1-(2,4,6-Trimethylbenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi100.0 [1]
1-(2-Chlorobenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi110.0 [1]
1-(1,3-Benzodioxole-5-ylmethyl)-6,7-dihydroxyisoquinoline-3-carboxylic acidKi72.0 [1]
6-Amino-1-(1,3-benzodioxole-5-carbonyl)-7-hydroxyisoquinoline-3-carboxylic acidKi850.0 [1]
1-(1,3-Benzodioxole-5-carbonyl)-7-hydroxy-6-(methanesulfonamido)isoquinoline-3-carboxylic acidKi10000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Insulin-like growth factor binding protein 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/insulin-like-growth-factor-binding-protein-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Insulin-like growth factor binding protein 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/insulin-like-growth-factor-binding-protein-3-inhibitors-ic50-ki.
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