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HSP60/HSP10 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
4-Methyl-N-[4-[6-[(4-methylphenyl)sulfonylamino]-1H-benzimidazol-2-yl]phenyl]benzenesulfonamideIC5089000.0 [1], 106000.0 [2]
N-[4-(1,3-Benzothiazol-2-ylsulfanyl)-3-chlorophenyl]-3,5-dibromo-2-hydroxybenzamideIC503600.0 [1], 4200.0 [2], 5500.0 [3]
4-Nitro-N-[4-[5-[(4-nitrophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5051000.0 [1], 65000.0 [2], 250000.0 [3]
4-Chloro-N-[4-[5-[(4-chlorophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5096000.0 [1], 250000.0 [2]
3-(Trifluoromethyl)-N-[4-[5-[[3-(trifluoromethyl)phenyl]sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5058000.0 [1], 100000.0 [2], 250000.0 [3]
EflornithineIC50100000.0 [1], 250000.0 [2]
PentamidineIC50100000.0 [1], 250000.0 [2]
NifurtimoxIC50100000.0 [1], 250000.0 [2]
8-[4-Methyl-3-[(5Z)-5-[(Z)-[5-[[2-methyl-5-[(4,6,8-trisulfo-2H-naphthalen-1-ylidene)carbamoyl]cyclohexa-2,4-dien-1-ylidene]carbamoyl]cyclohexa-2,4-dien-1-ylidene]carbamoyl]iminocyclohexa-1,3-diene-1-carbonyl]iminocyclohexa-1,4-diene-1-carbonyl]imino-7H-naphthalene-1,3,5-trisulfonic acidIC5011000.0 [1], 250000.0 [2]
N-[2,3-Bis(furan-2-yl)quinoxalin-6-yl]pyrrolidine-1-carboxamideIC5013000.0 [1], 250000.0 [2]
Methyl-carbamic acid 5,7-dibromo-2-oxo-benzo[1,3]oxathiol-6-yl esterIC501800.0 [1], 250000.0 [2]
N-(7-Acetyl-2,3-dihydro-1,4-benzodioxin-6-yl)-2-bromobenzamideIC50100000.0 [1], 250000.0 [2]
1-[2,3-Bis(furan-2-yl)quinoxalin-6-yl]-3-(2-hydroxyethyl)ureaIC5015000.0 [1], 250000.0 [2]
N-{4-[(2E)-3-(3-Nitrophenyl)prop-2-enoyl]phenyl}furan-2-carboxamideIC501600.0 [1], 250000.0 [2]
4-Chloro-3-nitro-1-(phenylmethyl)-2-quinolinoneIC502800.0 [1], 250000.0 [2]
4-[2-(4-Aminoanilino)-1,3-thiazol-4-yl]benzene-1,2-diolIC5010000.0 [1], 250000.0 [2]
1-[2,3-Bis(furan-2-yl)quinoxalin-6-yl]-3-methylureaIC507400.0 [1], 250000.0 [2]
3-[[4-[5-[(3-Carboxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]sulfamoyl]benzoic acidIC5081000.0 [1], 250000.0 [2]
2-Hydroxy-N-[4-[5-[(2-hydroxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5013000.0 [1], 33000.0 [2]
N-[4-[5-(2,1,3-Benzothiadiazol-4-ylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]-2,1,3-benzothiadiazole-4-sulfonamideIC5098000.0 [1], 152000.0 [2]
4-(Trifluoromethyl)-N-[4-[5-[[4-(trifluoromethyl)phenyl]sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5061000.0 [1], 250000.0 [2]
2-(Trifluoromethyl)-N-[4-[5-[[2-(trifluoromethyl)phenyl]sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
N-[4-[5-(Benzenesulfonamido)-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
4-Cyano-N-[4-[5-[(4-cyanophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5064000.0 [1], 250000.0 [2]
3-Chloro-N-[4-[5-[(3-chlorophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
3-Fluoro-N-[4-[5-[(3-fluorophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5068000.0 [1], 250000.0 [2]
N-[4-[5-(Methanesulfonamido)-1,3-benzoxazol-2-yl]phenyl]methanesulfonamideIC50100000.0 [1], 250000.0 [2]
3-Methyl-N-[4-[5-[(3-methylphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
3-Cyano-N-[4-[5-[(3-cyanophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5091000.0 [1], 250000.0 [2]
N-[4-[5-(Naphthalen-1-ylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]naphthalene-1-sulfonamideIC50100000.0 [1], 144000.0 [2]
Methyl 3-[[4-[5-[(3-methoxycarbonylphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]sulfamoyl]benzoateIC5095000.0 [1], 250000.0 [2]
N-[4-[5-(Benzylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]-1-phenylmethanesulfonamideIC50100000.0 [1], 250000.0 [2]
2-Fluoro-N-[4-[5-[(2-fluorophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5077000.0 [1], 250000.0 [2]
3-Methoxy-N-[4-[5-[(3-methoxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
2-[[4-[5-[(2-Carboxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]sulfamoyl]benzoic acidIC50100000.0 [1], 250000.0 [2]
2-Oxo-N-[4-[5-[(2-oxochromen-6-yl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]chromene-6-sulfonamideIC5070000.0 [1], 201000.0 [2]
3-Nitro-N-[4-[5-[(3-nitrophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5060000.0 [1], 250000.0 [2]
4-Fluoro-N-[4-[5-[(4-fluorophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
2-Cyano-N-[4-[5-[(2-cyanophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5086000.0 [1], 193000.0 [2]
1,1,1-Trifluoro-N-[4-[5-(trifluoromethylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]methanesulfonamideIC5097000.0 [1], 250000.0 [2]
Methyl 4-[[4-[5-[(4-methoxycarbonylphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]sulfamoyl]benzoateIC5087000.0 [1], 250000.0 [2]
2-Amino-N-[4-[5-[(2-aminophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
3-Bromo-N-[4-[5-[(3-bromophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
4-Amino-N-[4-[5-[(4-aminophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5068000.0 [1], 224000.0 [2]
2-Methyl-N-[4-[5-[(2-methylphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
4-Methoxy-N-[4-[5-[(4-methoxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
N-[4-[5-(2,1,3-Benzoxadiazol-4-ylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]-2,1,3-benzoxadiazole-4-sulfonamideIC5066000.0 [1], 212000.0 [2]
3-Hydroxy-N-[4-[5-[(3-hydroxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5019000.0 [1], 61000.0 [2]
N-[4-[5-(Propylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]propane-1-sulfonamideIC50100000.0 [1], 250000.0 [2]
2-Nitro-N-[4-[5-[(2-nitrophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5075000.0 [1], 194000.0 [2]
3-Amino-N-[4-[5-[(3-aminophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5087000.0 [1], 127000.0 [2]
2-Methoxy-N-[4-[5-[(2-methoxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
4-[[4-[5-[(4-Carboxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]sulfamoyl]benzoic acidIC50100000.0 [1], 250000.0 [2]
4-Bromo-N-[4-[5-[(4-bromophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
N-[4-[5-(Thiophen-2-ylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]thiophene-2-sulfonamideIC5057000.0 [1], 250000.0 [2]
N-[4-[5-(2,1,3-Benzothiadiazol-5-ylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]-2,1,3-benzothiadiazole-5-sulfonamideIC5062000.0 [1], 127000.0 [2]
Methyl 2-[[4-[5-[(2-methoxycarbonylphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]sulfamoyl]benzoateIC50100000.0 [1], 250000.0 [2]
4-Hydroxy-N-[4-[5-[(4-hydroxyphenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC5011000.0 [1], 59000.0 [2]
2-Chloro-N-[4-[5-[(2-chlorophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
2-Bromo-N-[4-[5-[(2-bromophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]benzenesulfonamideIC50100000.0 [1], 250000.0 [2]
N-[(E)-(8-Hydroxyquinolin-5-yl)methylideneamino]-4-methoxybenzamideIC50100000.0 [1], 250000.0 [2]
N-(4-Hydroxyphenyl)-3-[(5E)-5-(3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanamideIC5013000.0 [1], 250000.0 [2]
Methyl 4-{5-[(E)-(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}benzoateIC5016000.0 [1], 250000.0 [2]
(5Z)-5-[(3,4-Dihydroxyphenyl)methylidene]-3-(4-hydroxyphenyl)-2-sulfanylidene-1,3-thiazolidin-4-oneIC504900.0 [1], 250000.0 [2]
N-(3-Nitrophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamideIC50100000.0 [1], 250000.0 [2]
4-(4-Hydroxy-3-nitrophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-6-carboxylic acidIC503300.0 [1], 140000.0 [2]
2-Benzyl-N-(2-hydroxy-5-nitrophenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxamideIC5038000.0 [1], 250000.0 [2]
Quinoline-3-carboxamide, 1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-(4-pyridyl)-IC50100000.0 [1], 250000.0 [2]
[4-[(Z)-[5-Imino-2-(2-methylpropyl)-7-oxo-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-ylidene]methyl]-2-methoxyphenyl] 4-fluorobenzoateIC5026000.0 [1], 250000.0 [2]
(E)-1-(3,4-Dihydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-oneIC505200.0 [1], 250000.0 [2]
N-[4-[(E)-3-(Furan-2-yl)prop-2-enoyl]phenyl]thiophene-2-carboxamideIC508200.0 [1], 250000.0 [2]
2-(5-Amino-[1,3,4]thiadiazol-2-ylsulfanyl)-1-biphenyl-4-yl-ethanoneIC50100000.0 [1], 250000.0 [2]
N-[4-[6-(Naphthalen-2-ylsulfonylamino)-1H-benzimidazol-2-yl]phenyl]naphthalene-2-sulfonamideIC50100000.0 [1], 127000.0 [2]
N-[4-[5-(1,3-Benzothiazol-6-ylsulfonylamino)-1,3-benzoxazol-2-yl]phenyl]-1,3-benzothiazole-6-sulfonamideIC5049000.0 [1], 250000.0 [2]
VancomycinIC50100000.0 [1]
AmpicillinIC50100000.0 [1]
RifampicinIC50100000.0 [1]
ClosantelIC502500.0 [1]
RafoxanideIC502800.0 [1]
SalicylanilideIC50100000.0 [1]
BenzanilideIC50100000.0 [1]
3'-ChlorobenzanilideIC50100000.0 [1]
N-(3-Chlorophenyl)-2-hydroxybenzamideIC50100000.0 [1]
MetabromsalanIC5063000.0 [1]
N-(3-Chlorophenyl)-2-methoxybenzamideIC50100000.0 [1]
3,5-Dibromo-N-(3-chloro-phenyl)-2-hydroxy-benzamideIC5029000.0 [1]
5-Bromo-N-(3-chlorophenyl)-2-methoxybenzamideIC50100000.0 [1]
5-BromosalicylanilideIC50100000.0 [1]
3,5-Dibromo-N-phenylbenzamideIC50100000.0 [1]
5-Bromo-N-(3-chlorophenyl)-2-hydroxybenzamideIC50100000.0 [1]
Benzamide, N-(3-chlorophenyl)-3-bromo-IC50100000.0 [1]
2-Methoxy-N-phenylbenzamideIC50100000.0 [1]
3,5-Dibromo-N-(3-chlorophenyl)benzamideIC50100000.0 [1]
3,5-Dibromo-2-methoxy-N-phenylbenzamideIC50100000.0 [1]
5-Chloro-N-[2-[4-[(4-chloro-3-nitrophenyl)sulfonylamino]phenyl]-1,3-benzoxazol-5-yl]thiophene-2-sulfonamideIC502100.0 [1]
5-Chloro-N-[4-[5-[(3,4-dichlorophenyl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]thiophene-2-sulfonamideIC504700.0 [1]
N-[4-[5-[(5-Chlorothiophen-2-yl)sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]-2,1,3-benzoxadiazole-4-sulfonamideIC5011000.0 [1]
5-Chloro-N-[4-[5-[[4-chloro-3-(trifluoromethyl)phenyl]sulfonylamino]-1,3-benzoxazol-2-yl]phenyl]thiophene-2-sulfonamideIC502400.0 [1]
5-Chloro-N-[2-[4-[[4-chloro-3-(trifluoromethyl)phenyl]sulfonylamino]phenyl]-1,3-benzoxazol-5-yl]thiophene-2-sulfonamideIC506100.0 [1]
5-Chloro-N-[2-[4-[[3-(trifluoromethyl)phenyl]sulfonylamino]phenyl]-1,3-benzoxazol-5-yl]thiophene-2-sulfonamideIC504500.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ HSP60/HSP10 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 19 Feb. 2025, https://www.aatbio.com/data-sets/hsp60-hsp10-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 19). Quest Database™ HSP60/HSP10 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/hsp60-hsp10-inhibitors-ic50-ki.
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