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IL15-IL15 receptor Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Ethyl 3-[8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanoylamino]benzoateIC50800.0 [1], 57000.0 [2]
CID 2821848IC5017300.0 [1], 9110000.0 [2]
N-(1-Adamantyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC501600.0 [1], 210000.0 [2]
N-(2,4-Dibromophenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC501500.0 [1], 92000.0 [2]
N-(2-Chloro-4-methylphenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC502300.0 [1], 76000.0 [2]
N-(2,4-Dichlorophenyl)-11-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]undecanamideIC503300.0 [1], 142000.0 [2]
N-(2,4-Dichlorophenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC501900.0 [1], 153000.0 [2]
N-(2-Hydroxy-4-methoxyphenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC501300.0 [1], 360000.0 [2]
N-(4-Azidophenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC501800.0 [1], 100000.0 [2]
N-(2,4-Difluorophenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC502300.0 [1], 110000.0 [2]
N-(1-Adamantyl)-11-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]undecanamideIC503800.0 [1], 124000.0 [2]
N-(2,4-Dimethoxyphenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC501100.0 [1], 205000.0 [2]
8-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-propan-2-yloxyphenyl)octanamideIC501100.0 [1], 93000.0 [2]
8-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-[4-(2-methylpropoxy)phenyl]octanamideIC504800.0 [1], 55000.0 [2]
N-(4-Methoxyphenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC503900.0 [1], 201000.0 [2]
8-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-propoxyphenyl)octanamideIC501600.0 [1], 40000.0 [2]
N-(2,4-Dichlorophenyl)-6-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]hexanamideIC504100.0 [1]
N-(1-Adamantyl)-2-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamideIC5030000000.0 [1]
N-(2,4-Dichlorophenyl)-4-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]butanamideIC509800.0 [1]
N-(2-Hydroxyphenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC5027000.0 [1]
11-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-naphthalen-1-ylundecanamideIC506600.0 [1]
N-(2,4-Dihydroxyphenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC5017000.0 [1]
N-(4-Iodophenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC501300.0 [1]
N-(2,4-Dibromophenyl)-2-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamideIC5030000.0 [1]
N-(4-Hydroxyphenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC5030000.0 [1]
N-(2,4-Dibromophenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfonyl]octanamideIC501400.0 [1]
N-(2,4-Dichlorophenyl)-N-methyl-2-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamideIC5030000.0 [1]
4-[[5-[[1-(1-Adamantyl)triazol-4-yl]methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]-2-methylphthalazin-1-oneIC5030000.0 [1]
N-(2,4-Dichlorophenyl)-N-methyl-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC5011900.0 [1]
(2,4-Dichlorophenyl) 8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanoateIC50800.0 [1]
(2,4-Dichlorophenyl) 11-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]undecanoateIC508700.0 [1]
4-[(5-Decylsulfanyl-4-methyl-1,2,4-triazol-3-yl)methyl]-2-methylphthalazin-1-oneIC507600.0 [1]
N-(2,4-Dichlorophenyl)-16-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]hexadecanamideIC507300.0 [1]
N-(4-Chlorophenyl)-11-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]undecanamideIC5020000.0 [1]
3-[8-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanoylamino]benzoic acidIC5030000.0 [1]
N-(2,4-Dichlorophenyl)-10-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]decanamideIC502300.0 [1]
2-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-propan-2-yloxyphenyl)acetamideIC5030000.0 [1]
N-(4-Chlorophenyl)-8-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]octanamideIC50800.0 [1]
8-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-naphthalen-1-yloctanamideIC501900.0 [1]
2-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-[4-(2-methylpropoxy)phenyl]acetamideIC5030000.0 [1]
N-(2-Chlorophenyl)-11-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]undecanamideIC5015000.0 [1]
2-[[4-Methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-propoxyphenyl)acetamideIC5030000.0 [1]
N-(2,4-Dichlorophenyl)-5-[4-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanylmethyl]triazol-1-yl]pentanamideIC5030000.0 [1]
Ethyl 2-[[2-[[4-methyl-5-[(3-methyl-4-oxophthalazin-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoateIC5030000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ IL15-IL15 receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/il15-il15-receptor-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ IL15-IL15 receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/il15-il15-receptor-inhibitors-ic50-ki.
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