Indolethylamine N-methyltransferase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[4-(1H-indol-3-yl)butyl]-methylsulfanium;perchlorate	IC50	38000.0 [1]
	[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[4-(1H-indol-3-yl)butyl]-methylsulfanium;perchlorate	Ki	12000.0 [1]
	[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[3-(1H-indol-3-yl)propyl]-methylsulfanium	IC50	125000.0 [1]
	[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[3-(1H-indol-3-yl)propyl]-methylsulfanium	Ki	44400.0 [1]
	S-Adenosyl-L-homocysteine	Ki	2000.0 [1]
	5'-Deoxy-5'-methylthioadenosine	Ki	700000.0 [1]
	1,8-Diazabicyclo[5.4.0]undec-7-ene	IC50	25700.0 [1]
	3,4-Dihydro-2H-pyrrol-5-amine hydrochloride	IC50	8300000.0 [1]
	(2R,3R,4S,5S)-2-(6-Aminopurin-9-yl)-5-[3-(1H-indol-3-yl)propylsulfanylmethyl]oxolane-3,4-diol	IC50	1000000.0 [1]
	(2R,3R,4S,5S)-2-(6-Aminopurin-9-yl)-5-[4-(1H-indol-3-yl)butylsulfanylmethyl]oxolane-3,4-diol	IC50	1000000.0 [1]
	3-Methyl-N-[2-[(3-methyl-1,3-thiazolidin-2-ylidene)amino]ethyl]-1,3-thiazolidin-2-imine;dihydrochloride	IC50	75100.0 [1]
	3-Ethyl-1,3-thiazinan-2-imine;hydrobromide	IC50	9900.0 [1]
	N-Methyl-4,5-dihydro-1,3-thiazol-2-amine hydrochloride	IC50	15200.0 [1]
	N-Methylpyrrolidin-2-imine;hydroiodide	IC50	4425000.0 [1]
	3H-Pyrrolo[1,2-a][1,3]diazepine, 2,4,5,7,8,9-hexahydro-	IC50	852000.0 [1]
	(E)-But-2-enedioic acid;3,8-dihydro-2H-imidazo[2,1-c][1,4]thiazine	IC50	35000.0 [1]
	3-Methyl-1,3-thiazolidin-2-imine Hydroiodide	IC50	2200.0 [1]
	3-Methyl-1,3-thiazol-2(3H)-imine hydroiodide	IC50	6700.0 [1]
	2-Amino-4-[3-(1H-indol-3-yl)propylsulfanyl]butanoic acid	IC50	1000000.0 [1]
	2-Amino-4-[4-(1H-indol-3-yl)butylsulfanyl]butanoic acid	IC50	1000000.0 [1]
	1-Methylpyridin-4-imine;hydroiodide	IC50	63800.0 [1]
	(3-Amino-3-carboxypropyl)-[3-(1H-indol-3-yl)propyl]-methylsulfanium;perchlorate	IC50	1000000.0 [1]
	(3-Amino-3-carboxypropyl)-[4-(1H-indol-3-yl)butyl]-methylsulfanium;perchlorate	IC50	560000.0 [1]
	3,7-Dihydro-2H-imidazo[2,1-b][1,3]thiazine;oxalic acid	IC50	24500.0 [1]
	(Z)-But-2-enedioic acid;2-imino-1,3-thiazolidin-3-amine	IC50	46800.0 [1]
	(E)-But-2-enedioic acid;2,3,5,6,7,8-hexahydroimidazo[1,2-a]pyridine	IC50	800.0 [1]
	(E)-But-2-enedioic acid;3,5,6,8-tetrahydro-2H-imidazo[2,1-c][1,4]thiazine	IC50	6000.0 [1]
	(E)-But-2-enedioic acid;3-ethyl-1,3-thiazolidin-2-imine	IC50	2600.0 [1]
	1-Methylpyrrolidin-2-imine;hydroiodide	IC50	4300.0 [1]
	(E)-But-2-enedioic acid;2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidine	IC50	13400.0 [1]
	(E)-But-2-enedioic acid;3,4,6,7,8,9-hexahydro-2H-pyrido[1,2-a]pyrimidine	IC50	3300.0 [1]
	(E)-But-2-enedioic acid;3,5,6,7-tetrahydro-2H-pyrrolo[1,2-a]imidazole	IC50	1000.0 [1]
	1-Ethylpyrrolidin-2-imine;oxalic acid	IC50	2800.0 [1]
	1-Pentylpyrrolidin-2-imine;hydrobromide	IC50	106000.0 [1]
	4-Methylthiomorpholin-3-imine;hydrate;hydrochloride	IC50	32300.0 [1]
	4-Methyl-1,4-thiazin-3-imine;hydrobromide	IC50	12700.0 [1]
	3-Methyl-6H-1,3-thiazin-2-imine;hydrate;hydrochloride	IC50	4000.0 [1]
	1-Methylpyridin-2-imine;hydrochloride	IC50	15000.0 [1]
	1-Prop-2-enylpyridin-2-imine;hydrobromide	IC50	11600.0 [1]
	(E)-But-2-enedioic acid;1-methyl-2,3-dihydropyridin-6-imine	IC50	7900.0 [1]
	3-Methylamino-thiazolidin-2-ylideneamine	IC50	6400.0 [1]
	3-Methyl-[1,3]thiazinan-2-ylideneamine	IC50	3700.0 [1]
	[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[4-(1H-indol-3-yl)butyl]-methylsulfanium	Ki	12000.0 [1]
	3,5,6,8-Tetrahydro-2H-imidazo[2,1-c][1,4]thiazine 7-oxide	IC50	18800.0 [1]
	3-Methyl-5-trifluoromethyl-3H-thiazol-2-ylideneamine	IC50	86600.0 [1]
	N,2-Dimethyl-1,2-thiazol-3-imine	IC50	19200.0 [1]
	N,2-Dimethyl-1,2,5-thiadiazol-3-imine	IC50	12000.0 [1]
	2,3-Dimethyl-1,2-thiazol-5-imine	IC50	45410.0 [1]
	2-Methyl-1,2-thiazol-3-imine	IC50	3283000.0 [1]
	2-Methyl-1,2-thiazol-5-imine	IC50	21900.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 50 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Indolethylamine N-methyltransferase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/indolethylamine-n-methyltransferase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 22). Quest Database™ Indolethylamine N-methyltransferase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/indolethylamine-n-methyltransferase-inhibitors-ic50-ki.
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