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Induced myeloid leukemia cell differentiation protein Mcl-1/Bcl-2-like protein 11 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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Marinopyrrole AIC508900.0 [1]
(4-Chloro-2-hydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC506500.0 [1]
[4,5-Dichloro-3-[2,3-dichloro-5-(5-fluoro-2-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrol-2-yl]-(2-hydroxyphenyl)methanoneIC508900.0 [1]
2-[4-[1-[2-[4-(Carboxymethylsulfanyl)-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-3-hydroxyphenyl]sulfanylacetic acidIC506100.0 [1]
[4,5-Dichloro-3-[2,3-dichloro-5-(2-fluoro-6-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrol-2-yl]-(2-hydroxyphenyl)methanoneIC5013100.0 [1]
(4-Chloro-2-methoxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-methoxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC508000.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(1-phenyltriazol-4-yl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-(1-phenyltriazol-4-yl)phenyl]methanoneIC501500.0 [1]
[4-(1-Cyclohexyltriazol-4-yl)-2-hydroxyphenyl]-[4,5-dichloro-1-[4,5-dichloro-2-[4-(1-cyclohexyltriazol-4-yl)-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC501400.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethenyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethenyl-2-hydroxyphenyl)methanoneIC503700.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethynyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethynyl-2-hydroxyphenyl)methanoneIC503900.0 [1]
Ethyl 2-[4-[2-chloro-4-[4,5-dichloro-1-[4,5-dichloro-2-[5-chloro-4-[1-(2-ethoxy-2-oxoethyl)triazol-4-yl]-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-5-hydroxyphenyl]triazol-1-yl]acetateIC507800.0 [1]
[1-[2-[4-(1-Benzyltriazol-4-yl)-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrol-2-yl]-[4-(1-benzyltriazol-4-yl)-2-hydroxyphenyl]methanoneIC503300.0 [1]
2-[4-[4-[1-[2-[4-[1-(Carboxymethyl)triazol-4-yl]-5-chloro-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-2-chloro-5-hydroxyphenyl]triazol-1-yl]acetic acidIC505200.0 [1]
Ethyl 2-[4-[4-[4,5-dichloro-1-[4,5-dichloro-2-[4-[1-(2-ethoxy-2-oxoethyl)triazol-4-yl]-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetateIC5018400.0 [1]
2-[4-[4-[1-[2-[4-[1-(Carboxymethyl)triazol-4-yl]-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetic acidIC5016500.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethyl-2-hydroxyphenyl)methanoneIC502100.0 [1]
[4-[4,5-Dichloro-3-[2,3-dichloro-5-(2-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrole-2-carbonyl]-3-hydroxyphenyl] trifluoromethanesulfonateIC501000.0 [1]
Ethyl 2-[4-[4,5-dichloro-1-[4,5-dichloro-2-[4-(2-ethoxy-2-oxoethyl)sulfanyl-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]sulfanylacetateIC501800.0 [1]
[1-[2-(4-Benzylsulfanyl-2-hydroxybenzoyl)-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrol-2-yl]-(4-benzylsulfanyl-2-hydroxyphenyl)methanoneIC50700.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-[(4-methoxyphenyl)methylsulfanyl]benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-[(4-methoxyphenyl)methylsulfanyl]phenyl]methanoneIC50700.0 [1]
[4-[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxy-4-phosphonobenzoyl)-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]phosphonic acidIC5010900.0 [1]
Tert-butyl 2-[4-[2-chloro-4-[4,5-dichloro-1-[4,5-dichloro-2-[5-chloro-2-hydroxy-4-[1-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]triazol-4-yl]benzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-5-hydroxyphenyl]triazol-1-yl]acetateIC501600.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(1-octyltriazol-4-yl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[4-(1-heptyltriazol-4-yl)-2-hydroxyphenyl]methanoneIC50600.0 [1]
Tert-butyl 2-[4-[4-[4,5-dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-[1-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]triazol-4-yl]benzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetateIC505100.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(2-methoxybenzoyl)-1-methylpyrrol-3-yl]pyrrol-2-yl]-(2-methoxyphenyl)methanoneIC5015500.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1-methylpyrrol-3-yl]pyrrol-2-yl]-(2-hydroxyphenyl)methanoneIC50100000.0 [1]
Marinopyrrole DIC503900.0 [1]
[8a-(Methoxymethoxymethyl)-3-methyl-6-[2-methyl-1-(2-methylprop-2-enylamino)-1-oxopropan-2-yl]-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] N-(3-chlorophenyl)carbamateIC508300.0 [1]
Benzyl 2-[(2S,4aR,5S,8aR)-4a-(methoxymethoxymethyl)-7-methyl-5-phenylmethoxy-2,5,6,8a-tetrahydro-1H-naphthalen-2-yl]-2-methylpropanoateIC5013100.0 [1]
[(1S,4Ar,6S,8aR)-6-[1-[(4-bromophenyl)methylamino]-2-methyl-1-oxopropan-2-yl]-8a-(methoxymethoxymethyl)-3-methyl-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] N-cyclohexylcarbamateIC5017000.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-fluoro-2-hydroxyphenyl)methanoneIC509600.0 [1]
(3-Chloro-2-hydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC504100.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(trifluoromethyl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-(trifluoromethyl)phenyl]methanoneIC508100.0 [1]
(5-Chloro-2,4-dihydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(5-chloro-2,4-dihydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC5010700.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(2,4-dihydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(2,4-dihydroxyphenyl)methanoneIC5039500.0 [1]
(5-Chloro-2-hydroxy-4-methylphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(5-chloro-2-hydroxy-4-methylbenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC502600.0 [1]
Items per page: 1 - 10 of 36
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References

This online tool may be cited as follows

MLA

"Quest Database™ Induced myeloid leukemia cell differentiation protein Mcl-1/Bcl-2-like protein 11 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/induced-myeloid-leukemia-cell-differentiation-protein-mcl-1-bcl-2-like-protein-11-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Induced myeloid leukemia cell differentiation protein Mcl-1/Bcl-2-like protein 11 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/induced-myeloid-leukemia-cell-differentiation-protein-mcl-1-bcl-2-like-protein-11-inhibitors-ic50-ki.
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