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Indoleamine 2,3-dioxygenase 2 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1-Methyl-L-tryptophanIC5056900.0 [1], 82500.0 [2]
1-Methyl-L-tryptophanKi300000.0 [1], 425000.0 [2]
IndoximodIC50148900.0 [1], 262700.0 [2]
IndoximodKi3300000.0 [1]
Indolo[2,1-b]quinazoline-6,12-dioneIC505000.0 [1], 17300.0 [2]
Indolo[2,1-b]quinazoline-6,12-dioneKi15200.0 [1]
8-Fluoroindolo[2,1-b]quinazoline-6,12-dioneIC501200.0 [1], 7600.0 [2]
8-Fluoroindolo[2,1-b]quinazoline-6,12-dioneKi3500.0 [1]
8-Bromoindolo[2,1-b]quinazoline-6,12-dioneIC503200.0 [1], 8300.0 [2]
8-Bromoindolo[2,1-b]quinazoline-6,12-dioneKi5600.0 [1]
8-Nitroindolo[2,1-b]quinazoline-6,12-dioneIC50450.0 [1], 1800.0 [2]
8-Nitroindolo[2,1-b]quinazoline-6,12-dioneKi970.0 [1]
8-Methylindolo[2,1-b]quinazoline-6,12-dioneIC5021800.0 [1], 32000.0 [2]
8-Methylindolo[2,1-b]quinazoline-6,12-dioneKi34600.0 [1]
9-Chloroindolo[2,1-b]quinazoline-6,12-dioneIC5018400.0 [1], 67900.0 [2]
9-Chloroindolo[2,1-b]quinazoline-6,12-dioneKi39500.0 [1]
2,8-Difluoroindolo[2,1-b]quinazoline-6,12-dioneIC508200.0 [1], 21700.0 [2]
2,8-Difluoroindolo[2,1-b]quinazoline-6,12-dioneKi13200.0 [1]
2-Fluoroindolo[2,1-b]quinazoline-6,12-dioneIC5037800.0 [1], 56800.0 [2]
2-Fluoroindolo[2,1-b]quinazoline-6,12-dioneKi105100.0 [1]
7-Chloroindolo[2,1-b]quinazoline-6,12-dioneIC5019500.0 [1], 43400.0 [2]
7-Chloroindolo[2,1-b]quinazoline-6,12-dioneKi24600.0 [1]
N-(1,3-Benzodioxol-5-yl)-2-[[5-(4-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl]sulfanyl]acetamideIC50250000.0 [1]
3-N-(3,4-Difluorophenyl)-7-pyridin-4-ylfuro[2,3-c]pyridine-2,3-diamineIC501000.0 [1]
3-N-(3-Chloro-4-fluorophenyl)furo[2,3-c]pyridine-2,3-diamineIC501000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Indoleamine 2,3-dioxygenase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/indoleamine-2-3-dioxygenase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Indoleamine 2,3-dioxygenase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/indoleamine-2-3-dioxygenase-2-inhibitors-ic50-ki.
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