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Histone deacetylase 9 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
VorinostatIC5010000.0 [1]
VorinostatKi49.0 [1], 65.0 [2], 2000.0 [3]
Trichostatin AIC5038.1 [1]
Trichostatin AKi800.0 [1]
PanobinostatIC50887.8 [1], 888.0 [2], 2680.0 [3]
PanobinostatKi1.2 [1], 830.0 [2], 3200.0 [3]
Tubastatin AIC50621.0 [1], 4310.0 [2], 30000.0 [3]
RomidepsinIC5010000.0 [1], 50000.0 [2]
RomidepsinKi1100.0 [1]
TubacinIC504310.0 [1], 30000.0 [2]
TubacinKi509.3 [1], 6300.0 [2]
BelinostatKi24.0 [1], 250.0 [2]
DacinostatIC508.24 [1]
DacinostatKi9000.0 [1]
RicolinostatIC5010000.0 [1]
CID 53344908IC5019.4 [1], 20.0 [2], 23.24 [3]
ScriptaidIC50700.0 [1]
ScriptaidKi8000.0 [1]
LargazoleIC508330.0 [1], 10000.0 [2]
QuisinostatKi3.8 [1], 5.3 [2]
GivinostatKi390.0 [1]
(E)-N-Hydroxy-3-[2-(2-phenylethyl)-1-(2-pyrrolidin-1-ylethyl)benzimidazol-5-yl]prop-2-enamideKi19.0 [1], 19.2 [2]
(1r,2r,3r)-2-[4-(5-Fluoranylpyrimidin-2-Yl)phenyl]-N-Oxidanyl-3-Phenyl-Cyclopropane-1-CarboxamideIC50190.0 [1], 200.0 [2]
N-[[4-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]cyclohexyl]methyl]-4,4-dimethyl-2-oxo-1,3-dihydroquinoline-6-carboxamideIC505.2 [1], 91.0 [2]
N-[[4-[3-(Hydroxyamino)-3-oxopropyl]cyclohexyl]methyl]-4,4-dimethyl-2-oxo-1,3-dihydroquinoline-6-carboxamideIC5050.0 [1], 57.0 [2]
Valproic acidIC502000000.0 [1]
Butyric acidIC502000000.0 [1]
4-Phenylbutyric acidIC502000000.0 [1]
EntinostatIC50100000.0 [1]
N-HydroxybenzamideIC5033330.0 [1]
PracinostatKi24.0 [1]
Cudc-101IC5067.2 [1]
FimepinostatIC50554.0 [1]
1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-YL)thio]ethanoneIC50100000.0 [1]
Thailandepsin AIC5050000.0 [1]
Nexturastat AIC506720.0 [1]
Azumamide EIC5028000.0 [1]
N-Hydroxy-4-phenylbutanamideIC50430000.0 [1]
N-Hydroxy-2,2-diphenylacetamideIC50510.0 [1]
CID 11427204IC5082.0 [1]
2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamideIC50100000.0 [1]
2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanoneIC50100000.0 [1]
4-[2-[2-Hydroxyethyl(Phenyl)amino]-2-Oxidanylidene-Ethyl]-~{n}-Oxidanyl-BenzamideIC5010000.0 [1]
N-Hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamideIC5028.0 [1]
HDAC inhibitorIC502344.0 [1]
N-(4-{[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]acetyl}phenyl)acetamideIC5074100.0 [1]
(S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)carbamateIC501024.0 [1]
6-Methyl-2-{[2-oxo-2-(thiophen-2-yl)ethyl]sulfanyl}-3,4-dihydropyrimidin-4-oneIC50100000.0 [1]
N-Hydroxy-5-[[6-oxo-4-(4-phenylphenyl)-1H-pyrimidin-2-yl]sulfanyl]pentanamideIC5050000.0 [1]
(E)-N-Hydroxy-3-[4-(4-methoxyphenyl)phenyl]prop-2-enamideIC5039300.0 [1]
Pimelic Diphenylamide 106IC50100000.0 [1]
N-HydroxybutanamideIC502000000.0 [1]
N-[1-[[3-Azido-5-(azidomethyl)phenyl]methyl]pyrazol-4-yl]-N'-hydroxyoctanediamideIC50704.0 [1]
Thailandepsin BIC5050000.0 [1]
3-N-Hydroxy-1-N-(2-phenylethyl)benzene-1,3-dicarboxamideIC5033000.0 [1]
N-Hydroxy-2-propylpentanamideIC5091000.0 [1]
Benzamide, N-(((6-(hydroxyamino)-6-oxohexyl)amino)carbonyl)-Ki55.0 [1]
N-Hydroxy-4-[(quinolin-8-ylamino)methyl]benzamideIC501530.0 [1]
6-Methyl-2-phenacylsulfanyl-1H-pyrimidin-4-oneIC50100000.0 [1]
2-(4-Chlorophenacylthio)-4-hydroxy-6-methylpyrimidineIC50100000.0 [1]
PandacostatKi1400.0 [1]
5-[[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]methyl]-N-hydroxythiophene-2-carboxamideIC5010000.0 [1]
N-Hydroxy-7-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]octanamideIC508500.0 [1]
(E)-N-Hydroxy-3-[4-(4-hydroxyphenyl)phenyl]prop-2-enamideIC508920.0 [1]
2-(4-Methoxybenzyloxy)-N8-hydroxy-N1-phenyloctanediamideIC50247.0 [1]
(2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5-phenyl-2,4-pentadienamideIC504.2 [1]
(2E,4E)-N-Hydroxy-5-[4-(4-methoxyphenyl)phenyl]penta-2,4-dienamideIC50100000.0 [1]
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamideKi10000.0 [1]
1-[5-[3-[4-(1,3,4-Oxadiazole-2-yl)phenoxymethyl]-1,2,4-oxadiazole-5-yl]-2-thienyl]trifluoroethanoneIC5020.0 [1]
(E)-3-[1-[3-(Dimethylamino)-2,2-dimethylpropyl]-2-(2-phenylethyl)benzimidazol-5-yl]-N-hydroxyprop-2-enamideKi21.0 [1]
(3S,6S,9S,13S)-9-Methyl-13-(2-methylpropyl)-3-(naphthalen-1-ylmethyl)-6-(6-oxooctyl)-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetroneIC5010000.0 [1]
5-[4-[[3-Azido-5-(azidomethyl)benzoyl]amino]phenyl]-N-[7-(hydroxyamino)-7-oxoheptyl]-1,2-oxazole-3-carboxamideIC5037.8 [1]
(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]prop-2-enamideIC50100000.0 [1]
2-((3-Phenethoxyphenyl)Amino)BenzamideIC5030000.0 [1]
(1r,2r,3r)-2-[4-(1,3-Oxazol-5-Yl)phenyl]-N-Oxidanyl-3-Phenyl-Cyclopropane-1-CarboxamideIC5040.0 [1]
(E)-N-Hydroxy-3-[2-(2-phenylethyl)-1-(2-piperidin-1-ylethyl)benzimidazol-5-yl]prop-2-enamideKi24.0 [1]
(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]propanoic acidIC5058000.0 [1]
(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]-2-phenylacetic acidIC5034000.0 [1]
(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamideIC5035000.0 [1]
N-Hydroxy-2-[[5-(3-nitrophenyl)furan-2-yl]methyl]-3,4-dihydro-1H-isoquinoline-7-carboxamideIC5065800.0 [1]
N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamideIC50100000.0 [1]
2-(4-(4-(4-Fluorophenyl)-1-hydroxybut-3-en-2-yl)piperazin-1-yl)-N-hydroxypyrimidine-5-carboxamideIC5040.7 [1]
N-[7-(Hydroxyamino)-7-oxoheptyl]-2-methoxyquinoline-6-carboxamideIC5034.0 [1]
N-[7-(Hydroxyamino)-7-oxoheptyl]-2-oxo-1H-quinoline-6-carboxamideIC5046.0 [1]
N-[7-(Hydroxyamino)-7-oxoheptyl]-1,4,4-trimethyl-2-oxo-3H-quinoline-6-carboxamideIC50120.0 [1]
N-[7-(Hydroxyamino)-7-oxoheptyl]-1-methyl-2-oxoquinoline-6-carboxamideIC5041.0 [1]
N'-Hydroxy-N-(2-oxo-1H-quinolin-6-yl)octanediamideIC5058.0 [1]
4-[(1,1-Dioxo-2,3-dihydrothieno[3,2-b]indol-4-yl)methyl]-N-hydroxybenzamideIC50200.0 [1]
N-Hydroxy-5-(1-phenylpyrazol-3-yl)pentanamideIC5055800.0 [1]
5-[1-[(4-Anilinophenyl)methyl]pyrazol-3-yl]-N-hydroxypentanamideIC5018300.0 [1]
N-Hydroxy-5-[1-[(4-phenylphenyl)methyl]pyrazol-3-yl]pentanamideIC5047200.0 [1]
N-[6-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]pyridin-3-yl]-2,3-diphenylpropanamideIC5010600.0 [1]
3-(4-(Di(1H-indol-3-yl)methyl)phenyl)-N-hydroxyacrylamideIC503300.0 [1]
N-Hydroxy-7,7-bis(1H-indol-3-yl)heptanamideIC50640.0 [1]
N-Hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanamideIC50340.0 [1]
(1R,5S)-N-[2-Amino-5-(4-fluorophenyl)phenyl]-8-oxabicyclo[3.2.1]octane-3-carboxamideIC5033330.0 [1]
(3S,6Z,9R,12R,16S)-6-Ethylidene-3,12-di(propan-2-yl)-16-[(E)-4-sulfanylbut-1-enyl]-9-(sulfanylmethyl)-1-oxa-4,7,10,13-tetrazacyclohexadecane-2,5,8,11,14-pentoneIC5010000.0 [1]
(4Z,7S,10S,14R)-4-Ethylidene-7,14-di(propan-2-yl)-10-[(E)-4-sulfanylbut-1-enyl]-9-oxa-16-thia-3,6,13,18-tetrazabicyclo[13.2.1]octadeca-1(17),15(18)-diene-2,5,8,12-tetroneIC5010000.0 [1]
S-[(E)-4-[(4Z,7S,10S,14R)-4-Ethylidene-2,5,8,12-tetraoxo-7,14-di(propan-2-yl)-9-oxa-16-thia-3,6,13,18-tetrazabicyclo[13.2.1]octadeca-1(17),15(18)-dien-10-yl]but-3-enyl] octanethioateIC5010000.0 [1]
Hdac6-IN-1IC5010000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Histone deacetylase 9 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/histone-deacetylase-9-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Histone deacetylase 9 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/histone-deacetylase-9-inhibitors-ic50-ki.
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