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Homeodomain-interacting protein kinase 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
StaurosporineIC502639.0 [1]
DoramapimodIC5030000.0 [1]
Bisindolylmaleimide IX mesylateIC500.37 [1]
N-(Pyridin-4-yl)-3-[1-(4-chlorobenzyl)indol-3-yl]-propanamideIC50100000.0 [1]
1-[5-Amino-4-(3,4-dichlorophenyl)-3-methylpyrazol-1-yl]ethanoneIC50100000.0 [1]
3-[1-[(4-Chlorophenyl)methyl]indol-3-yl]-N-(4-nitrophenyl)propanamideIC50100000.0 [1]
1-[5-Tert-butyl-3-[4-[2-(dimethylamino)ethyl]-5-oxo-1,4-diazepane-1-carbonyl]thiophen-2-yl]-3-(2,3-dichlorophenyl)ureaIC5030000.0 [1]
N-[2-[2-Aminoethyl(methyl)amino]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamideIC5040.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC5010000.0 [1]
TilfrinibIC5010000.0 [1]
1-Tert-butyl-3-[7-(4-hydroxy-3-methoxyphenyl)-1,5-naphthyridin-2-yl]ureaIC50100000.0 [1]
4-(2-Chloro-4-fluorophenyl)-8-(2,6-dichlorophenyl)-7-oxido-1,7-naphthyridin-7-iumIC5010000.0 [1]
N-[(4-Methoxyphenyl)methyl]-[1]benzofuro[2,3-b]pyridin-4-amineKi1000000.0 [1]
1-Benzyl-3-[7-(1-methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]ureaIC50100000.0 [1]
1-Tert-butyl-3-[7-(1-methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]ureaIC50100000.0 [1]
1-[7-(1-Methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]-3-phenylureaIC50100000.0 [1]
1-Ethyl-3-[7-(4-methoxyphenyl)-1,5-naphthyridin-2-yl]ureaIC50100000.0 [1]
1-[7-(3,4-Dimethoxyphenyl)-1,5-naphthyridin-2-yl]-3-ethylureaIC5013600.0 [1]
1-Tert-butyl-3-[7-(3,4-dimethoxyphenyl)-1,5-naphthyridin-2-yl]ureaIC50100000.0 [1]
1-[7-(1-Methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]-3-(2-phenylethyl)ureaIC50100000.0 [1]
1-(4-Methoxyphenyl)-3-(3-phenylpyrido[3,4-b]pyrazin-8-yl)ureaIC5020430.0 [1]
N-(3-Chloro-4-fluorophenyl)-3-phenylpyrido[3,4-b]pyrazin-8-amineIC50100000.0 [1]
3-Phenyl-N-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-8-amineIC502730.0 [1]
N-Phenyl-3-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-8-amineIC50100000.0 [1]
N-(3-Methoxyphenyl)-3-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-8-amineIC50100000.0 [1]
1-(3-Methoxyphenyl)-3-(2-phenylpyrido[3,4-b]pyrazin-5-yl)ureaIC50100000.0 [1]
1-Ethyl-3-(2-phenylpyrido[3,4-b]pyrazin-5-yl)ureaIC50100000.0 [1]
N-(3-Ethynylphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amineIC50100000.0 [1]
3-Phenyl-N-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-7-amineIC50100000.0 [1]
N-(2-Methoxyphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amineIC50100000.0 [1]
N-(4-Methoxyphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amineIC50100000.0 [1]
2-Phenyl-N-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-5-amineIC50922.0 [1]
N-(4-Morpholin-4-ylphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amineIC50100000.0 [1]
2-(4-Methoxyphenyl)-N-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-5-amineIC507250.0 [1]
2-(4-Methoxyphenyl)-N-(4-morpholin-4-ylphenyl)pyrido[3,4-b]pyrazin-5-amineIC50100000.0 [1]
2-Phenyl-N-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-7-amineIC5030510.0 [1]
N-(4-Morpholin-4-ylphenyl)-2-phenylpyrido[3,4-b]pyrazin-7-amineIC50100000.0 [1]
1-(3-Phenylpyrido[3,4-b]pyrazin-8-yl)-3-prop-2-enylureaIC50100000.0 [1]
N-(3-Methoxyphenyl)-2-phenylpyrido[3,4-b]pyrazin-7-amineIC50100000.0 [1]
N-(3-Methoxyphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amineIC50100000.0 [1]
1-(3-Methoxyphenyl)-3-(3-phenylpyrido[3,4-b]pyrazin-8-yl)ureaIC50100000.0 [1]
2-Phenyl-N-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-8-amineIC502590.0 [1]
N-(4-Morpholin-4-ylphenyl)-2-phenylpyrido[3,4-b]pyrazin-8-amineIC508150.0 [1]
2-(4-Methoxyphenyl)-N-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-8-amineIC503210.0 [1]
2-(4-Methoxyphenyl)-N-(4-morpholin-4-ylphenyl)pyrido[3,4-b]pyrazin-8-amineIC504020.0 [1]
N-(2,5-Dimethoxyphenyl)-2-(4-methoxyphenyl)pyrido[3,4-b]pyrazin-8-amineIC5013100.0 [1]
N-Phenyl-2-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-8-amineIC5011850.0 [1]
N-(3-Methoxyphenyl)-2-(4-piperidin-1-ylphenyl)pyrido[3,4-b]pyrazin-8-amineIC5012650.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Homeodomain-interacting protein kinase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/homeodomain-interacting-protein-kinase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Homeodomain-interacting protein kinase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/homeodomain-interacting-protein-kinase-1-inhibitors-ic50-ki.
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