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Immunoglobulin epsilon Fc receptor Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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BatimastatIC50100.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamideIC501900.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(naphthalen-2-ylmethyl)butanediamideIC501000.0 [1]
(2R)-2-Benzyl-N-[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxybutanediamideIC505000.0 [1]
(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(phenylsulfanylmethyl)butanediamideIC5040.0 [1]
Methylamino-phenylalanyl-leucyl-hydroxamic acidIC501000.0 [1]
(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(phenacylsulfanylmethyl)butanediamideIC5016.0 [1]
(2S,3R)-N-Hydroxy-2-[[(2E)-2-hydroxyimino-2-phenylethyl]sulfanylmethyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamideIC5012.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-(1-benzothiophen-2-ylmethyl)-N',3-dihydroxybutanediamideIC5020.0 [1]
(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-phenylbutanediamideIC501600.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N',3-dihydroxy-2-(naphthalen-2-ylmethyl)butanediamideIC50600.0 [1]
(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-(naphthalen-2-ylmethyl)butanediamideIC5020.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-2-(cyclopentylmethyl)-N'-hydroxybutanediamideIC50200.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-2-(cyclohexylmethyl)-N'-hydroxybutanediamideIC503700.0 [1]
(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamideIC5020000.0 [1]
(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-2-cyclohexyl-N'-hydroxybutanediamideIC505000.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-propan-2-ylsulfanylbutanediamideIC508000.0 [1]
(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(4-phenylphenyl)butanediamideIC5020000.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(propan-2-ylsulfanylmethyl)butanediamideIC5020000.0 [1]
(2R)-2-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-1-N-hydroxybutane-1,2,4-tricarboxamideIC5020000.0 [1]
(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-naphthalen-1-ylbutanediamideIC5020000.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-methylbutanediamideIC5020000.0 [1]
(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-2-[(dimethylamino)methyl]-N'-hydroxybutanediamideIC5020000.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N',2-dihydroxybutanediamideIC5020000.0 [1]
(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-phenylethyl)butanediamideIC505000.0 [1]
N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxybutanediamideIC5020000.0 [1]
(2S)-2-Benzyl-N-[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxybutanediamideIC5020000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-[(6-fluoronaphthalen-2-yl)methyl]-N',3-dihydroxybutanediamideIC50220.0 [1]
(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-(quinolin-6-ylmethyl)butanediamideIC501000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-[(7-fluoronaphthalen-2-yl)methyl]-N',3-dihydroxybutanediamideIC50100.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-(1,3-benzothiazol-2-ylmethyl)-N',3-dihydroxybutanediamideIC50320.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N',3-dihydroxy-2-[(7-hydroxynaphthalen-2-yl)methyl]butanediamideIC50760.0 [1]
(2S,3R)-3-(1-Benzofuran-2-ylmethyl)-N,2-dihydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]butanediamideIC50100.0 [1]
(2S,3R)-3-(1-Benzothiophen-3-ylmethyl)-N,2-dihydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]butanediamideIC501000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-[(3-chloro-1-benzothiophen-2-yl)methyl]-N',3-dihydroxybutanediamideIC5010000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N',3-dihydroxy-2-[(7-phenylmethoxynaphthalen-2-yl)methyl]butanediamideIC5020000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-2-[(6,7-difluoronaphthalen-2-yl)methyl]-N',3-dihydroxybutanediamideIC501000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-(quinolin-3-ylmethyl)butanediamideIC5020.0 [1]
(2R,3S)-N-[(2S)-3,3-Dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(5,6,7,8-tetrahydronaphthalen-2-ylmethyl)butanediamideIC5010000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-2-[(7-fluoronaphthalen-2-yl)methyl]-N',3-dihydroxybutanediamideIC5080.0 [1]
(2S,3R)-N,2-Dihydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(naphthalen-2-ylmethyl)butanediamideIC50400.0 [1]
(2S,3R)-N,2-Dihydroxy-3-[(7-methoxy-1-benzofuran-2-yl)methyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]butanediamideIC5020000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(phenacylsulfanylmethyl)butanediamideIC5020.0 [1]
(2S,3R)-2-(Benzylsulfanylmethyl)-N-hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamideIC5030.0 [1]
(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-[(4-nitrophenyl)sulfanylmethyl]butanediamideIC50100.0 [1]
2-[(2S,3R)-2-(Hydroxycarbamoyl)-5-methyl-3-[[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]hexyl]sulfanylbenzoic acidIC503700.0 [1]
Methyl 2-[(2S,3R)-2-(hydroxycarbamoyl)-5-methyl-3-[[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]hexyl]sulfanylbenzoateIC50100.0 [1]
Methyl 4-[(2S,3R)-2-(hydroxycarbamoyl)-5-methyl-3-[[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]hexyl]sulfanylbenzoateIC5050.0 [1]
(2S,3R)-N-Hydroxy-2-[[(2E)-2-hydroxyimino-2-(4-phenylphenyl)ethyl]sulfanylmethyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamideIC50130.0 [1]
(2S,3R)-N-Hydroxy-2-[(4-hydroxyphenyl)sulfanylmethyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamideIC5040.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(thiophen-2-ylsulfanylmethyl)butanediamideIC5030.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-benzyl-N'-hydroxy-3-(thiophen-2-ylsulfanylmethyl)butanediamideIC50160.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-3-[[(2E)-2-hydroxyimino-2-phenylethyl]sulfanylmethyl]-2-(2-methylpropyl)butanediamideIC50100.0 [1]
(2S,3R)-N-Hydroxy-2-[[(2E)-2-methoxyimino-2-phenylethyl]sulfanylmethyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamideIC5080.0 [1]
(2R)-2-Benzyl-N'-hydroxy-N-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]butanediamideIC5020000.0 [1]
2-[(2S,3R)-3-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2-(hydroxycarbamoyl)-5-methylhexyl]sulfanylacetic acidIC501000.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(sulfanylmethyl)butanediamideIC50130.0 [1]
(2R)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamideIC503000.0 [1]
S-[(2S,3R)-3-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2-(hydroxycarbamoyl)-5-methylhexyl] ethanethioateIC501000.0 [1]
Methyl 2-[(2S,3R)-3-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2-(hydroxycarbamoyl)-5-methylhexyl]sulfanylacetateIC5013.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-3-(cyanomethylsulfanylmethyl)-N'-hydroxy-2-(2-methylpropyl)butanediamideIC50100.0 [1]
(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-[[2-oxo-2-(4-phenylphenyl)ethyl]sulfanylmethyl]butanediamideIC50380.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-3-[[(2E)-2-(4-chlorophenyl)-2-hydroxyiminoethyl]sulfanylmethyl]-N'-hydroxy-2-(2-methylpropyl)butanediamideIC5060.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-benzyl-N'-hydroxy-3-[[(2Z)-2-methoxyimino-2-phenylethyl]sulfanylmethyl]butanediamideIC50100.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-benzyl-N'-hydroxy-3-[[(2Z)-2-hydroxyimino-2-phenylethyl]sulfanylmethyl]butanediamideIC50130.0 [1]
(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-benzyl-N'-hydroxy-3-(phenacylsulfanylmethyl)butanediamideIC50210.0 [1]
(2R,3S)-3-[(2-Amino-2-oxoethyl)sulfanylmethyl]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamideIC50100.0 [1]
(3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-[[(2S)-1,2,3,4-tetrahydronaphthalen-2-yl]methyl]butanediamideIC5070.0 [1]
(3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-[[(2R)-1,2,3,4-tetrahydronaphthalen-2-yl]methyl]butanediamideIC5070.0 [1]
(2R,3S)-N-[(2S)-3,3-Dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(naphthalen-2-ylmethyl)butanediamideIC50230.0 [1]
Items per page: 1 - 10 of 70
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References

This online tool may be cited as follows

MLA

"Quest Database™ Immunoglobulin epsilon Fc receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/immunoglobulin-epsilon-fc-receptor-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Immunoglobulin epsilon Fc receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/immunoglobulin-epsilon-fc-receptor-inhibitors-ic50-ki.
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